Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              18    1482
NP_005913                                                              18    1482
XP_005267046                                                           18    1482
XP_005267045                                                           18    1482
NP_000611                                                              18    1935
NP_001191147                                                           18    1935
NP_001191142                                                           18    1935
NP_001191143                                                           18    1935
XP_006719491                                                           18    1935
XP_006719490                                                           18    1935
XP_006719489                                                           18    1935
NP_055956                                                              17    4312
NP_003513                                                              17    4312
NP_003517                                                              17    4312
NP_006243                                                              17    4312
NP_115502                                                              17    4312
NP_001164194                                                           17    4312
NP_001164193                                                           17    4312
NP_001019770                                                           17    4312
NP_001164195                                                           17    4312
NP_001154806                                                           17    4312
NP_001137359                                                           17    4312
NP_004227                                                              17    4312
NP_066407                                                              17    4312
NP_619790                                                              17    4312
NP_542160                                                              17    4312
XP_006726868                                                           17    4312
XP_006723981                                                           17    4312
XP_005249096                                                           17    4312
XP_005265040                                                           17    4312
XP_006713131                                                           17    4312
XP_006711400                                                           17    4312
XP_006711399                                                           17    4312
XP_006711398                                                           17    4312
XP_006710322                                                           17    4312
NP_003511                                                              17    4312
NP_778225                                                              17    4312
NP_003510                                                              17    4312
NP_066406                                                              17    4312
NP_003519                                                              17    4312
NP_066402                                                              17    4312
NP_003512                                                              17    4312
NP_003518                                                              17    4312
NP_003514                                                              17    4312
NP_003516                                                              17    4312
NP_003509                                                              17    4312
NP_003515                                                              17    4312
NP_733759                                                              16    5631
NP_001275514                                                           16    5631
NP_741982                                                              16    5631
NP_116246                                                              16    5631
XP_005254200                                                           16    5631
NP_000127                                                              16    7355
NP_002196                                                              16    7355
NP_001265852                                                           16    7355
NP_001265853                                                           16    7355
NP_001092315                                                           16    7355
NP_001230672                                                           16    7355
NP_001258631                                                           16    7355
NP_001230673                                                           16    7355
NP_001035173                                                           16    7355
NP_542164                                                              16    7355
NP_071423                                                              16    7355
XP_006726581                                                           16    7355
XP_006722446                                                           16    7355
XP_006722445                                                           16    7355
XP_006722444                                                           16    7355
XP_006722443                                                           16    7355
XP_006718014                                                           16    7355
XP_006717067                                                           16    7355
XP_006717066                                                           16    7355
XP_006717065                                                           16    7355
XP_006717064                                                           16    7355
XP_005272100                                                           16    7355
NP_006764                                                              16    7355
>NP_006715
          Length = 1558

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYKALKQMG 9
           V KALKQMG
Sbjct: 530 VDKALKQMG 538
>NP_005913
          Length = 1608

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYKALKQMG 9
           V KALKQMG
Sbjct: 530 VDKALKQMG 538
>XP_005267046
          Length = 1554

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYKALKQMG 9
           V KALKQMG
Sbjct: 530 VDKALKQMG 538
>XP_005267045
          Length = 1604

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYKALKQMG 9
           V KALKQMG
Sbjct: 530 VDKALKQMG 538
>NP_000611
          Length = 1434

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VYKALKQMG 9
            VY+ALK+ G
Sbjct: 1340 VYRALKEQG 1348
>NP_001191147
          Length = 1468

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VYKALKQMG 9
            VY+ALK+ G
Sbjct: 1374 VYRALKEQG 1382
>NP_001191142
          Length = 1098

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VYKALKQMG 9
            VY+ALK+ G
Sbjct: 1004 VYRALKEQG 1012
>NP_001191143
          Length = 1098

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VYKALKQMG 9
            VY+ALK+ G
Sbjct: 1004 VYRALKEQG 1012
>XP_006719491
          Length = 1434

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VYKALKQMG 9
            VY+ALK+ G
Sbjct: 1340 VYRALKEQG 1348
>XP_006719490
          Length = 1468

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VYKALKQMG 9
            VY+ALK+ G
Sbjct: 1374 VYRALKEQG 1382
>XP_006719489
          Length = 1468

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VYKALKQMG 9
            VY+ALK+ G
Sbjct: 1374 VYRALKEQG 1382
>NP_055956
          Length = 351

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VYKALKQMG 9
           VY+ LKQ G
Sbjct: 308 VYRILKQKG 316
>NP_003513
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_003517
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_006243
          Length = 552

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VYKALKQM 8
           VY+A+KQ+
Sbjct: 419 VYRAMKQL 426
>NP_115502
          Length = 233

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  YKALKQMG 9
          YKA+KQ G
Sbjct: 34 YKAVKQEG 41
>NP_001164194
          Length = 212

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  YKALKQMG 9
          YKA+KQ G
Sbjct: 34 YKAVKQEG 41
>NP_001164193
          Length = 215

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  YKALKQMG 9
          YKA+KQ G
Sbjct: 42 YKAVKQEG 49
>NP_001019770
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_001164195
          Length = 207

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  YKALKQMG 9
          YKA+KQ G
Sbjct: 34 YKAVKQEG 41
>NP_001154806
          Length = 134

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_001137359
          Length = 450

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  YKALKQM 8
          +KALKQM
Sbjct: 69 FKALKQM 75
>NP_004227
          Length = 443

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  YKALKQM 8
          +KALKQM
Sbjct: 69 FKALKQM 75
>NP_066407
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_619790
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_542160
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>XP_006726868
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>XP_006723981
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>XP_005249096
          Length = 150

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 66 VYKVLKQV 73
>XP_005265040
          Length = 273

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VYKALKQMG 9
           VY+ LKQ G
Sbjct: 230 VYRILKQKG 238
>XP_006713131
          Length = 304

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VYKALKQMG 9
           VY+ LKQ G
Sbjct: 261 VYRILKQKG 269
>XP_006711400
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>XP_006711399
          Length = 128

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>XP_006711398
          Length = 147

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>XP_006710322
          Length = 657

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VYKALKQMG 9
           +Y+ LK MG
Sbjct: 462 IYQGLKDMG 470
>NP_003511
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_778225
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_003510
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_066406
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_003519
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_066402
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_003512
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_003518
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_003514
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_003516
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_003509
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_003515
          Length = 126

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          VYK LKQ+
Sbjct: 42 VYKVLKQV 49
>NP_733759
          Length = 127

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  VYKALKQM 8
          +YK LKQ+
Sbjct: 43 IYKVLKQV 50
>NP_001275514
          Length = 332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   YKALKQM 8
           YKALK M
Sbjct: 236 YKALKMM 242
>NP_741982
          Length = 373

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   YKALKQM 8
           YKALK M
Sbjct: 236 YKALKMM 242
>NP_116246
          Length = 547

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   YKALKQM 8
           YKALK M
Sbjct: 236 YKALKMM 242
>XP_005254200
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   YKALKQM 8
           YKALK M
Sbjct: 236 YKALKMM 242
>NP_000127
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VYKALKQM 8
          +Y+ALK+M
Sbjct: 48 MYEALKEM 55
>NP_002196
          Length = 1049

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VYKALK 6
           VYKALK
Sbjct: 960 VYKALK 965
>NP_001265852
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VYKALKQMG 9
          +YKA+K +G
Sbjct: 30 LYKAMKGIG 38
>NP_001265853
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VYKALKQMG 9
          +YKA+K +G
Sbjct: 30 LYKAMKGIG 38
>NP_001092315
          Length = 327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VYKALKQMG 9
          +YKA+K +G
Sbjct: 30 LYKAMKGIG 38
>NP_001230672
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VYKALKQM 8
          +Y+ALK+M
Sbjct: 48 MYEALKEM 55
>NP_001258631
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VYKALKQMG 9
          +YKA+K +G
Sbjct: 30 LYKAMKGIG 38
>NP_001230673
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VYKALKQM 8
          +Y+ALK+M
Sbjct: 48 MYEALKEM 55
>NP_001035173
          Length = 327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VYKALKQMG 9
          +YKA+K +G
Sbjct: 30 LYKAMKGIG 38
>NP_542164
          Length = 950

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VYKALKQ 7
           +YKALK+
Sbjct: 231 IYKALKR 237
>NP_071423
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VYKALKQMG 9
           VYK  KQ+G
Sbjct: 232 VYKNKKQVG 240
>XP_006726581
          Length = 305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VYKALKQMG 9
          +YKA+K +G
Sbjct: 30 LYKAMKGIG 38
>XP_006722446
          Length = 889

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VYKALKQ 7
           +YKALK+
Sbjct: 231 IYKALKR 237
>XP_006722445
          Length = 905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VYKALKQ 7
           +YKALK+
Sbjct: 231 IYKALKR 237
>XP_006722444
          Length = 914

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VYKALKQ 7
           +YKALK+
Sbjct: 231 IYKALKR 237
>XP_006722443
          Length = 925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VYKALKQ 7
           +YKALK+
Sbjct: 206 IYKALKR 212
>XP_006718014
          Length = 351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VYKALKQMG 9
          +YKA+K +G
Sbjct: 54 LYKAMKGIG 62
>XP_006717067
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VYKALKQM 8
          +Y+ALK+M
Sbjct: 48 MYEALKEM 55
>XP_006717066
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VYKALKQM 8
          +Y+ALK+M
Sbjct: 48 MYEALKEM 55
>XP_006717065
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VYKALKQM 8
          +Y+ALK+M
Sbjct: 48 MYEALKEM 55
>XP_006717064
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VYKALKQM 8
          +Y+ALK+M
Sbjct: 48 MYEALKEM 55
>XP_005272100
          Length = 658

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VYKALKQMG 9
           VYK  KQ+G
Sbjct: 232 VYKNKKQVG 240
>NP_006764
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KALKQMG 9
           KA+K+MG
Sbjct: 192 KAIKEMG 198
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.134    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 410,872
Number of extensions: 935
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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