Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001129971                                                           17    2528
XP_006723227                                                           17    2528
NP_000349                                                              17    4312
NP_619639                                                              17    4312
NP_733842                                                              17    4312
NP_060338                                                              17    4312
NP_573403                                                              17    4312
NP_877496                                                              17    4312
XP_005260559                                                           17    4312
XP_005260558                                                           17    4312
XP_006723918                                                           17    4312
XP_005260557                                                           17    4312
XP_005260556                                                           17    4312
XP_005260555                                                           17    4312
XP_005260554                                                           17    4312
XP_006723917                                                           17    4312
XP_005260553                                                           17    4312
XP_005271664                                                           17    4312
XP_006718929                                                           17    4312
XP_005271663                                                           17    4312
XP_005271662                                                           17    4312
XP_005271661                                                           17    4312
XP_005271660                                                           17    4312
NP_001073379                                                           16    5631
NP_055789                                                              16    5631
NP_001096127                                                           16    5631
XP_006719697                                                           16    5631
XP_006719696                                                           16    5631
XP_006719695                                                           16    5631
XP_005269238                                                           16    5631
XP_005252486                                                           16    5631
XP_005252485                                                           16    5631
XP_005252484                                                           16    5631
XP_005252483                                                           16    5631
NP_001272390                                                           16    7355
NP_006624                                                              16    7355
NP_001272391                                                           16    7355
NP_001272389                                                           16    7355
NP_001275563                                                           16    7355
NP_060652                                                              16    7355
NP_001275567                                                           16    7355
NP_001070966                                                           16    7355
NP_003464                                                              16    7355
NP_001275560                                                           16    7355
NP_001275562                                                           16    7355
NP_001275565                                                           16    7355
NP_001275566                                                           16    7355
NP_001275569                                                           16    7355
NP_001275561                                                           16    7355
NP_001275568                                                           16    7355
NP_001275564                                                           16    7355
NP_998768                                                              16    7355
NP_958934                                                              16    7355
NP_001182457                                                           16    7355
XP_006722034                                                           16    7355
XP_005252660                                                           16    7355
XP_006715993                                                           16    7355
XP_006715992                                                           16    7355
XP_005250338                                                           16    7355
XP_005248471                                                           16    7355
XP_005248470                                                           16    7355
XP_006714585                                                           16    7355
XP_005248468                                                           16    7355
XP_005248467                                                           16    7355
XP_005248466                                                           16    7355
NP_005536                                                              16    7355
NP_031363                                                              15    9605
NP_031361                                                              15    9605
XP_006713504                                                           15    9605
XP_006713503                                                           15    9605
XP_005265688                                                           15    9605
XP_006713502                                                           15    9605
XP_006713501                                                           15    9605
XP_006713500                                                           15    9605
XP_005265687                                                           15    9605
>NP_001129971
          Length = 924

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS+LLNH
Sbjct: 805 RSILLNH 811
>XP_006723227
          Length = 868

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS+LLNH
Sbjct: 749 RSILLNH 755
>NP_000349
          Length = 683

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TRSLLLNH 9
           TR+LL NH
Sbjct: 431 TRNLLRNH 438
>NP_619639
          Length = 4074

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    VTRSLLLNH 9
            VT SLLL H
Sbjct: 2438 VTDSLLLGH 2446
>NP_733842
          Length = 3396

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    VTRSLLLNH 9
            VT SLLL H
Sbjct: 2438 VTDSLLLGH 2446
>NP_060338
          Length = 705

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RSL++NH
Sbjct: 374 RSLIINH 380
>NP_573403
          Length = 720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS++LNH
Sbjct: 264 RSIILNH 270
>NP_877496
          Length = 720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS++LNH
Sbjct: 264 RSIILNH 270
>XP_005260559
          Length = 537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RSLLLNH 9
          RS++LNH
Sbjct: 81 RSIILNH 87
>XP_005260558
          Length = 537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RSLLLNH 9
          RS++LNH
Sbjct: 81 RSIILNH 87
>XP_006723918
          Length = 632

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS++LNH
Sbjct: 176 RSIILNH 182
>XP_005260557
          Length = 632

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS++LNH
Sbjct: 176 RSIILNH 182
>XP_005260556
          Length = 632

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS++LNH
Sbjct: 176 RSIILNH 182
>XP_005260555
          Length = 632

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS++LNH
Sbjct: 176 RSIILNH 182
>XP_005260554
          Length = 632

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS++LNH
Sbjct: 176 RSIILNH 182
>XP_006723917
          Length = 720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS++LNH
Sbjct: 264 RSIILNH 270
>XP_005260553
          Length = 720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS++LNH
Sbjct: 264 RSIILNH 270
>XP_005271664
          Length = 732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RSL++NH
Sbjct: 374 RSLIINH 380
>XP_006718929
          Length = 756

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RSL++NH
Sbjct: 374 RSLIINH 380
>XP_005271663
          Length = 774

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RSL++NH
Sbjct: 374 RSLIINH 380
>XP_005271662
          Length = 777

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RSL++NH
Sbjct: 374 RSLIINH 380
>XP_005271661
          Length = 777

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RSL++NH
Sbjct: 374 RSLIINH 380
>XP_005271660
          Length = 777

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RSL++NH
Sbjct: 374 RSLIINH 380
>NP_001073379
          Length = 1722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VTRSLLLNH 9
            +T SLL NH
Sbjct: 1319 MTNSLLRNH 1327
>NP_055789
          Length = 1556

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRSLLLNH 9
           VTR+ LL H
Sbjct: 512 VTRTALLTH 520
>NP_001096127
          Length = 936

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RSLLLNH 9
           RS+L+NH
Sbjct: 818 RSILVNH 824
>XP_006719697
          Length = 1658

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VTRSLLLNH 9
            +T SLL NH
Sbjct: 1255 MTNSLLRNH 1263
>XP_006719696
          Length = 1696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VTRSLLLNH 9
            +T SLL NH
Sbjct: 1255 MTNSLLRNH 1263
>XP_006719695
          Length = 1696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VTRSLLLNH 9
            +T SLL NH
Sbjct: 1255 MTNSLLRNH 1263
>XP_005269238
          Length = 1696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VTRSLLLNH 9
            +T SLL NH
Sbjct: 1255 MTNSLLRNH 1263
>XP_005252486
          Length = 1407

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRSLLLNH 9
           VTR+ LL H
Sbjct: 353 VTRTALLTH 361
>XP_005252485
          Length = 1622

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRSLLLNH 9
           VTR+ LL H
Sbjct: 568 VTRTALLTH 576
>XP_005252484
          Length = 1566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRSLLLNH 9
           VTR+ LL H
Sbjct: 512 VTRTALLTH 520
>XP_005252483
          Length = 1612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRSLLLNH 9
           VTR+ LL H
Sbjct: 568 VTRTALLTH 576
>NP_001272390
          Length = 1071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TRSLLLNH 9
           T SLLL H
Sbjct: 714 THSLLLEH 721
>NP_006624
          Length = 1575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    TRSLLLNH 9
            T SLLL H
Sbjct: 1218 THSLLLEH 1225
>NP_001272391
          Length = 1071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TRSLLLNH 9
           T SLLL H
Sbjct: 714 THSLLLEH 721
>NP_001272389
          Length = 1525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    TRSLLLNH 9
            T SLLL H
Sbjct: 1168 THSLLLEH 1175
>NP_001275563
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_060652
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_001275567
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 170 ISRSLLIN 177
>NP_001070966
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_003464
          Length = 540

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TRSLLLNH 9
           T SLL NH
Sbjct: 201 TSSLLTNH 208
>NP_001275560
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 300 ISRSLLIN 307
>NP_001275562
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_001275565
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 170 ISRSLLIN 177
>NP_001275566
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 170 ISRSLLIN 177
>NP_001275569
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 170 ISRSLLIN 177
>NP_001275561
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_001275568
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 170 ISRSLLIN 177
>NP_001275564
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_998768
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RSLLLNH 9
           RSLLL H
Sbjct: 185 RSLLLGH 191
>NP_958934
          Length = 428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RSLLLNH 9
           RSL LNH
Sbjct: 149 RSLQLNH 155
>NP_001182457
          Length = 382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RSLLLNH 9
           RSL LNH
Sbjct: 145 RSLQLNH 151
>XP_006722034
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VTRSLLLN 8
           ++RSLL+N
Sbjct: 300 ISRSLLIN 307
>XP_005252660
          Length = 490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TRSLLLNH 9
           T SLL NH
Sbjct: 151 TSSLLTNH 158
>XP_006715993
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  RSLLLNH 9
          RSLLL H
Sbjct: 90 RSLLLGH 96
>XP_006715992
          Length = 387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RSLLLNH 9
           RSLLL H
Sbjct: 147 RSLLLGH 153
>XP_005250338
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RSLLLNH 9
           RSLLL H
Sbjct: 178 RSLLLGH 184
>XP_005248471
          Length = 1128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TRSLLLNH 9
           T SLLL H
Sbjct: 771 THSLLLEH 778
>XP_005248470
          Length = 1518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    TRSLLLNH 9
            T SLLL H
Sbjct: 1161 THSLLLEH 1168
>XP_006714585
          Length = 1525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    TRSLLLNH 9
            T SLLL H
Sbjct: 1168 THSLLLEH 1175
>XP_005248468
          Length = 1548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    TRSLLLNH 9
            T SLLL H
Sbjct: 1191 THSLLLEH 1198
>XP_005248467
          Length = 1548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    TRSLLLNH 9
            T SLLL H
Sbjct: 1191 THSLLLEH 1198
>XP_005248466
          Length = 1565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    TRSLLLNH 9
            T SLLL H
Sbjct: 1208 THSLLLEH 1215
>NP_005536
          Length = 428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RSLLLNH 9
           RSL LNH
Sbjct: 149 RSLQLNH 155
>NP_031363
          Length = 1778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VTRSLLLNH 9
            VTR+L LN+
Sbjct: 1273 VTRTLRLNN 1281
>NP_031361
          Length = 1755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VTRSLLLNH 9
            VTR+L LN+
Sbjct: 1273 VTRTLRLNN 1281
>XP_006713504
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTRSLLLNH 9
           VTR+L LN+
Sbjct: 573 VTRTLRLNN 581
>XP_006713503
          Length = 1438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VTRSLLLNH 9
            VTR+L LN+
Sbjct: 1276 VTRTLRLNN 1284
>XP_005265688
          Length = 1480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTRSLLLNH 9
           VTR+L LN+
Sbjct: 975 VTRTLRLNN 983
>XP_006713502
          Length = 1578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VTRSLLLNH 9
            VTR+L LN+
Sbjct: 1276 VTRTLRLNN 1284
>XP_006713501
          Length = 1727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VTRSLLLNH 9
            VTR+L LN+
Sbjct: 1276 VTRTLRLNN 1284
>XP_006713500
          Length = 1746

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VTRSLLLNH 9
            VTR+L LN+
Sbjct: 1241 VTRTLRLNN 1249
>XP_005265687
          Length = 1758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VTRSLLLNH 9
            VTR+L LN+
Sbjct: 1276 VTRTLRLNN 1284
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.136    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 393,495
Number of extensions: 744
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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