Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001013433                                                           19     665
NP_060785                                                              19     665
NP_361014                                                              19     665
NP_001171868                                                           18    1935
NP_065960                                                              18    1935
NP_001171866                                                           18    1935
NP_001171867                                                           18    1935
XP_006712716                                                           18    1935
XP_005263777                                                           18    1935
XP_005263776                                                           18    1935
XP_006712715                                                           18    1935
XP_006712714                                                           18    1935
NP_060903                                                              17    3301
NP_001140160                                                           17    3301
NP_001171864                                                           17    3301
NP_053586                                                              17    3301
NP_053584                                                              17    3301
NP_004874                                                              17    3301
NP_053585                                                              17    3301
NP_001036083                                                           17    3301
NP_005475                                                              17    3301
XP_005267304                                                           17    3301
XP_006714873                                                           17    3301
XP_006714872                                                           17    3301
XP_006714871                                                           17    3301
NP_055661                                                              17    4312
XP_005251177                                                           17    4312
NP_919290                                                              16    5631
NP_055619                                                              16    5631
XP_005257995                                                           16    5631
XP_005257994                                                           16    5631
XP_006721674                                                           16    5631
XP_006721673                                                           16    5631
XP_006721672                                                           16    5631
XP_005256939                                                           16    5631
XP_005256938                                                           16    5631
XP_005249698                                                           16    5631
NP_001129396                                                           16    5631
NP_001273                                                              16    5631
NP_001025177                                                           16    5631
NP_068602                                                              16    7355
NP_001157285                                                           16    7355
NP_056078                                                              16    7355
NP_001167587                                                           16    7355
NP_001167588                                                           16    7355
NP_001277251                                                           16    7355
NP_005500                                                              16    7355
NP_001277250                                                           16    7355
NP_005245                                                              16    7355
NP_057738                                                              16    7355
XP_006720521                                                           16    7355
XP_006720520                                                           16    7355
XP_005254331                                                           16    7355
XP_005254330                                                           16    7355
XP_006720519                                                           16    7355
XP_006720518                                                           16    7355
XP_005254313                                                           16    7355
XP_005254312                                                           16    7355
XP_006717985                                                           16    7355
XP_006717984                                                           16    7355
XP_005271970                                                           16    7355
XP_005271969                                                           16    7355
XP_005271967                                                           16    7355
XP_005271966                                                           16    7355
NP_005871                                                              15    9605
NP_001036212                                                           15    9605
NP_001036194                                                           15    9605
NP_005239                                                              15    9605
NP_060024                                                              15    9605
XP_005247602                                                           15    9605
XP_006710515                                                           15    9605
>NP_001013433
          Length = 589

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VTRLQFNKN 9
           VT LQFNKN
Sbjct: 509 VTCLQFNKN 517
>NP_060785
          Length = 627

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VTRLQFNKN 9
           VT LQFNKN
Sbjct: 547 VTCLQFNKN 555
>NP_361014
          Length = 707

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VTRLQFNKN 9
           VT LQFNKN
Sbjct: 627 VTCLQFNKN 635
>NP_001171868
          Length = 505

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRLQFNKN 9
           +TRL F KN
Sbjct: 271 ITRLDFKKN 279
>NP_065960
          Length = 733

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRLQFNKN 9
           +TRL F KN
Sbjct: 271 ITRLDFKKN 279
>NP_001171866
          Length = 687

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRLQFNKN 9
           +TRL F KN
Sbjct: 271 ITRLDFKKN 279
>NP_001171867
          Length = 505

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRLQFNKN 9
           +TRL F KN
Sbjct: 271 ITRLDFKKN 279
>XP_006712716
          Length = 668

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRLQFNKN 9
           +TRL F KN
Sbjct: 199 ITRLDFKKN 207
>XP_005263777
          Length = 735

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRLQFNKN 9
           +TRL F KN
Sbjct: 274 ITRLDFKKN 282
>XP_005263776
          Length = 736

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRLQFNKN 9
           +TRL F KN
Sbjct: 274 ITRLDFKKN 282
>XP_006712715
          Length = 740

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRLQFNKN 9
           +TRL F KN
Sbjct: 271 ITRLDFKKN 279
>XP_006712714
          Length = 740

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTRLQFNKN 9
           +TRL F KN
Sbjct: 271 ITRLDFKKN 279
>NP_060903
          Length = 1321

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLQFNKN 9
           RLQFNK+
Sbjct: 575 RLQFNKH 581
>NP_001140160
          Length = 1321

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RLQFNKN 9
           RLQFNK+
Sbjct: 575 RLQFNKH 581
>NP_001171864
          Length = 784

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TRLQFNK 8
           +RLQFNK
Sbjct: 294 SRLQFNK 300
>NP_053586
          Length = 852

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TRLQFNK 8
           +RLQFNK
Sbjct: 294 SRLQFNK 300
>NP_053584
          Length = 844

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TRLQFNK 8
           +RLQFNK
Sbjct: 294 SRLQFNK 300
>NP_004874
          Length = 850

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TRLQFNK 8
           +RLQFNK
Sbjct: 294 SRLQFNK 300
>NP_053585
          Length = 858

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TRLQFNK 8
           +RLQFNK
Sbjct: 294 SRLQFNK 300
>NP_001036083
          Length = 570

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TRLQFNKN 9
           T LQFN N
Sbjct: 109 TNLQFNNN 116
>NP_005475
          Length = 583

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TRLQFNKN 9
           T LQFN N
Sbjct: 122 TNLQFNNN 129
>XP_005267304
          Length = 500

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TRLQFNKN 9
           T LQFN N
Sbjct: 122 TNLQFNNN 129
>XP_006714873
          Length = 422

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TRLQFNK 8
           +RLQFNK
Sbjct: 294 SRLQFNK 300
>XP_006714872
          Length = 629

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TRLQFNK 8
           +RLQFNK
Sbjct: 294 SRLQFNK 300
>XP_006714871
          Length = 647

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TRLQFNK 8
          +RLQFNK
Sbjct: 91 SRLQFNK 97
>NP_055661
          Length = 1159

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RLQFNKN 9
            +LQ+NKN
Sbjct: 1053 KLQYNKN 1059
>XP_005251177
          Length = 1011

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RLQFNKN 9
           +LQ+NKN
Sbjct: 905 KLQYNKN 911
>NP_919290
          Length = 909

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VTRLQFNKN 9
          ++ LQ+NKN
Sbjct: 64 LSSLQYNKN 72
>NP_055619
          Length = 967

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RLQFNKN 9
          +LQFN+N
Sbjct: 33 QLQFNRN 39
>XP_005257995
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LQFNKN 9
           +QFNKN
Sbjct: 769 IQFNKN 774
>XP_005257994
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LQFNKN 9
           +QFNKN
Sbjct: 769 IQFNKN 774
>XP_006721674
          Length = 825

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RLQFNKN 9
          +LQFN+N
Sbjct: 33 QLQFNRN 39
>XP_006721673
          Length = 967

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RLQFNKN 9
          +LQFN+N
Sbjct: 33 QLQFNRN 39
>XP_006721672
          Length = 967

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RLQFNKN 9
          +LQFN+N
Sbjct: 33 QLQFNRN 39
>XP_005256939
          Length = 967

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RLQFNKN 9
          +LQFN+N
Sbjct: 33 QLQFNRN 39
>XP_005256938
          Length = 967

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RLQFNKN 9
          +LQFN+N
Sbjct: 33 QLQFNRN 39
>XP_005249698
          Length = 1044

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTRLQFNKN 9
           VT+LQ+N +
Sbjct: 416 VTKLQYNSS 424
>NP_001129396
          Length = 1590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTRLQFNKN 9
           VT+LQ+N +
Sbjct: 962 VTKLQYNSS 970
>NP_001273
          Length = 937

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LQFNKN 9
           +QFNKN
Sbjct: 755 IQFNKN 760
>NP_001025177
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LQFNKN 9
           +QFNKN
Sbjct: 769 IQFNKN 774
>NP_068602
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LQFNKN 9
           L+FNKN
Sbjct: 619 LEFNKN 624
>NP_001157285
          Length = 230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LQFNKN 9
           L+FNKN
Sbjct: 165 LEFNKN 170
>NP_056078
          Length = 3036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    VTRLQFN 7
            VTRL FN
Sbjct: 2809 VTRLYFN 2815
>NP_001167587
          Length = 3037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    VTRLQFN 7
            VTRL FN
Sbjct: 2810 VTRLYFN 2816
>NP_001167588
          Length = 2400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    VTRLQFN 7
            VTRL FN
Sbjct: 2173 VTRLYFN 2179
>NP_001277251
          Length = 2854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VTRLQFN 7
            VTR++FN
Sbjct: 2617 VTRMRFN 2623
>NP_005500
          Length = 3027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VTRLQFN 7
            VTR++FN
Sbjct: 2790 VTRMRFN 2796
>NP_001277250
          Length = 3048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VTRLQFN 7
            VTR++FN
Sbjct: 2811 VTRMRFN 2817
>NP_005245
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTRLQFNK 8
           +TRLQ NK
Sbjct: 385 MTRLQTNK 392
>NP_057738
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTRLQFNK 8
           +TRLQ NK
Sbjct: 373 MTRLQTNK 380
>XP_006720521
          Length = 387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTRLQFNK 8
           +TRLQ NK
Sbjct: 377 MTRLQTNK 384
>XP_006720520
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTRLQFNK 8
           +TRLQ NK
Sbjct: 378 MTRLQTNK 385
>XP_005254331
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTRLQFNK 8
           +TRLQ NK
Sbjct: 385 MTRLQTNK 392
>XP_005254330
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTRLQFNK 8
           +TRLQ NK
Sbjct: 385 MTRLQTNK 392
>XP_006720519
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTRLQFNK 8
           +TRLQ NK
Sbjct: 389 MTRLQTNK 396
>XP_006720518
          Length = 400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTRLQFNK 8
           +TRLQ NK
Sbjct: 390 MTRLQTNK 397
>XP_005254313
          Length = 3057

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    VTRLQFN 7
            VTRL FN
Sbjct: 2830 VTRLYFN 2836
>XP_005254312
          Length = 3058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    VTRLQFN 7
            VTRL FN
Sbjct: 2831 VTRLYFN 2837
>XP_006717985
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LQFNKN 9
           L+FNKN
Sbjct: 203 LEFNKN 208
>XP_006717984
          Length = 277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LQFNKN 9
           L+FNKN
Sbjct: 212 LEFNKN 217
>XP_005271970
          Length = 2931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VTRLQFN 7
            VTR++FN
Sbjct: 2849 VTRMRFN 2855
>XP_005271969
          Length = 3020

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VTRLQFN 7
            VTR++FN
Sbjct: 2783 VTRMRFN 2789
>XP_005271967
          Length = 3065

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VTRLQFN 7
            VTR++FN
Sbjct: 2828 VTRMRFN 2834
>XP_005271966
          Length = 3086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VTRLQFN 7
            VTR++FN
Sbjct: 2849 VTRMRFN 2855
>NP_005871
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TRLQFNKN 9
           T+LQ +KN
Sbjct: 133 TKLQLSKN 140
>NP_001036212
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TRLQFN 7
           TR+QFN
Sbjct: 212 TRVQFN 217
>NP_001036194
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TRLQFN 7
           TR+QFN
Sbjct: 212 TRVQFN 217
>NP_005239
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TRLQFN 7
           TR+QFN
Sbjct: 212 TRVQFN 217
>NP_060024
          Length = 1801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TRLQFNK 8
           T+L FNK
Sbjct: 286 TKLDFNK 292
>XP_005247602
          Length = 1665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   TRLQFNK 8
           T+L FNK
Sbjct: 150 TKLDFNK 156
>XP_006710515
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TRLQFN 7
           TR+QFN
Sbjct: 212 TRVQFN 217
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.132    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 529,787
Number of extensions: 781
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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