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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000224                                                              18    1135
NP_000360                                                              18    1135
XP_005268094                                                           18    1135
XP_005264366                                                           18    1135
XP_006712078                                                           18    1135
NP_002021                                                              17    4312
NP_001073866                                                           16    7355
NP_036507                                                              16    7355
NP_005056                                                              15    9605
NP_004161                                                              15    9605
NP_003050                                                              15    9605
NP_001035292                                                           15    9605
NP_001157844                                                           15    9605
NP_848658                                                              15    9605
NP_068593                                                              15    9605
XP_005268046                                                           15    9605
XP_005268045                                                           15    9605
XP_006716026                                                           15    9605
XP_006716025                                                           15    9605
XP_006716024                                                           15    9605
XP_005262827                                                           15    9605
XP_006714170                                                           15    9605
XP_006714169                                                           15    9605
XP_006714168                                                           15    9605
XP_005262826                                                           15    9605
XP_006714167                                                           15    9605
XP_006710297                                                           15    9605

>NP_000224
          Length = 699

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY LTVITL
Sbjct: 454 VYTLTVITL 462




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY+LT++ L
Sbjct: 526 VYILTILIL 534



>NP_000360
          Length = 764

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY LTVITL
Sbjct: 509 VYTLTVITL 517



>XP_005268094
          Length = 764

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY LTVITL
Sbjct: 509 VYTLTVITL 517



>XP_005264366
          Length = 380

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY LTVITL
Sbjct: 135 VYTLTVITL 143




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY+LT++ L
Sbjct: 207 VYILTILIL 215



>XP_006712078
          Length = 389

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY LTVITL
Sbjct: 144 VYTLTVITL 152




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY+LT++ L
Sbjct: 216 VYILTILIL 224



>NP_002021
          Length = 353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY++T+I L
Sbjct: 113 VYLITIIAL 121



>NP_001073866
          Length = 782

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VYMLTVITL 9
           +Y+ T +TL
Sbjct: 303 IYLFTAVTL 311



>NP_036507
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  VYMLTVITL 9
          VYM +V+TL
Sbjct: 8  VYMPSVLTL 16



>NP_005056
          Length = 794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           +Y++T+I L
Sbjct: 745 LYLMTIIAL 753



>NP_004161
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VYMLTVIT 8
           +YM TV+T
Sbjct: 284 LYMATVLT 291



>NP_003050
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VYMLTVIT 8
           VY+ TV+T
Sbjct: 123 VYLSTVVT 130



>NP_001035292
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY++TV+ +
Sbjct: 173 VYLITVLAM 181



>NP_001157844
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VYMLTVIT 8
          +Y+L+VIT
Sbjct: 47 LYLLSVIT 54



>NP_848658
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VYMLTVIT 8
           VY+LT+ T
Sbjct: 337 VYILTITT 344



>NP_068593
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VYMLTVI 7
           VY+LTV+
Sbjct: 223 VYLLTVL 229



>XP_005268046
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           +Y++T+I L
Sbjct: 722 LYLMTIIAL 730



>XP_005268045
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           +Y++T+I L
Sbjct: 724 LYLMTIIAL 732



>XP_006716026
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VYMLTVIT 8
           VY+LT+ T
Sbjct: 337 VYILTITT 344



>XP_006716025
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VYMLTVIT 8
           VY+LT+ T
Sbjct: 337 VYILTITT 344



>XP_006716024
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VYMLTVIT 8
           VY+LT+ T
Sbjct: 337 VYILTITT 344



>XP_005262827
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY++TV+ +
Sbjct: 173 VYLITVLAM 181



>XP_006714170
          Length = 274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY++TV+ +
Sbjct: 173 VYLITVLAM 181



>XP_006714169
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY++TV+ +
Sbjct: 173 VYLITVLAM 181



>XP_006714168
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY++TV+ +
Sbjct: 173 VYLITVLAM 181



>XP_005262826
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY++TV+ +
Sbjct: 173 VYLITVLAM 181



>XP_006714167
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYMLTVITL 9
           VY++TV+ +
Sbjct: 173 VYLITVLAM 181



>XP_006710297
          Length = 350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   VYMLTVI 7
           +YMLT++
Sbjct: 334 IYMLTIM 340



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.149    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 322,434
Number of extensions: 614
Number of successful extensions: 30
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)