Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003473                                                              20     390
NP_733751                                                              20     390
XP_006719679                                                           20     390
XP_005269219                                                           20     390
XP_006719678                                                           20     390
XP_006719677                                                           20     390
XP_006716142                                                           20     390
XP_005250088                                                           20     390
XP_006716141                                                           20     390
XP_005250085                                                           20     390
XP_006716140                                                           20     390
XP_005250084                                                           20     390
XP_005250083                                                           20     390
XP_005250082                                                           20     390
XP_005248127                                                           17    2528
XP_005248124                                                           17    2528
XP_005248123                                                           17    2528
XP_005248122                                                           17    2528
XP_005248121                                                           17    2528
XP_006714059                                                           17    2528
XP_005248119                                                           17    2528
XP_005248118                                                           17    2528
XP_005248117                                                           17    2528
XP_005248116                                                           17    2528
XP_005248115                                                           17    2528
XP_005248114                                                           17    2528
NP_839943                                                              17    3301
NP_109587                                                              16    5631
NP_997191                                                              16    7355
NP_001152956                                                           16    7355
XP_006711682                                                           16    7355
NP_005198                                                              15    9605
NP_009123                                                              15    9605
>NP_003473
          Length = 5537

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 5400 YLARSRIQG 5408
>NP_733751
          Length = 4911

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 4774 YLARSRIQG 4782
>XP_006719679
          Length = 5536

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 5399 YLARSRIQG 5407
>XP_005269219
          Length = 5537

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 5400 YLARSRIQG 5408
>XP_006719678
          Length = 5539

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 5402 YLARSRIQG 5410
>XP_006719677
          Length = 5540

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 5403 YLARSRIQG 5411
>XP_006716142
          Length = 4927

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 4790 YLARSRIQG 4798
>XP_005250088
          Length = 4928

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 4791 YLARSRIQG 4799
>XP_006716141
          Length = 4959

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 4822 YLARSRIQG 4830
>XP_005250085
          Length = 4979

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 4842 YLARSRIQG 4850
>XP_006716140
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 4845 YLARSRIQG 4853
>XP_005250084
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 4845 YLARSRIQG 4853
>XP_005250083
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 4845 YLARSRIQG 4853
>XP_005250082
          Length = 4983

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    YLAQSRIQG 9
            YLA+SRIQG
Sbjct: 4846 YLARSRIQG 4854
>XP_005248127
          Length = 1322

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 541 LAQQRIQG 548
>XP_005248124
          Length = 1467

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 382 LAQQRIQG 389
>XP_005248123
          Length = 1471

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 382 LAQQRIQG 389
>XP_005248122
          Length = 1471

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 382 LAQQRIQG 389
>XP_005248121
          Length = 1543

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 454 LAQQRIQG 461
>XP_006714059
          Length = 1600

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 541 LAQQRIQG 548
>XP_005248119
          Length = 1601

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 541 LAQQRIQG 548
>XP_005248118
          Length = 1602

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 541 LAQQRIQG 548
>XP_005248117
          Length = 1626

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 541 LAQQRIQG 548
>XP_005248116
          Length = 1627

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 541 LAQQRIQG 548
>XP_005248115
          Length = 1629

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 541 LAQQRIQG 548
>XP_005248114
          Length = 1630

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           LAQ RIQG
Sbjct: 541 LAQQRIQG 548
>NP_839943
          Length = 1631

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YLAQSRIQG 9
           YL Q+ IQG
Sbjct: 278 YLTQAEIQG 286
>NP_109587
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YLAQSRIQG 9
           Y+A  R+QG
Sbjct: 233 YMAPERLQG 241
>NP_997191
          Length = 1888

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LAQSRIQ 8
            LAQSR+Q
Sbjct: 1874 LAQSRLQ 1880
>NP_001152956
          Length = 1736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LAQSRIQ 8
            LAQSR+Q
Sbjct: 1722 LAQSRLQ 1728
>XP_006711682
          Length = 1739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LAQSRIQ 8
            LAQSR+Q
Sbjct: 1725 LAQSRLQ 1731
>NP_005198
          Length = 303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AQSRIQG 9
          AQ+R+QG
Sbjct: 24 AQTRLQG 30
>NP_009123
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LAQSRIQG 9
           +AQ R+QG
Sbjct: 671 IAQKRMQG 678
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.134    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 296,997
Number of extensions: 334
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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