Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Predicted Immune Epitope Results


The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


NeoepitopesYIFLGVAVV        Click here to BLAST against human proteome
CTL Epitope
(CTLPred)
Y
HLA I Alleles
(ProPred I)
HLA-A*0201, HLA-A*0205, HLA-A2, HLA-A2.1, HLA-B*51, HLA-B*5101, HLA-B*5102, HLA-B*5103, HLA-B*5201, HLA-B*5301, HLA-B*540111
HLA I Alleles
(nHLAPred)
HLA-B*5301, HLA-B*5401, HLA-B*51, HLA-Cw*0401, H2-Db, H2-Dd, H2-Kb, H2-Kd, H2-Ld, HLA-G, H-2Qa, Mamu-A*0112
HLA II Alleles
(PrePred)
DRB1_0101, DRB1_0102, DRB1_0305, DRB1_0309, DRB1_0401, DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0421, DRB1_0423, DRB1_0426, DRB1_0801, DRB1_0802, DRB1_0804, DRB1_0806, DRB1_0813, DRB1_0817, DRB1_1101, DRB1_1102, DRB1_1104, DRB1_1106, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1128, DRB1_1301, DRB1_1302, DRB1_1305, DRB1_1307, DRB1_1311, DRB1_1321, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_132835
B_Cell_Epitope
(ABCPred)
N

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package