Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              20     299
NP_001263689                                                           20     299
NP_001119584                                                           20     299
NP_001119586                                                           20     299
NP_001263625                                                           20     299
NP_001119590                                                           20     299
NP_001263690                                                           20     299
NP_001119585                                                           20     299
NP_001263624                                                           20     299
NP_001119588                                                           20     299
NP_001119587                                                           20     299
NP_001119589                                                           20     299
NP_001263627                                                           20     299
NP_001263628                                                           20     299
NP_001263626                                                           20     299
NP_002903                                                              17    2528
NP_001273361                                                           17    2528
NP_001273360                                                           17    2528
NP_009089                                                              17    2528
NP_001007554                                                           17    2528
NP_001229820                                                           17    2528
NP_001123995                                                           17    2528
NP_001229822                                                           17    2528
NP_001229821                                                           17    2528
XP_005267148                                                           17    2528
XP_005267147                                                           17    2528
XP_006715607                                                           17    2528
XP_006715606                                                           17    2528
NP_620154                                                              17    4312
NP_001069                                                              16    5631
NP_001186763                                                           16    5631
NP_542413                                                              16    5631
NP_859078                                                              16    5631
NP_061092                                                              16    7355
XP_005254211                                                           16    7355
XP_005254210                                                           16    7355
XP_006720446                                                           16    7355
XP_005254209                                                           16    7355
XP_005254208                                                           16    7355
XP_005247644                                                           16    7355
XP_005247643                                                           16    7355
XP_005247641                                                           16    7355
XP_005247640                                                           16    7355
XP_005247639                                                           16    7355
NP_003983                                                              16    7355
NP_001123500                                                           16    7355
NP_006185                                                              15    9605
NP_055786                                                              15    9605
NP_005214                                                              15    9605
NP_778253                                                              15    9605
NP_001238774                                                           15    9605
NP_004873                                                              15    9605
NP_065881                                                              15    9605
NP_003295                                                              15    9605
XP_006720917                                                           15    9605
XP_005255206                                                           15    9605
XP_005255205                                                           15    9605
XP_006720916                                                           15    9605
XP_006720915                                                           15    9605
XP_006720218                                                           15    9605
XP_005247797                                                           15    9605
NP_055632                                                              15    9605
>NP_000537
          Length = 393

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 263 NLLGRNSF 270
>NP_001263689
          Length = 354

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 224 NLLGRNSF 231
>NP_001119584
          Length = 393

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 263 NLLGRNSF 270
>NP_001119586
          Length = 341

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 263 NLLGRNSF 270
>NP_001263625
          Length = 302

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 224 NLLGRNSF 231
>NP_001119590
          Length = 354

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 224 NLLGRNSF 231
>NP_001263690
          Length = 354

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 224 NLLGRNSF 231
>NP_001119585
          Length = 346

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 263 NLLGRNSF 270
>NP_001263624
          Length = 307

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 224 NLLGRNSF 231
>NP_001119588
          Length = 209

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 131 NLLGRNSF 138
>NP_001119587
          Length = 261

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 131 NLLGRNSF 138
>NP_001119589
          Length = 214

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 131 NLLGRNSF 138
>NP_001263627
          Length = 182

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 104 NLLGRNSF 111
>NP_001263628
          Length = 187

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 104 NLLGRNSF 111
>NP_001263626
          Length = 234

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NLLGRNSF 9
           NLLGRNSF
Sbjct: 104 NLLGRNSF 111
>NP_002903
          Length = 3130

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLLGRNSF 9
           N LG+NSF
Sbjct: 700 NTLGKNSF 707
>NP_001273361
          Length = 3052

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLLGRNSF 9
           N LG+NSF
Sbjct: 622 NTLGKNSF 629
>NP_001273360
          Length = 3052

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLLGRNSF 9
           N LG+NSF
Sbjct: 622 NTLGKNSF 629
>NP_009089
          Length = 767

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VNLLGRNS 8
           V LLGRNS
Sbjct: 476 VRLLGRNS 483
>NP_001007554
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VNLLGRNS 8
           V LLGRNS
Sbjct: 507 VRLLGRNS 514
>NP_001229820
          Length = 844

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VNLLGRNS 8
           V LLGRNS
Sbjct: 553 VRLLGRNS 560
>NP_001123995
          Length = 813

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VNLLGRNS 8
           V LLGRNS
Sbjct: 522 VRLLGRNS 529
>NP_001229822
          Length = 767

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VNLLGRNS 8
           V LLGRNS
Sbjct: 476 VRLLGRNS 483
>NP_001229821
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VNLLGRNS 8
           V LLGRNS
Sbjct: 507 VRLLGRNS 514
>XP_005267148
          Length = 2679

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLLGRNSF 9
           N LG+NSF
Sbjct: 700 NTLGKNSF 707
>XP_005267147
          Length = 2689

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLLGRNSF 9
           N LG+NSF
Sbjct: 700 NTLGKNSF 707
>XP_006715607
          Length = 3052

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLLGRNSF 9
           N LG+NSF
Sbjct: 622 NTLGKNSF 629
>XP_006715606
          Length = 3130

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLLGRNSF 9
           N LG+NSF
Sbjct: 700 NTLGKNSF 707
>NP_620154
          Length = 520

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NLLGRNSF 9
           N LG+NSF
Sbjct: 491 NSLGQNSF 498
>NP_001069
          Length = 739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VNLLGRN 7
           VNL+G+N
Sbjct: 294 VNLIGKN 300
>NP_001186763
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VNLLGRN 7
           VNL+G+N
Sbjct: 232 VNLIGKN 238
>NP_542413
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VNLLGRN 7
           VNL+G+N
Sbjct: 294 VNLIGKN 300
>NP_859078
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VNLLGRNS 8
           +NLLGR S
Sbjct: 99  INLLGRPS 106
>NP_061092
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VNLLGRNSF 9
           VN+LG+  F
Sbjct: 237 VNILGQEQF 245
>XP_005254211
          Length = 269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LLGRNSF 9
          LLG+N+F
Sbjct: 17 LLGKNTF 23
>XP_005254210
          Length = 490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLGRNSF 9
           LLG+N+F
Sbjct: 238 LLGKNTF 244
>XP_006720446
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLGRNSF 9
           LLG+N+F
Sbjct: 252 LLGKNTF 258
>XP_005254209
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLGRNSF 9
           LLG+N+F
Sbjct: 252 LLGKNTF 258
>XP_005254208
          Length = 652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLGRNSF 9
           LLG+N+F
Sbjct: 400 LLGKNTF 406
>XP_005247644
          Length = 188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VNLLGRNSF 9
          VN+LG+  F
Sbjct: 46 VNILGQEQF 54
>XP_005247643
          Length = 203

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VNLLGRNSF 9
          VN+LG+  F
Sbjct: 46 VNILGQEQF 54
>XP_005247641
          Length = 345

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VNLLGRNSF 9
           VN+LG+  F
Sbjct: 237 VNILGQEQF 245
>XP_005247640
          Length = 360

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VNLLGRNSF 9
           VN+LG+  F
Sbjct: 237 VNILGQEQF 245
>XP_005247639
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VNLLGRNSF 9
           VN+LG+  F
Sbjct: 237 VNILGQEQF 245
>NP_003983
          Length = 490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLGRNSF 9
           LLG+N+F
Sbjct: 238 LLGKNTF 244
>NP_001123500
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLGRNSF 9
           LLG+N+F
Sbjct: 386 LLGKNTF 392
>NP_006185
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LGRNSF 9
           LGRN+F
Sbjct: 228 LGRNNF 233
>NP_055786
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VNLLGRNSF 9
           + +LG NSF
Sbjct: 114 LQILGTNSF 122
>NP_005214
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LGRNSF 9
          LGRNS+
Sbjct: 93 LGRNSY 98
>NP_778253
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  VNLLGRNS 8
          +NL+GR++
Sbjct: 72 INLMGRST 79
>NP_001238774
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VNLLGRNS 8
          V++LGRN+
Sbjct: 80 VDVLGRNA 87
>NP_004873
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NLLGRN 7
           N+LGRN
Sbjct: 184 NVLGRN 189
>NP_065881
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NLLGRNSF 9
           N+LGR+ F
Sbjct: 147 NMLGRHFF 154
>NP_003295
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VNLLGRNS 8
          V++LGRN+
Sbjct: 80 VDVLGRNA 87
>XP_006720917
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LGRNSF 9
          LGRNS+
Sbjct: 24 LGRNSY 29
>XP_005255206
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LGRNSF 9
          LGRNS+
Sbjct: 24 LGRNSY 29
>XP_005255205
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LGRNSF 9
          LGRNS+
Sbjct: 93 LGRNSY 98
>XP_006720916
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LGRNSF 9
          LGRNS+
Sbjct: 93 LGRNSY 98
>XP_006720915
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LGRNSF 9
          LGRNS+
Sbjct: 93 LGRNSY 98
>XP_006720218
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LGRNSF 9
           LGRN+F
Sbjct: 228 LGRNNF 233
>XP_005247797
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VNLLGRNS 8
          V++LGRN+
Sbjct: 80 VDVLGRNA 87
>NP_055632
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VNLLGRNSF 9
           +  LG+N+F
Sbjct: 191 IRFLGKNAF 199
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.145    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 564,804
Number of extensions: 1132
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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