Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1135
XP_006718908                                                           18    1135
XP_005271621                                                           18    1135
XP_006718907                                                           18    1135
XP_006718906                                                           18    1135
XP_005271619                                                           18    1135
XP_005271618                                                           18    1135
NP_001243353                                                           16    7355
NP_000846                                                              16    7355
NP_001230075                                                           15    9605
NP_002524                                                              15    9605
NP_001230076                                                           15    9605
NP_996671                                                              15    9605
NP_872332                                                              15    9605
XP_006720125                                                           15    9605
XP_005267432                                                           15    9605
XP_005267431                                                           15    9605
XP_005267430                                                           15    9605
XP_006711841                                                           15    9605
XP_006711840                                                           15    9605
XP_006711839                                                           15    9605
XP_006711838                                                           15    9605
XP_006711837                                                           15    9605
XP_006711836                                                           15    9605
XP_006711835                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VVERVLMRL 9
            V ERVLMRL
Sbjct: 3005 VAERVLMRL 3013
>XP_006718908
          Length = 1708

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VVERVLMRL 9
            V ERVLMRL
Sbjct: 1657 VAERVLMRL 1665
>XP_005271621
          Length = 2708

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VVERVLMRL 9
            V ERVLMRL
Sbjct: 2657 VAERVLMRL 2665
>XP_006718907
          Length = 3050

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VVERVLMRL 9
            V ERVLMRL
Sbjct: 2999 VAERVLMRL 3007
>XP_006718906
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VVERVLMRL 9
            V ERVLMRL
Sbjct: 3005 VAERVLMRL 3013
>XP_005271619
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VVERVLMRL 9
            V ERVLMRL
Sbjct: 3005 VAERVLMRL 3013
>XP_005271618
          Length = 3056

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VVERVLMRL 9
            V ERVLMRL
Sbjct: 3005 VAERVLMRL 3013
>NP_001243353
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ERVLMRL 9
           ERVL+RL
Sbjct: 376 ERVLLRL 382
>NP_000846
          Length = 732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ERVLMRL 9
           ERVL+RL
Sbjct: 376 ERVLLRL 382
>NP_001230075
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 297 VNRVLMKL 304
>NP_002524
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 486 VNRVLMKL 493
>NP_001230076
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 395 VNRVLMKL 402
>NP_996671
          Length = 750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 380 VNRVLMKL 387
>NP_872332
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VVERVLMRL 9
          +VER+ +RL
Sbjct: 59 IVERMYLRL 67
>XP_006720125
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VVERVLMRL 9
          +VER+ +RL
Sbjct: 59 IVERMYLRL 67
>XP_005267432
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VVERVLMRL 9
          +VER+ +RL
Sbjct: 59 IVERMYLRL 67
>XP_005267431
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VVERVLMRL 9
          +VER+ +RL
Sbjct: 59 IVERMYLRL 67
>XP_005267430
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VVERVLMRL 9
          +VER+ +RL
Sbjct: 59 IVERMYLRL 67
>XP_006711841
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 222 VNRVLMKL 229
>XP_006711840
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 270 VNRVLMKL 277
>XP_006711839
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 486 VNRVLMKL 493
>XP_006711838
          Length = 728

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 486 VNRVLMKL 493
>XP_006711837
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 368 VNRVLMKL 375
>XP_006711836
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 368 VNRVLMKL 375
>XP_006711835
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERVLMRL 9
           V RVLM+L
Sbjct: 486 VNRVLMKL 493
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.348    0.155    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 316,032
Number of extensions: 341
Number of successful extensions: 25
Number of sequences better than 10000.0: 25
Number of HSP's gapped: 25
Number of HSP's successfully gapped: 25
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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