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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_065681                                                              18    1935
NP_066124                                                              18    1935
NP_872344                                                              18    1935
XP_006717999                                                           18    1935
XP_006716128                                                           17    2528
NP_001171486                                                           17    4312
NP_001245330                                                           17    4312
NP_001035049                                                           17    4312
NP_001171487                                                           17    4312
XP_005246752                                                           17    4312
XP_005246751                                                           17    4312
XP_006712706                                                           17    4312
XP_006712705                                                           17    4312
XP_006712704                                                           17    4312
XP_005246750                                                           17    4312
NP_071341                                                              17    4312
NP_612191                                                              16    5631
NP_612190                                                              16    5631
NP_066984                                                              16    5631
NP_001012301                                                           16    7355
XP_005246905                                                           16    7355
NP_077269                                                              16    7355
NP_000192                                                              15    9605
NP_001036054                                                           15    9605
NP_005595                                                              15    9605
NP_001036055                                                           15    9605
NP_071765                                                              15    9605
NP_056210                                                              15    9605
XP_006726566                                                           15    9605
XP_006717411                                                           15    9605
XP_006716846                                                           15    9605
XP_006716844                                                           15    9605
XP_005251541                                                           15    9605
XP_006716843                                                           15    9605
XP_005251540                                                           15    9605
XP_005250310                                                           15    9605
XP_006710279                                                           15    9605

>NP_065681
          Length = 1072

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RTVIAAAV 9
           RTVIAAAV
Sbjct: 635 RTVIAAAV 642



>NP_066124
          Length = 1114

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RTVIAAAV 9
           RTVIAAAV
Sbjct: 635 RTVIAAAV 642



>NP_872344
          Length = 512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  WRTVIAAAV 9
          WR  +AAAV
Sbjct: 42 WRAYVAAAV 50



>XP_006717999
          Length = 1207

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RTVIAAAV 9
           RTVIAAAV
Sbjct: 728 RTVIAAAV 735



>XP_006716128
          Length = 370

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   WRTVIAAA 8
           WR V+AAA
Sbjct: 336 WRWVVAAA 343



>NP_001171486
          Length = 1118

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 811 WWTVIAAII 819



>NP_001245330
          Length = 1040

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 727 WWTVIAAII 735



>NP_001035049
          Length = 1093

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 780 WWTVIAAII 788



>NP_001171487
          Length = 1099

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 792 WWTVIAAII 800



>XP_005246752
          Length = 1117

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 792 WWTVIAAII 800



>XP_005246751
          Length = 1147

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 822 WWTVIAAII 830



>XP_006712706
          Length = 1148

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 823 WWTVIAAII 831



>XP_006712705
          Length = 1174

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 849 WWTVIAAII 857



>XP_006712704
          Length = 1204

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 879 WWTVIAAII 887



>XP_005246750
          Length = 1205

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 880 WWTVIAAII 888



>NP_071341
          Length = 1088

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           W TVIAA +
Sbjct: 781 WWTVIAAII 789



>NP_612191
          Length = 543

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  WRTVIAAAV 9
          W+TV+A  V
Sbjct: 74 WKTVVAIFV 82



>NP_612190
          Length = 543

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  WRTVIAAAV 9
          W+TV+A  V
Sbjct: 74 WKTVVAIFV 82



>NP_066984
          Length = 538

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  WRTVIAAAV 9
          W+TV+A  V
Sbjct: 69 WKTVVAIFV 77



>NP_001012301
          Length = 569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WRTVIAAAV 9
           W T + AA+
Sbjct: 411 WNTAVQAAI 419



>XP_005246905
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WRTVIAAA 8
          W  V+AAA
Sbjct: 63 WEAVLAAA 70



>NP_077269
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WRTVIAAA 8
          W  V+AAA
Sbjct: 63 WEAVLAAA 70



>NP_000192
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVIAAAV 9
           TV+AAAV
Sbjct: 485 TVVAAAV 491



>NP_001036054
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WRTVIAAA 8
           W TVIA A
Sbjct: 307 WVTVIAMA 314



>NP_005595
          Length = 443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   WRTVIAAA 8
           WR+  AAA
Sbjct: 168 WRSAAAAA 175



>NP_001036055
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WRTVIAAA 8
           W TVIA A
Sbjct: 307 WVTVIAMA 314



>NP_071765
          Length = 1386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   WRTVIAAA 8
           +RT++AAA
Sbjct: 841 YRTLVAAA 848



>NP_056210
          Length = 1165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   WRTVIAA 7
           W+ +IAA
Sbjct: 372 WKAIIAA 378



>XP_006726566
          Length = 963

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           WR V+A ++
Sbjct: 747 WRKVVAVSM 755



>XP_006717411
          Length = 963

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           WR V+A ++
Sbjct: 747 WRKVVAVSM 755



>XP_006716846
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WRTVIAAA 8
           W TVIA A
Sbjct: 307 WVTVIAMA 314



>XP_006716844
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WRTVIAAA 8
           W TVIA A
Sbjct: 474 WVTVIAMA 481



>XP_005251541
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WRTVIAAA 8
           W TVIA A
Sbjct: 759 WVTVIAMA 766



>XP_006716843
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WRTVIAAA 8
           W TVIA A
Sbjct: 759 WVTVIAMA 766



>XP_005251540
          Length = 934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WRTVIAAA 8
           W TVIA A
Sbjct: 759 WVTVIAMA 766



>XP_005250310
          Length = 1165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   WRTVIAA 7
           W+ +IAA
Sbjct: 372 WKAIIAA 378



>XP_006710279
          Length = 963

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WRTVIAAAV 9
           WR V+A ++
Sbjct: 747 WRKVVAVSM 755



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.124    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 370,379
Number of extensions: 401
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)