Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001124335                                                           18    1935
NP_006200                                                              18    1935
NP_001035181                                                           18    1935
XP_006716650                                                           18    1935
XP_006716649                                                           18    1935
XP_006716648                                                           18    1935
XP_006716647                                                           18    1935
XP_005249810                                                           17    2528
NP_001274278                                                           17    3301
NP_001265593                                                           17    3301
NP_975011                                                              17    3301
NP_001265606                                                           17    3301
NP_001265592                                                           17    3301
NP_001265607                                                           17    3301
NP_001265590                                                           17    3301
NP_001265591                                                           17    3301
XP_005260237                                                           17    3301
XP_005260226                                                           17    3301
XP_006723012                                                           17    3301
XP_006723011                                                           17    3301
XP_005260225                                                           17    3301
XP_005260224                                                           17    3301
XP_005260223                                                           17    3301
NP_110439                                                              17    4312
NP_001277137                                                           17    4312
NP_001277138                                                           17    4312
NP_001121695                                                           17    4312
XP_006712976                                                           17    4312
XP_006712975                                                           17    4312
XP_006712974                                                           17    4312
XP_005264770                                                           17    4312
XP_005264768                                                           17    4312
XP_005264767                                                           17    4312
XP_006712973                                                           17    4312
NP_000382                                                              16    7355
NP_055978                                                              16    7355
NP_001007467                                                           16    7355
NP_064630                                                              16    7355
NP_056144                                                              16    7355
NP_003421                                                              16    7355
NP_001004342                                                           16    7355
NP_001230967                                                           16    7355
XP_006722944                                                           16    7355
XP_006722943                                                           16    7355
XP_006722942                                                           16    7355
XP_006722941                                                           16    7355
XP_006722774                                                           16    7355
XP_005259895                                                           16    7355
XP_005259894                                                           16    7355
XP_006720081                                                           16    7355
XP_006720080                                                           16    7355
XP_005267114                                                           16    7355
XP_005273195                                                           16    7355
XP_005273194                                                           16    7355
NP_000668                                                              15    9605
NP_073739                                                              15    9605
NP_055247                                                              15    9605
NP_001265651                                                           15    9605
NP_001265653                                                           15    9605
NP_001265652                                                           15    9605
NP_031377                                                              15    9605
NP_955452                                                              15    9605
NP_714544                                                              15    9605
NP_065102                                                              15    9605
XP_006720470                                                           15    9605
XP_006715569                                                           15    9605
XP_006715568                                                           15    9605
XP_005262913                                                           15    9605
XP_006713543                                                           15    9605
XP_006710049                                                           15    9605
>NP_001124335
          Length = 888

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WSMVITNER 9
           WS+VI +ER
Sbjct: 276 WSVVIPHER 284
>NP_006200
          Length = 915

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WSMVITNER 9
           WS+VI +ER
Sbjct: 276 WSVVIPHER 284
>NP_001035181
          Length = 863

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WSMVITNER 9
           WS+VI +ER
Sbjct: 276 WSVVIPHER 284
>XP_006716650
          Length = 911

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WSMVITNER 9
           WS+VI +ER
Sbjct: 276 WSVVIPHER 284
>XP_006716649
          Length = 936

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WSMVITNER 9
           WS+VI +ER
Sbjct: 272 WSVVIPHER 280
>XP_006716648
          Length = 936

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WSMVITNER 9
           WS+VI +ER
Sbjct: 276 WSVVIPHER 284
>XP_006716647
          Length = 940

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WSMVITNER 9
           WS+VI +ER
Sbjct: 276 WSVVIPHER 284
>XP_005249810
          Length = 390

 Score = 17.3 bits (33), Expect =  2528
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   WSMVITNER 9
           W++V+T+E+
Sbjct: 358 WALVLTSEK 366
>NP_001274278
          Length = 530

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  WSMVITNER 9
          W+M++ N+R
Sbjct: 34 WNMMLENDR 42
>NP_001265593
          Length = 586

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 148 WSSTLTNHR 156
>NP_975011
          Length = 659

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 221 WSSTLTNHR 229
>NP_001265606
          Length = 618

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 180 WSSTLTNHR 188
>NP_001265592
          Length = 574

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 136 WSSTLTNHR 144
>NP_001265607
          Length = 574

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 136 WSSTLTNHR 144
>NP_001265590
          Length = 618

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 180 WSSTLTNHR 188
>NP_001265591
          Length = 618

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 180 WSSTLTNHR 188
>XP_005260237
          Length = 356

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WSMVITNER 9
          WS ++TN +
Sbjct: 29 WSSILTNNK 37
>XP_005260226
          Length = 491

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 221 WSSTLTNHR 229
>XP_006723012
          Length = 574

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 136 WSSTLTNHR 144
>XP_006723011
          Length = 574

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 136 WSSTLTNHR 144
>XP_005260225
          Length = 574

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 136 WSSTLTNHR 144
>XP_005260224
          Length = 574

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 136 WSSTLTNHR 144
>XP_005260223
          Length = 631

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN R
Sbjct: 221 WSSTLTNHR 229
>NP_110439
          Length = 366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WSMVITNER 9
          WS V+ N R
Sbjct: 82 WSFVLENHR 90
>NP_001277137
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W +VITN
Sbjct: 113 WQIVITN 119
>NP_001277138
          Length = 864

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  WSMVITN 7
          W +VITN
Sbjct: 63 WQIVITN 69
>NP_001121695
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_006712976
          Length = 635

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_006712975
          Length = 907

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W +VITN
Sbjct: 106 WQIVITN 112
>XP_006712974
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_005264770
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_005264768
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_005264767
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W +VITN
Sbjct: 113 WQIVITN 119
>XP_006712973
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W +VITN
Sbjct: 113 WQIVITN 119
>NP_000382
          Length = 563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   WSMVITNE 8
           W M+++NE
Sbjct: 307 WLMLLSNE 314
>NP_055978
          Length = 710

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           W+M + N R
Sbjct: 616 WAMYVDNNR 624
>NP_001007467
          Length = 678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WSMVITNER 9
           WS+ + N+R
Sbjct: 116 WSVELVNDR 124
>NP_064630
          Length = 1543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WSMVITNER 9
           WS+ + N+R
Sbjct: 116 WSVELVNDR 124
>NP_056144
          Length = 613

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W+ ++TN
Sbjct: 415 WAFIVTN 421
>NP_003421
          Length = 1191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN +
Sbjct: 221 WSSTLTNHK 229
>NP_001004342
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           W+M + N R
Sbjct: 688 WAMYVDNNR 696
>NP_001230967
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN +
Sbjct: 212 WSSTLTNHK 220
>XP_006722944
          Length = 883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN +
Sbjct: 221 WSSTLTNHK 229
>XP_006722943
          Length = 1092

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN +
Sbjct: 122 WSSTLTNHK 130
>XP_006722942
          Length = 1159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN +
Sbjct: 189 WSSTLTNHK 197
>XP_006722941
          Length = 1163

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           WS  +TN +
Sbjct: 221 WSSTLTNHK 229
>XP_006722774
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W+ ++TN
Sbjct: 454 WAFIVTN 460
>XP_005259895
          Length = 624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W+ ++TN
Sbjct: 426 WAFIVTN 432
>XP_005259894
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 1   WSMVITN 7
           W+ ++TN
Sbjct: 454 WAFIVTN 460
>XP_006720081
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           W+M + N R
Sbjct: 701 WAMYVDNNR 709
>XP_006720080
          Length = 806

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           W+M + N R
Sbjct: 701 WAMYVDNNR 709
>XP_005267114
          Length = 1543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WSMVITNER 9
           WS+ + N+R
Sbjct: 116 WSVELVNDR 124
>XP_005273195
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           W+M + N R
Sbjct: 626 WAMYVDNNR 634
>XP_005273194
          Length = 756

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WSMVITNER 9
           W+M + N R
Sbjct: 688 WAMYVDNNR 696
>NP_000668
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   WSMVITNE 8
           W+M +T+E
Sbjct: 149 WNMKLTSE 156
>NP_073739
          Length = 1430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    WSMVITNER 9
            WS   +NER
Sbjct: 1310 WSTTPSNER 1318
>NP_055247
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1   WSMVITN 7
           WS  +TN
Sbjct: 194 WSQCVTN 200
>NP_001265651
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1   WSMVITN 7
           WS  +TN
Sbjct: 145 WSQCVTN 151
>NP_001265653
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1  WSMVITN 7
          WS  +TN
Sbjct: 61 WSQCVTN 67
>NP_001265652
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1  WSMVITN 7
          WS  +TN
Sbjct: 83 WSQCVTN 89
>NP_031377
          Length = 1228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VITNER 9
           V+TNER
Sbjct: 885 VVTNER 890
>NP_955452
          Length = 2590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 7/8 (87%)

Query: 1    WSMVITNE 8
            W++ +TN+
Sbjct: 1124 WNITLTND 1131
>NP_714544
          Length = 1775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    WSMVIT 6
            WS+V+T
Sbjct: 1762 WSLVLT 1767
>NP_065102
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 7/8 (87%)

Query: 1  WSMVITNE 8
          W ++++NE
Sbjct: 50 WEILVSNE 57
>XP_006720470
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    WSMVIT 6
            WS+V+T
Sbjct: 1004 WSLVLT 1009
>XP_006715569
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1  WSMVITN 7
          WS  +TN
Sbjct: 61 WSQCVTN 67
>XP_006715568
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1   WSMVITN 7
           WS  +TN
Sbjct: 172 WSQCVTN 178
>XP_005262913
          Length = 1193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VITNER 9
           V+TNER
Sbjct: 850 VVTNER 855
>XP_006713543
          Length = 2591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 7/8 (87%)

Query: 1    WSMVITNE 8
            W++ +TN+
Sbjct: 1125 WNITLTND 1132
>XP_006710049
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   WSMVIT 6
           WS+V+T
Sbjct: 280 WSLVLT 285
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.123    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 448,610
Number of extensions: 937
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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