Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     869
NP_001035957                                                           19     869
XP_006721991                                                           19     869
XP_006721990                                                           19     869
XP_006721989                                                           19     869
XP_005258041                                                           19     869
XP_006721988                                                           19     869
XP_006721987                                                           19     869
XP_006721986                                                           19     869
XP_005258040                                                           19     869
XP_006721985                                                           19     869
NP_000032                                                              17    2528
NP_002652                                                              17    2528
NP_001258767                                                           17    2528
NP_001258763                                                           17    2528
NP_057709                                                              17    2528
XP_005258924                                                           17    2528
XP_005247575                                                           17    2528
XP_005247574                                                           17    2528
XP_005247573                                                           17    2528
XP_005247572                                                           17    2528
NP_938146                                                              17    4312
NP_005410                                                              17    4312
XP_006719635                                                           17    4312
XP_005269166                                                           17    4312
XP_005269165                                                           17    4312
NP_644671                                                              16    5631
NP_009330                                                              16    5631
NP_055452                                                              16    5631
NP_001139311                                                           16    5631
NP_060091                                                              16    5631
XP_006716547                                                           16    5631
XP_005250522                                                           16    5631
XP_005250521                                                           16    5631
XP_006712781                                                           16    5631
NP_001139310                                                           16    5631
NP_981951                                                              16    5631
NP_056171                                                              16    7355
NP_874365                                                              16    7355
NP_006720                                                              16    7355
NP_009293                                                              16    7355
NP_115804                                                              16    7355
NP_056057                                                              16    7355
NP_001035207                                                           16    7355
NP_055835                                                              16    7355
NP_001275932                                                           16    7355
NP_001243779                                                           16    7355
NP_596869                                                              16    7355
NP_004454                                                              16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
XP_005263976                                                           16    7355
NP_006579                                                              16    7355
NP_001254479                                                           16    7355
NP_001360                                                              15    9605
NP_003310                                                              15    9605
NP_597676                                                              15    9605
NP_596870                                                              15    9605
NP_699174                                                              15    9605
NP_055335                                                              15    9605
NP_001099008                                                           15    9605
XP_006721637                                                           15    9605
XP_005256849                                                           15    9605
XP_006721482                                                           15    9605
XP_005256470                                                           15    9605
XP_005248319                                                           15    9605
NP_055334                                                              15    9605
NP_597681                                                              15    9605
>NP_000258
          Length = 2818

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1205 FERLVELV 1212
>NP_001035957
          Length = 2839

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1205 FERLVELV 1212
>XP_006721991
          Length = 1632

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1215 FERLVELV 1222
>XP_006721990
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1215 FERLVELV 1222
>XP_006721989
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1215 FERLVELV 1222
>XP_005258041
          Length = 2836

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1205 FERLVELV 1212
>XP_006721988
          Length = 2846

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1215 FERLVELV 1222
>XP_006721987
          Length = 2849

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1215 FERLVELV 1222
>XP_006721986
          Length = 2854

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1202 FERLVELV 1209
>XP_005258040
          Length = 2857

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1205 FERLVELV 1212
>XP_006721985
          Length = 2867

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FERLVELV 9
            FERLVELV
Sbjct: 1215 FERLVELV 1222
>NP_000032
          Length = 317

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   WFERLVE 7
           WFE LVE
Sbjct: 282 WFEPLVE 288
>NP_002652
          Length = 1265

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   WFERLVELV 9
           +FE LVELV
Sbjct: 709 YFESLVELV 717
>NP_001258767
          Length = 334

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WFERLVEL 8
           WF+RL+ L
Sbjct: 316 WFKRLIAL 323
>NP_001258763
          Length = 276

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WFERLVEL 8
           WF+RL+ L
Sbjct: 258 WFKRLIAL 265
>NP_057709
          Length = 334

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WFERLVEL 8
           WF+RL+ L
Sbjct: 316 WFKRLIAL 323
>XP_005258924
          Length = 343

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   WFERLVE 7
           WFE LVE
Sbjct: 308 WFEPLVE 314
>XP_005247575
          Length = 336

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WFERLVEL 8
           WF+RL+ L
Sbjct: 318 WFKRLIAL 325
>XP_005247574
          Length = 336

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WFERLVEL 8
           WF+RL+ L
Sbjct: 318 WFKRLIAL 325
>XP_005247573
          Length = 336

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WFERLVEL 8
           WF+RL+ L
Sbjct: 318 WFKRLIAL 325
>XP_005247572
          Length = 336

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WFERLVEL 8
           WF+RL+ L
Sbjct: 318 WFKRLIAL 325
>NP_938146
          Length = 847

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   WFERLVELV 9
           W ++++ELV
Sbjct: 552 WLDKILELV 560
>NP_005410
          Length = 851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   WFERLVELV 9
           W ++++ELV
Sbjct: 556 WLDKILELV 564
>XP_006719635
          Length = 652

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   WFERLVELV 9
           W ++++ELV
Sbjct: 624 WLDKILELV 632
>XP_005269166
          Length = 915

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   WFERLVELV 9
           W ++++ELV
Sbjct: 620 WLDKILELV 628
>XP_005269165
          Length = 919

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   WFERLVELV 9
           W ++++ELV
Sbjct: 624 WLDKILELV 632
>NP_644671
          Length = 712

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WFERLVELV 9
           W E ++EL+
Sbjct: 557 WIESILELI 565
>NP_009330
          Length = 750

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WFERLVELV 9
           W E ++EL+
Sbjct: 557 WIESILELI 565
>NP_055452
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WFERLVELV 9
          W +RL+ +V
Sbjct: 4  WIKRLIRMV 12
>NP_001139311
          Length = 348

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WFERLVELV 9
          W +RL+ +V
Sbjct: 4  WIKRLIRMV 12
>NP_060091
          Length = 302

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WFERLVEL 8
           W ERLV L
Sbjct: 176 WGERLVSL 183
>XP_006716547
          Length = 348

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WFERLVELV 9
          W +RL+ +V
Sbjct: 4  WIKRLIRMV 12
>XP_005250522
          Length = 164

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  WFERLVEL 8
          W ERLV L
Sbjct: 38 WGERLVSL 45
>XP_005250521
          Length = 229

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WFERLVEL 8
           W ERLV L
Sbjct: 103 WGERLVSL 110
>XP_006712781
          Length = 750

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WFERLVELV 9
           W E ++EL+
Sbjct: 557 WIESILELI 565
>NP_001139310
          Length = 300

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WFERLVELV 9
          W +RL+ +V
Sbjct: 4  WIKRLIRMV 12
>NP_981951
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ERLVELV 9
           ERL+ELV
Sbjct: 213 ERLIELV 219
>NP_056171
          Length = 1630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFERLVE 7
           W ER+VE
Sbjct: 812 WRERMVE 818
>NP_874365
          Length = 1655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFERLVE 7
           W ER+VE
Sbjct: 812 WRERMVE 818
>NP_006720
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FERLVELV 9
           F RL+ELV
Sbjct: 830 FNRLLELV 837
>NP_009293
          Length = 1096

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FERLVELV 9
           F RL+ELV
Sbjct: 830 FNRLLELV 837
>NP_115804
          Length = 1810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ERLVELV 9
           ERL+EL+
Sbjct: 110 ERLIELI 116
>NP_056057
          Length = 1205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   WFERLVEL 8
           W E L+EL
Sbjct: 352 WTETLIEL 359
>NP_001035207
          Length = 1450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   WFERLVEL 8
           W E L+EL
Sbjct: 597 WTETLIEL 604
>NP_055835
          Length = 1323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WFERLVEL 8
           W ERLV L
Sbjct: 169 WAERLVVL 176
>NP_001275932
          Length = 1256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WFERLVEL 8
           W ERLV L
Sbjct: 169 WAERLVVL 176
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    WFERLVELV 9
            WF+  VELV
Sbjct: 6290 WFKDDVELV 6298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    WFERLVEL 8
            WF + VE+
Sbjct: 2827 WFHKSVEI 2834
>NP_596869
          Length = 33423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    WFERLVELV 9
            WF+  VELV
Sbjct: 5363 WFKDDVELV 5371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    WFERLVEL 8
            WF + VE+
Sbjct: 2827 WFHKSVEI 2834
>NP_004454
          Length = 961

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FERLVELV 9
           F+R VELV
Sbjct: 474 FDRAVELV 481
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    WFERLVELV 9
            WF+  VELV
Sbjct: 6291 WFKDDVELV 6299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    WFERLVEL 8
            WF + VE+
Sbjct: 2828 WFHKSVEI 2835
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    WFERLVELV 9
            WF+  VELV
Sbjct: 6291 WFKDDVELV 6299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    WFERLVEL 8
            WF + VE+
Sbjct: 2828 WFHKSVEI 2835
>XP_005263976
          Length = 227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WFERLVELV 9
          W + +VEL+
Sbjct: 60 WTQEIVELI 68
>NP_006579
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WFERLVELV 9
          W + +VEL+
Sbjct: 60 WTQEIVELI 68
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    WFERLVELV 9
            WF+  VELV
Sbjct: 6607 WFKDDVELV 6615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    WFERLVEL 8
            WF + VE+
Sbjct: 2827 WFHKSVEI 2834
>NP_001360
          Length = 4624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1    WFERLVE 7
            WF  L+E
Sbjct: 4457 WFTELIE 4463
>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    WFERLVEL 8
            WF + VE+
Sbjct: 2781 WFHKSVEI 2788
>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    WFERLVEL 8
            WF + VE+
Sbjct: 2781 WFHKSVEI 2788
>NP_596870
          Length = 5604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    WFERLVEL 8
            WF + VE+
Sbjct: 2827 WFHKSVEI 2834
>NP_699174
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 7/8 (87%)

Query: 1   WFERLVEL 8
           W ++++EL
Sbjct: 248 WMDKVIEL 255
>NP_055335
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WFERLVELV 9
           W E LVE++
Sbjct: 647 WVEVLVEIL 655
>NP_001099008
          Length = 1332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WFERLVELV 9
           W E LVE++
Sbjct: 647 WVEVLVEIL 655
>XP_006721637
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WFERLVELV 9
          W+E   ELV
Sbjct: 16 WYEPSAELV 24
>XP_005256849
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WFERLVELV 9
          W+E   ELV
Sbjct: 16 WYEPSAELV 24
>XP_006721482
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WFERLVELV 9
           W E LVE++
Sbjct: 647 WVEVLVEIL 655
>XP_005256470
          Length = 1120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WFERLVELV 9
           W E LVE++
Sbjct: 647 WVEVLVEIL 655
>XP_005248319
          Length = 4609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1    WFERLVE 7
            WF  L+E
Sbjct: 4442 WFTELIE 4448
>NP_055334
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WFERLVELV 9
          W+E   ELV
Sbjct: 16 WYEPSAELV 24
>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    WFERLVEL 8
            WF + VE+
Sbjct: 2781 WFHKSVEI 2788
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.149    0.535 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 453,126
Number of extensions: 1053
Number of successful extensions: 73
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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