Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001193762                                                           17    2528
NP_874369                                                              17    2528
NP_006379                                                              17    2528
NP_874368                                                              17    2528
XP_006718484                                                           17    2528
NP_001001894                                                           17    3301
NP_003307                                                              17    3301
XP_005261115                                                           17    3301
XP_005261111                                                           17    3301
XP_005261109                                                           17    3301
XP_005261110                                                           17    3301
XP_005261108                                                           17    3301
XP_005261106                                                           17    3301
XP_005261107                                                           17    3301
XP_005261105                                                           17    3301
XP_005261104                                                           17    3301
XP_005261103                                                           17    3301
XP_005261102                                                           17    3301
NP_001073911                                                           16    5631
NP_001243690                                                           16    5631
NP_001243689                                                           16    5631
NP_000859                                                              16    5631
NP_001229416                                                           16    5631
NP_001229417                                                           16    5631
NP_055852                                                              16    5631
XP_006726695                                                           16    5631
XP_006721198                                                           16    5631
XP_005269712                                                           16    5631
XP_006717788                                                           16    5631
XP_005269710                                                           16    5631
XP_005269709                                                           16    5631
XP_005269708                                                           16    5631
XP_005269706                                                           16    5631
XP_005269705                                                           16    5631
NP_005017                                                              16    7355
NP_001273063                                                           16    7355
NP_068751                                                              16    7355
NP_073563                                                              16    7355
NP_775809                                                              16    7355
NP_001258629                                                           16    7355
NP_060549                                                              16    7355
NP_919278                                                              16    7355
XP_006721217                                                           16    7355
XP_005255871                                                           16    7355
XP_006718333                                                           16    7355
XP_005253109                                                           16    7355
XP_006716575                                                           16    7355
XP_006712459                                                           16    7355
XP_005264455                                                           16    7355
XP_006710753                                                           16    7355
XP_005263530                                                           16    7355
XP_006710752                                                           16    7355
XP_006710751                                                           16    7355
XP_006710750                                                           16    7355
XP_006710749                                                           16    7355
NP_631913                                                              16    7355
NP_001138872                                                           16    7355
NP_000042                                                              15    9605
NP_003030                                                              15    9605
NP_055178                                                              15    9605
NP_001264984                                                           15    9605
NP_000253                                                              15    9605
NP_997303                                                              15    9605
XP_005261674                                                           15    9605
XP_005261673                                                           15    9605
XP_005261672                                                           15    9605
XP_005266395                                                           15    9605
XP_005271621                                                           15    9605
XP_006718907                                                           15    9605
XP_006718906                                                           15    9605
XP_005271619                                                           15    9605
XP_005271618                                                           15    9605
XP_006710899                                                           15    9605
XP_005263548                                                           15    9605
>NP_001193762
          Length = 494

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  WPLLSILS 8
          WPL  ILS
Sbjct: 59 WPLAEILS 66
>NP_874369
          Length = 546

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  WPLLSILS 8
          WPL  ILS
Sbjct: 59 WPLAEILS 66
>NP_006379
          Length = 513

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  WPLLSILS 8
          WPL  ILS
Sbjct: 26 WPLAEILS 33
>NP_874368
          Length = 461

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  WPLLSILS 8
          WPL  ILS
Sbjct: 26 WPLAEILS 33
>XP_006718484
          Length = 522

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  WPLLSILS 8
          WPL  ILS
Sbjct: 26 WPLAEILS 33
>NP_001001894
          Length = 2025

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 191 WPMLSI 196
>NP_003307
          Length = 2025

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 191 WPMLSI 196
>XP_005261115
          Length = 1077

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 229 WPMLSI 234
>XP_005261111
          Length = 2043

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 191 WPMLSI 196
>XP_005261109
          Length = 2043

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 191 WPMLSI 196
>XP_005261110
          Length = 2043

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 191 WPMLSI 196
>XP_005261108
          Length = 2047

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 213 WPMLSI 218
>XP_005261106
          Length = 2059

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 207 WPMLSI 212
>XP_005261107
          Length = 2059

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 207 WPMLSI 212
>XP_005261105
          Length = 2059

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 207 WPMLSI 212
>XP_005261104
          Length = 2063

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 229 WPMLSI 234
>XP_005261103
          Length = 2065

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 213 WPMLSI 218
>XP_005261102
          Length = 2081

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WPLLSI 6
           WP+LSI
Sbjct: 229 WPMLSI 234
>NP_001073911
          Length = 435

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WPLLSILS 8
           W L+S+LS
Sbjct: 250 WALVSVLS 257
>NP_001243690
          Length = 248

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  WPLLSIL 7
          WP LSI+
Sbjct: 55 WPALSIV 61
>NP_001243689
          Length = 458

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  WPLLSIL 7
          WP LSI+
Sbjct: 55 WPALSIV 61
>NP_000859
          Length = 458

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  WPLLSIL 7
          WP LSI+
Sbjct: 55 WPALSIV 61
>NP_001229416
          Length = 1837

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W LLSI+ E
Sbjct: 348 WNLLSIVRE 356
>NP_001229417
          Length = 1892

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W LLSI+ E
Sbjct: 348 WNLLSIVRE 356
>NP_055852
          Length = 1842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W LLSI+ E
Sbjct: 348 WNLLSIVRE 356
>XP_006726695
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   WPLLSIL 7
           WP LS++
Sbjct: 431 WPCLSVI 437
>XP_006721198
          Length = 435

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WPLLSILS 8
           W L+S+LS
Sbjct: 250 WALVSVLS 257
>XP_005269712
          Length = 1800

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W LLSI+ E
Sbjct: 348 WNLLSIVRE 356
>XP_006717788
          Length = 1829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W LLSI+ E
Sbjct: 348 WNLLSIVRE 356
>XP_005269710
          Length = 1834

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W LLSI+ E
Sbjct: 348 WNLLSIVRE 356
>XP_005269709
          Length = 1871

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W LLSI+ E
Sbjct: 348 WNLLSIVRE 356
>XP_005269708
          Length = 1897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W LLSI+ E
Sbjct: 348 WNLLSIVRE 356
>XP_005269706
          Length = 1900

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W LLSI+ E
Sbjct: 348 WNLLSIVRE 356
>XP_005269705
          Length = 1905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W LLSI+ E
Sbjct: 348 WNLLSIVRE 356
>NP_005017
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   WPLLSILS 8
           WP L +LS
Sbjct: 571 WPELPVLS 578
>NP_001273063
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   PLLSILSE 9
           P+LS+L+E
Sbjct: 333 PVLSVLTE 340
>NP_068751
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   PLLSILSE 9
           P+LS+L+E
Sbjct: 333 PVLSVLTE 340
>NP_073563
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1  WPLLSI 6
          WP LSI
Sbjct: 47 WPTLSI 52
>NP_775809
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   WPLLSI 6
           WP LSI
Sbjct: 326 WPTLSI 331
>NP_001258629
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   WPLLSILSE 9
           +P+LSIL++
Sbjct: 181 YPVLSILTQ 189
>NP_060549
          Length = 995

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W ++ +LSE
Sbjct: 212 WDMVQVLSE 220
>NP_919278
          Length = 1925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    WPLLSIL 7
            +PLLSIL
Sbjct: 1105 YPLLSIL 1111
>XP_006721217
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WPLLSILSE 9
          WP +S+L +
Sbjct: 58 WPQVSVLRD 66
>XP_005255871
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WPLLSILSE 9
          WP +S+L +
Sbjct: 58 WPQVSVLRD 66
>XP_006718333
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   PLLSILSE 9
           P+LS+L+E
Sbjct: 223 PVLSVLTE 230
>XP_005253109
          Length = 535

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   PLLSILSE 9
           P+LS+L+E
Sbjct: 337 PVLSVLTE 344
>XP_006716575
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   WPLLSI 6
           WP LSI
Sbjct: 326 WPTLSI 331
>XP_006712459
          Length = 1914

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    WPLLSIL 7
            +PLLSIL
Sbjct: 1094 YPLLSIL 1100
>XP_005264455
          Length = 671

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WPLLSILSE 9
           W ++ +LSE
Sbjct: 212 WDMVQVLSE 220
>XP_006710753
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   WPLLSILS 8
           WP L +LS
Sbjct: 542 WPELPVLS 549
>XP_005263530
          Length = 1043

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   WPLLSILS 8
           WP L +LS
Sbjct: 570 WPELPVLS 577
>XP_006710752
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   WPLLSILS 8
           WP L +LS
Sbjct: 571 WPELPVLS 578
>XP_006710751
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   WPLLSILS 8
           WP L +LS
Sbjct: 571 WPELPVLS 578
>XP_006710750
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   WPLLSILS 8
           WP L +LS
Sbjct: 571 WPELPVLS 578
>XP_006710749
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   WPLLSILS 8
           WP L +LS
Sbjct: 571 WPELPVLS 578
>NP_631913
          Length = 665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WPLLSILSE 9
          WP +S+L +
Sbjct: 58 WPQVSVLRD 66
>NP_001138872
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WPLLSILSE 9
          WP +S+L +
Sbjct: 58 WPQVSVLRD 66
>NP_000042
          Length = 3056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PLLSILSE 9
           PLL ILS+
Sbjct: 434 PLLMILSQ 441
>NP_003030
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WPLLSIL 7
           W LLSI+
Sbjct: 276 WQLLSII 282
>NP_055178
          Length = 4579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    PLLSILSE 9
            P+LS+L E
Sbjct: 1727 PVLSVLKE 1734
>NP_001264984
          Length = 4432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    PLLSILSE 9
            P+LS+L E
Sbjct: 1580 PVLSVLKE 1587
>NP_000253
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WPLLSILS 8
           W +LSIL+
Sbjct: 223 WSVLSILN 230
>NP_997303
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WPLLSIL 7
           W LLSI+
Sbjct: 282 WQLLSII 288
>XP_005261674
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WPLLSILS 8
           W +LSIL+
Sbjct: 102 WSVLSILN 109
>XP_005261673
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WPLLSILS 8
           W +LSIL+
Sbjct: 223 WSVLSILN 230
>XP_005261672
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WPLLSILS 8
           W +LSIL+
Sbjct: 223 WSVLSILN 230
>XP_005266395
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    PLLSILSE 9
            P+LS+L E
Sbjct: 1736 PVLSVLKE 1743
>XP_005271621
          Length = 2708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PLLSILSE 9
          PLL ILS+
Sbjct: 86 PLLMILSQ 93
>XP_006718907
          Length = 3050

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PLLSILSE 9
           PLL ILS+
Sbjct: 434 PLLMILSQ 441
>XP_006718906
          Length = 3056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PLLSILSE 9
           PLL ILS+
Sbjct: 434 PLLMILSQ 441
>XP_005271619
          Length = 3056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PLLSILSE 9
           PLL ILS+
Sbjct: 434 PLLMILSQ 441
>XP_005271618
          Length = 3056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PLLSILSE 9
           PLL ILS+
Sbjct: 434 PLLMILSQ 441
>XP_006710899
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WPLLSIL 7
           W LLSI+
Sbjct: 266 WQLLSII 272
>XP_005263548
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WPLLSIL 7
           W LLSI+
Sbjct: 276 WQLLSII 282
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.138    0.470 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 417,544
Number of extensions: 520
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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