Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000224                                                              19     869
NP_852111                                                              19     869
NP_000136                                                              19     869
NP_000360                                                              19     869
XP_005268094                                                           19     869
XP_005264366                                                           19     869
XP_006712078                                                           19     869
NP_705618                                                              17    2528
NP_004289                                                              17    2528
NP_001265241                                                           17    2528
NP_001263629                                                           17    3301
NP_612202                                                              17    3301
NP_000907                                                              17    4312
NP_056161                                                              17    4312
XP_006720156                                                           17    4312
NP_001005213                                                           16    5631
NP_001013376                                                           16    5631
NP_001136245                                                           16    7355
NP_001136239                                                           16    7355
NP_065394                                                              16    7355
NP_001136236                                                           16    7355
NP_001136244                                                           16    7355
NP_001136238                                                           16    7355
NP_001136240                                                           16    7355
NP_001136243                                                           16    7355
NP_001136242                                                           16    7355
NP_001136235                                                           16    7355
NP_001136237                                                           16    7355
NP_001136241                                                           16    7355
NP_149045                                                              16    7355
NP_006085                                                              16    7355
NP_001157743                                                           16    7355
NP_872584                                                              16    7355
XP_006718013                                                           16    7355
XP_005273432                                                           16    7355
XP_005273431                                                           16    7355
NP_001004479                                                           16    7355
NP_002151                                                              15    9605
NP_005497                                                              15    9605
NP_001165402                                                           15    9605
NP_001165401                                                           15    9605
NP_071407                                                              15    9605
NP_001191184                                                           15    9605
XP_006718005                                                           15    9605
XP_006718004                                                           15    9605
XP_006718003                                                           15    9605
XP_005252032                                                           15    9605
XP_006717164                                                           15    9605
XP_005252031                                                           15    9605
XP_005252030                                                           15    9605
XP_006717163                                                           15    9605
XP_006717162                                                           15    9605
XP_006717161                                                           15    9605
XP_006717160                                                           15    9605
XP_005252029                                                           15    9605
XP_006717159                                                           15    9605
XP_005275746                                                           15    9605
XP_003403671                                                           15    9605
XP_006710003                                                           15    9605
NP_076411                                                              15    9605
>NP_000224
          Length = 699

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           YLLLI SVD
Sbjct: 411 YLLLIASVD 419
>NP_852111
          Length = 669

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           YLLLI SVD
Sbjct: 388 YLLLIASVD 396
>NP_000136
          Length = 695

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           YLLLI SVD
Sbjct: 414 YLLLIASVD 422
>NP_000360
          Length = 764

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           YLLLI SVD
Sbjct: 466 YLLLIASVD 474
>XP_005268094
          Length = 764

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           YLLLI SVD
Sbjct: 466 YLLLIASVD 474
>XP_005264366
          Length = 380

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           YLLLI SVD
Sbjct: 92  YLLLIASVD 100
>XP_006712078
          Length = 389

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           YLLLI SVD
Sbjct: 101 YLLLIASVD 109
>NP_705618
          Length = 1391

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YLLLITSVD 9
           YLL ITS D
Sbjct: 214 YLLTITSTD 222
>NP_004289
          Length = 1332

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YLLLITSVD 9
           YLL ITS D
Sbjct: 155 YLLTITSTD 163
>NP_001265241
          Length = 1327

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YLLLITSVD 9
           YLL ITS D
Sbjct: 214 YLLTITSTD 222
>NP_001263629
          Length = 891

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   YLLLITSV 8
           YLL ITSV
Sbjct: 419 YLLFITSV 426
>NP_612202
          Length = 892

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   YLLLITSV 8
           YLL ITSV
Sbjct: 419 YLLFITSV 426
>NP_000907
          Length = 389

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           YLLL+ S+D
Sbjct: 128 YLLLLMSLD 136
>NP_056161
          Length = 2539

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLLITSVD 9
           LLLITS D
Sbjct: 581 LLLITSAD 588
>XP_006720156
          Length = 2497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLLITSVD 9
           LLLITS D
Sbjct: 581 LLLITSAD 588
>NP_001005213
          Length = 305

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YLLLITSV 8
           YL +ITSV
Sbjct: 217 YLFIITSV 224
>NP_001013376
          Length = 305

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YLLLITSV 8
           YL +ITSV
Sbjct: 217 YLFIITSV 224
>NP_001136245
          Length = 1932

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 662 YILIITASD 670
>NP_001136239
          Length = 1915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 647 YILIITASD 655
>NP_065394
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   YLLLITS 7
           Y+LL+TS
Sbjct: 355 YILLVTS 361
>NP_001136236
          Length = 1957

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 684 YILIITASD 692
>NP_001136244
          Length = 1677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 684 YILIITASD 692
>NP_001136238
          Length = 1952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 684 YILIITASD 692
>NP_001136240
          Length = 1935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 662 YILIITASD 670
>NP_001136243
          Length = 1682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 689 YILIITASD 697
>NP_001136242
          Length = 1539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 684 YILIITASD 692
>NP_001136235
          Length = 1962

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 689 YILIITASD 697
>NP_001136237
          Length = 1886

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 613 YILIITASD 621
>NP_001136241
          Length = 1790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 696 YILIITASD 704
>NP_149045
          Length = 1955

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 684 YILIITASD 692
>NP_006085
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLITSVD 9
            LL+TSVD
Sbjct: 1007 LLLTSVD 1013
>NP_001157743
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLITSVD 9
           LL+TSVD
Sbjct: 933 LLLTSVD 939
>NP_872584
          Length = 1528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLITSVD 9
            LL+TSVD
Sbjct: 1444 LLLTSVD 1450
>XP_006718013
          Length = 1778

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L+IT+ D
Sbjct: 684 YILIITASD 692
>XP_005273432
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLITSVD 9
            LL+TSVD
Sbjct: 1041 LLLTSVD 1047
>XP_005273431
          Length = 1528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LLITSVD 9
            LL+TSVD
Sbjct: 1444 LLLTSVD 1450
>NP_001004479
          Length = 324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   YLLLITSV 8
           Y+LL+T+V
Sbjct: 228 YILLLTAV 235
>NP_002151
          Length = 2201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 1917 YLLVYESVD 1925
>NP_005497
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLLITSV 8
          LLL+TSV
Sbjct: 15 LLLVTSV 21
>NP_001165402
          Length = 1061

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L++ +VD
Sbjct: 742 YILIVRAVD 750
>NP_001165401
          Length = 1381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L++ +VD
Sbjct: 742 YILIVRAVD 750
>NP_071407
          Length = 3354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L++ +VD
Sbjct: 742 YILIVRAVD 750
>NP_001191184
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLLITSV 8
          LLL+TSV
Sbjct: 15 LLLVTSV 21
>XP_006718005
          Length = 3397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L++ +VD
Sbjct: 785 YILIVRAVD 793
>XP_006718004
          Length = 3399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L++ +VD
Sbjct: 787 YILIVRAVD 795
>XP_006718003
          Length = 3419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L++ +VD
Sbjct: 807 YILIVRAVD 815
>XP_005252032
          Length = 1564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 1280 YLLVYESVD 1288
>XP_006717164
          Length = 1655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 1371 YLLVYESVD 1379
>XP_005252031
          Length = 1655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 1371 YLLVYESVD 1379
>XP_005252030
          Length = 1837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 1553 YLLVYESVD 1561
>XP_006717163
          Length = 1928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 1644 YLLVYESVD 1652
>XP_006717162
          Length = 1928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 1644 YLLVYESVD 1652
>XP_006717161
          Length = 2019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 1735 YLLVYESVD 1743
>XP_006717160
          Length = 2110

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 1826 YLLVYESVD 1834
>XP_005252029
          Length = 2110

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 1826 YLLVYESVD 1834
>XP_006717159
          Length = 2293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLLLITSVD 9
            YLL+  SVD
Sbjct: 2009 YLLVYESVD 2017
>XP_005275746
          Length = 3352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L++ +VD
Sbjct: 740 YILIVRAVD 748
>XP_003403671
          Length = 3354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L++ +VD
Sbjct: 742 YILIVRAVD 750
>XP_006710003
          Length = 3374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YLLLITSVD 9
           Y+L++ +VD
Sbjct: 762 YILIVRAVD 770
>NP_076411
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLLITSV 8
           LLL+TSV
Sbjct: 133 LLLVTSV 139
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.150    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 355,204
Number of extensions: 577
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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