Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_065681                                                              20     299
NP_066124                                                              20     299
XP_006717999                                                           20     299
NP_115575                                                              16    5631
NP_001231567                                                           16    5631
NP_057494                                                              16    7355
NP_001161846                                                           16    7355
NP_001161849                                                           16    7355
NP_036542                                                              16    7355
NP_001161848                                                           16    7355
NP_055624                                                              16    7355
NP_001107572                                                           16    7355
NP_001107571                                                           16    7355
NP_001004326                                                           16    7355
NP_963869                                                              16    7355
NP_001230262                                                           16    7355
NP_001230261                                                           16    7355
NP_001161847                                                           16    7355
XP_005255309                                                           16    7355
XP_005274066                                                           16    7355
XP_006715351                                                           16    7355
XP_006715350                                                           16    7355
XP_006715349                                                           16    7355
XP_005249561                                                           16    7355
NP_060954                                                              16    7355
NP_001191088                                                           15    9605
NP_005793                                                              15    9605
NP_001191089                                                           15    9605
NP_064511                                                              15    9605
NP_001007535                                                           15    9605
NP_001034678                                                           15    9605
NP_006390                                                              15    9605
NP_001375                                                              15    9605
NP_001275882                                                           15    9605
NP_065191                                                              15    9605
NP_001275884                                                           15    9605
NP_001275880                                                           15    9605
NP_066923                                                              15    9605
NP_001185918                                                           15    9605
NP_001185731                                                           15    9605
NP_001185730                                                           15    9605
NP_001010854                                                           15    9605
NP_003751                                                              15    9605
NP_001161707                                                           15    9605
NP_036237                                                              15    9605
NP_620477                                                              15    9605
NP_620476                                                              15    9605
NP_001185732                                                           15    9605
XP_006723355                                                           15    9605
XP_006723354                                                           15    9605
XP_006723353                                                           15    9605
XP_005267424                                                           15    9605
XP_006720122                                                           15    9605
XP_006720121                                                           15    9605
XP_006715967                                                           15    9605
XP_006715966                                                           15    9605
XP_006715965                                                           15    9605
XP_006715964                                                           15    9605
XP_006715963                                                           15    9605
XP_005262923                                                           15    9605
XP_005262922                                                           15    9605
XP_005262921                                                           15    9605
XP_005262920                                                           15    9605
XP_005262919                                                           15    9605
XP_005262918                                                           15    9605
XP_005264496                                                           15    9605
XP_005270616                                                           15    9605
>NP_065681
          Length = 1072

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLELAASTP 9
            YL+LAASTP
Sbjct: 1015 YLDLAASTP 1023
>NP_066124
          Length = 1114

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLELAASTP 9
            YL+LAASTP
Sbjct: 1015 YLDLAASTP 1023
>XP_006717999
          Length = 1207

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLELAASTP 9
            YL+LAASTP
Sbjct: 1108 YLDLAASTP 1116
>NP_115575
          Length = 1188

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YLELAASTP 9
            Y  LAA+TP
Sbjct: 1141 YRHLAAATP 1149
>NP_001231567
          Length = 945

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           Y  LAA+TP
Sbjct: 898 YRHLAAATP 906
>NP_057494
          Length = 219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL+ AAS P
Sbjct: 182 YLDEAASAP 190
>NP_001161846
          Length = 1063

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL  +ASTP
Sbjct: 208 YLNESASTP 216
>NP_001161849
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL  +ASTP
Sbjct: 217 YLNESASTP 225
>NP_036542
          Length = 853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           Y+EL + TP
Sbjct: 368 YVELLSETP 376
>NP_001161848
          Length = 1027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL  +ASTP
Sbjct: 172 YLNESASTP 180
>NP_055624
          Length = 1072

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL  +ASTP
Sbjct: 217 YLNESASTP 225
>NP_001107572
          Length = 809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           Y+EL + TP
Sbjct: 324 YVELLSETP 332
>NP_001107571
          Length = 840

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           Y+EL + TP
Sbjct: 368 YVELLSETP 376
>NP_001004326
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   YLELAAS 7
           YL+LAAS
Sbjct: 173 YLQLAAS 179
>NP_963869
          Length = 910

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           Y+EL + TP
Sbjct: 438 YVELLSETP 446
>NP_001230262
          Length = 879

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           Y+EL + TP
Sbjct: 394 YVELLSETP 402
>NP_001230261
          Length = 923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           Y+EL + TP
Sbjct: 438 YVELLSETP 446
>NP_001161847
          Length = 1072

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL  +ASTP
Sbjct: 217 YLNESASTP 225
>XP_005255309
          Length = 859

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           Y+EL + TP
Sbjct: 438 YVELLSETP 446
>XP_005274066
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   YLELAAS 7
           YL+LAAS
Sbjct: 173 YLQLAAS 179
>XP_006715351
          Length = 920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  YLELAASTP 9
          YL  +ASTP
Sbjct: 65 YLNESASTP 73
>XP_006715350
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL  +ASTP
Sbjct: 279 YLNESASTP 287
>XP_006715349
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL  +ASTP
Sbjct: 279 YLNESASTP 287
>XP_005249561
          Length = 1134

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL  +ASTP
Sbjct: 279 YLNESASTP 287
>NP_060954
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           L+LAAS P
Sbjct: 258 LQLAASVP 265
>NP_001191088
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LAASTP 9
          LAASTP
Sbjct: 44 LAASTP 49
>NP_005793
          Length = 1045

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  ELAASTP 9
          ELAAS P
Sbjct: 51 ELAASAP 57
>NP_001191089
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LAASTP 9
          LAASTP
Sbjct: 8  LAASTP 13
>NP_064511
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LAASTP 9
          LAASTP
Sbjct: 44 LAASTP 49
>NP_001007535
          Length = 242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LAASTP 9
          LAASTP
Sbjct: 28 LAASTP 33
>NP_001034678
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LELA S+P
Sbjct: 212 LELAESSP 219
>NP_006390
          Length = 125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LAASTP 9
           LAASTP
Sbjct: 96  LAASTP 101
>NP_001375
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL+L  S+P
Sbjct: 172 YLDLLVSSP 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LELA S+P
Sbjct: 440 LELAESSP 447
>NP_001275882
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LEL AS+P
Sbjct: 806 LELEASSP 813
>NP_065191
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LEL AS+P
Sbjct: 840 LELEASSP 847
>NP_001275884
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LEL AS+P
Sbjct: 486 LELEASSP 493
>NP_001275880
          Length = 882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LEL AS+P
Sbjct: 864 LELEASSP 871
>NP_066923
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  YLELAASTP 9
          Y+++ A+TP
Sbjct: 60 YMDVQATTP 68
>NP_001185918
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  YLELAASTP 9
          Y+++ A+TP
Sbjct: 60 YMDVQATTP 68
>NP_001185731
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LAASTP 9
           LAASTP
Sbjct: 210 LAASTP 215
>NP_001185730
          Length = 1621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LAASTP 9
           LAASTP
Sbjct: 203 LAASTP 208
>NP_001010854
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LEL AS+P
Sbjct: 825 LELEASSP 832
>NP_003751
          Length = 1585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LAASTP 9
           LAASTP
Sbjct: 204 LAASTP 209
>NP_001161707
          Length = 2139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    YLELAASTP 9
            YLE  AS P
Sbjct: 1117 YLEKIASAP 1125
>NP_036237
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   YLELAASTP 9
           YLE+   TP
Sbjct: 93  YLEMLIGTP 101
>NP_620477
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   YLELAASTP 9
           YLE+   TP
Sbjct: 93  YLEMLIGTP 101
>NP_620476
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   YLELAASTP 9
           YLE+   TP
Sbjct: 93  YLEMLIGTP 101
>NP_001185732
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LAASTP 9
           LAASTP
Sbjct: 215 LAASTP 220
>XP_006723355
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LAASTP 9
          LAASTP
Sbjct: 8  LAASTP 13
>XP_006723354
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LAASTP 9
          LAASTP
Sbjct: 44 LAASTP 49
>XP_006723353
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LAASTP 9
           LAASTP
Sbjct: 106 LAASTP 111
>XP_005267424
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LEL AS+P
Sbjct: 638 LELEASSP 645
>XP_006720122
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LEL AS+P
Sbjct: 802 LELEASSP 809
>XP_006720121
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LEL AS+P
Sbjct: 833 LELEASSP 840
>XP_006715967
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LELAASTP 9
           L LAA TP
Sbjct: 250 LNLAAQTP 257
>XP_006715966
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LELAASTP 9
           L LAA TP
Sbjct: 551 LNLAAQTP 558
>XP_006715965
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LELAASTP 9
           L LAA TP
Sbjct: 551 LNLAAQTP 558
>XP_006715964
          Length = 964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LELAASTP 9
           L LAA TP
Sbjct: 551 LNLAAQTP 558
>XP_006715963
          Length = 975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LELAASTP 9
           L LAA TP
Sbjct: 551 LNLAAQTP 558
>XP_005262923
          Length = 1018

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELAASTP 9
           ELAA TP
Sbjct: 317 ELAACTP 323
>XP_005262922
          Length = 1276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELAASTP 9
           ELAA TP
Sbjct: 699 ELAACTP 705
>XP_005262921
          Length = 1309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELAASTP 9
           ELAA TP
Sbjct: 699 ELAACTP 705
>XP_005262920
          Length = 1347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELAASTP 9
           ELAA TP
Sbjct: 699 ELAACTP 705
>XP_005262919
          Length = 1383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELAASTP 9
           ELAA TP
Sbjct: 699 ELAACTP 705
>XP_005262918
          Length = 1400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ELAASTP 9
           ELAA TP
Sbjct: 699 ELAACTP 705
>XP_005264496
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LEL AS+P
Sbjct: 721 LELEASSP 728
>XP_005270616
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YLELAASTP 9
           YL+L  S+P
Sbjct: 96  YLDLLVSSP 104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LELAASTP 9
           LELA S+P
Sbjct: 364 LELAESSP 371
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.122    0.328 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 491,589
Number of extensions: 1075
Number of successful extensions: 69
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package