Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
NR1H2CNKRSSDQPLARGE_INTESTINE238p.F243delc.726_728delCTTIn_Frame_Del40.11LOVON000Y
NR1H2KRSSDQPKVLARGE_INTESTINE240p.F243delc.726_728delCTTIn_Frame_Del30.11LOVON500N
NR1H2LQCNKRSSDLARGE_INTESTINE236p.F243delc.726_728delCTTIn_Frame_Del20.11LOVON000N
NR1H2NKRSSDQPKLARGE_INTESTINE239p.F243delc.726_728delCTTIn_Frame_Del40.11LOVON100Y
NR1H2QCNKRSSDQLARGE_INTESTINE237p.F243delc.726_728delCTTIn_Frame_Del30.11LOVON000N
NR1H2QLQCNKRSSLARGE_INTESTINE235p.F243delc.726_728delCTTIn_Frame_Del10.11LOVON000N
NR1H2RSSDQPKVTLARGE_INTESTINE241p.F243delc.726_728delCTTIn_Frame_Del20.11LOVON200N
NR1H2SSDQPKVTPLARGE_INTESTINE242p.F243delc.726_728delCTTIn_Frame_Del10.11LOVON000N