Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1935
NP_671714                                                              18    1935
XP_006715890                                                           18    1935
XP_005250160                                                           18    1935
XP_005250159                                                           18    1935
NP_002842                                                              17    3301
XP_005250576                                                           17    3301
NP_114104                                                              17    4312
NP_078966                                                              16    5631
NP_689961                                                              16    5631
NP_001136221                                                           16    5631
XP_006715958                                                           16    5631
XP_006715957                                                           16    5631
NP_640337                                                              16    7355
NP_001121187                                                           16    7355
NP_055417                                                              16    7355
XP_006721701                                                           16    7355
XP_005255953                                                           16    7355
XP_006715402                                                           16    7355
NP_996776                                                              16    7355
NP_077719                                                              15    9605
NP_740754                                                              15    9605
NP_061336                                                              15    9605
NP_055591                                                              15    9605
NP_631940                                                              15    9605
NP_476511                                                              15    9605
NP_001128686                                                           15    9605
NP_001128685                                                           15    9605
NP_476510                                                              15    9605
NP_001273988                                                           15    9605
NP_055867                                                              15    9605
NP_036553                                                              15    9605
NP_065845                                                              15    9605
NP_631900                                                              15    9605
NP_777377                                                              15    9605
NP_000709                                                              15    9605
NP_001230741                                                           15    9605
NP_056535                                                              15    9605
XP_005259737                                                           15    9605
XP_006719777                                                           15    9605
XP_006719776                                                           15    9605
XP_006719775                                                           15    9605
XP_006719774                                                           15    9605
XP_006719773                                                           15    9605
XP_005254057                                                           15    9605
XP_006719772                                                           15    9605
XP_006719771                                                           15    9605
XP_006719770                                                           15    9605
XP_005254054                                                           15    9605
XP_006715736                                                           15    9605
XP_006715735                                                           15    9605
XP_005249722                                                           15    9605
XP_006715734                                                           15    9605
XP_006715733                                                           15    9605
XP_006710845                                                           15    9605
XP_005270959                                                           15    9605
XP_005270958                                                           15    9605
XP_006710730                                                           15    9605
>NP_005742
          Length = 3907

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSESTVLPS 9
            VSESTV PS
Sbjct: 1375 VSESTVPPS 1383
>NP_671714
          Length = 3899

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSESTVLPS 9
            VSESTV PS
Sbjct: 1375 VSESTVPPS 1383
>XP_006715890
          Length = 3860

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSESTVLPS 9
            VSESTV PS
Sbjct: 1375 VSESTVPPS 1383
>XP_005250160
          Length = 3939

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSESTVLPS 9
            VSESTV PS
Sbjct: 1375 VSESTVPPS 1383
>XP_005250159
          Length = 3952

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VSESTVLPS 9
            VSESTV PS
Sbjct: 1375 VSESTVPPS 1383
>NP_002842
          Length = 2315

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    SESTVLPS 9
            SESTV+P+
Sbjct: 1066 SESTVMPN 1073
>XP_005250576
          Length = 2308

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    SESTVLPS 9
            SESTV+P+
Sbjct: 1066 SESTVMPN 1073
>NP_114104
          Length = 490

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  VSESTVLP 8
          VSE+T+LP
Sbjct: 75 VSENTMLP 82
>NP_078966
          Length = 14507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SESTVLP 8
            S+STVLP
Sbjct: 7000 SQSTVLP 7006
>NP_689961
          Length = 862

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSESTVLPS 9
           V +ST++PS
Sbjct: 590 VCQSTIIPS 598
>NP_001136221
          Length = 1029

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSESTVLPS 9
           V +ST++PS
Sbjct: 757 VCQSTIIPS 765
>XP_006715958
          Length = 915

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSESTVLPS 9
           V +ST++PS
Sbjct: 643 VCQSTIIPS 651
>XP_006715957
          Length = 915

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VSESTVLPS 9
           V +ST++PS
Sbjct: 643 VCQSTIIPS 651
>NP_640337
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSESTVLP 8
           +SE TV+P
Sbjct: 699 ISEGTVVP 706
>NP_001121187
          Length = 1151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSESTVLP 8
           +SE TV+P
Sbjct: 699 ISEGTVVP 706
>NP_055417
          Length = 1358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSESTVLPS 9
           V  ST+LPS
Sbjct: 923 VLSSTILPS 931
>XP_006721701
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SESTVLPS 9
          SES++LP+
Sbjct: 21 SESSILPA 28
>XP_005255953
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  VSESTVLPS 9
          V  STVLPS
Sbjct: 5  VLPSTVLPS 13

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4 STVLPS 9
         STVLPS
Sbjct: 3 STVLPS 8
>XP_006715402
          Length = 1135

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VSESTVLP 8
           +SE TV+P
Sbjct: 699 ISEGTVVP 706
>NP_996776
          Length = 267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SESTVLPS 9
          +E+TV+PS
Sbjct: 3  AEATVIPS 10
>NP_077719
          Length = 2471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    STVLPS 9
            STVLPS
Sbjct: 2215 STVLPS 2220
>NP_740754
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSESTVLP 8
           V +STVLP
Sbjct: 209 VIDSTVLP 216
>NP_061336
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VSESTVLP 8
           V +STVLP
Sbjct: 209 VIDSTVLP 216
>NP_055591
          Length = 679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>NP_631940
          Length = 471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>NP_476511
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>NP_001128686
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>NP_001128685
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 310 VTETTVVP 317
>NP_476510
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>NP_001273988
          Length = 1572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSESTVLPS 9
           +SESTV  S
Sbjct: 727 ISESTVFSS 735
>NP_055867
          Length = 1606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSESTVLPS 9
           +SESTV  S
Sbjct: 727 ISESTVFSS 735
>NP_036553
          Length = 1914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSESTVLPS 9
            V+E+T +PS
Sbjct: 1848 VAETTTVPS 1856
>NP_065845
          Length = 1537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSESTVLPS 9
           + EST +PS
Sbjct: 878 IKESTEIPS 886
>NP_631900
          Length = 120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  STVLPS 9
          STVLPS
Sbjct: 37 STVLPS 42
>NP_777377
          Length = 123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  STVLPS 9
          STVLPS
Sbjct: 37 STVLPS 42
>NP_000709
          Length = 2339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSESTVLPS 9
            + E+TV+PS
Sbjct: 1088 LGEATVVPS 1096
>NP_001230741
          Length = 2237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VSESTVLPS 9
            + E+TV+PS
Sbjct: 1088 LGEATVVPS 1096
>NP_056535
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SESTVLPS 9
           +E+TVLP+
Sbjct: 265 AEATVLPA 272
>XP_005259737
          Length = 120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  STVLPS 9
          STVLPS
Sbjct: 37 STVLPS 42
>XP_006719777
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>XP_006719776
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>XP_006719775
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>XP_006719774
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>XP_006719773
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>XP_005254057
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 307 VTETTVVP 314
>XP_006719772
          Length = 709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>XP_006719771
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>XP_006719770
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 308 VTETTVVP 315
>XP_005254054
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VSESTVLP 8
           V+E+TV+P
Sbjct: 307 VTETTVVP 314
>XP_006715736
          Length = 1573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSESTVLPS 9
           +SESTV  S
Sbjct: 728 ISESTVFSS 736
>XP_006715735
          Length = 1606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSESTVLPS 9
           +SESTV  S
Sbjct: 727 ISESTVFSS 735
>XP_005249722
          Length = 1607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSESTVLPS 9
           +SESTV  S
Sbjct: 728 ISESTVFSS 736
>XP_006715734
          Length = 1607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSESTVLPS 9
           +SESTV  S
Sbjct: 728 ISESTVFSS 736
>XP_006715733
          Length = 1608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VSESTVLPS 9
           +SESTV  S
Sbjct: 729 ISESTVFSS 737
>XP_006710845
          Length = 1492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VSESTVLPS 9
           + EST +PS
Sbjct: 833 IKESTEIPS 841
>XP_005270959
          Length = 2432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    STVLPS 9
            STVLPS
Sbjct: 2176 STVLPS 2181
>XP_005270958
          Length = 2432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    STVLPS 9
            STVLPS
Sbjct: 2176 STVLPS 2181
>XP_006710730
          Length = 2432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    STVLPS 9
            STVLPS
Sbjct: 2176 STVLPS 2181
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.291    0.108    0.255 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 487,493
Number of extensions: 633
Number of successful extensions: 59
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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