Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              19     665
NP_444254                                                              19     665
NP_444253                                                              19     665
NP_444255                                                              19     665
NP_444260                                                              19     665
NP_444259                                                              19     665
XP_005247551                                                           19     665
XP_005247550                                                           19     665
XP_006713712                                                           19     665
XP_005247549                                                           19     665
NP_001192222                                                           17    3301
NP_001192223                                                           17    3301
NP_000712                                                              17    3301
XP_005256953                                                           17    3301
NP_004095                                                              16    5631
XP_005267583                                                           16    5631
XP_006720178                                                           16    5631
XP_005267582                                                           16    5631
XP_006720177                                                           16    5631
XP_005267580                                                           16    5631
XP_006720176                                                           16    5631
XP_005267579                                                           16    5631
NP_859530                                                              16    7355
NP_005877                                                              16    7355
NP_071358                                                              16    7355
XP_006721186                                                           16    7355
XP_005255829                                                           16    7355
XP_006721185                                                           16    7355
XP_006721184                                                           16    7355
XP_005247955                                                           16    7355
XP_005247954                                                           16    7355
XP_005247953                                                           16    7355
XP_005247950                                                           16    7355
XP_005247951                                                           16    7355
XP_005247949                                                           16    7355
XP_005247948                                                           16    7355
XP_005245164                                                           16    7355
NP_150279                                                              16    7355
NP_004183                                                              15    9605
NP_001166945                                                           15    9605
NP_001166944                                                           15    9605
NP_775871                                                              15    9605
XP_005274840                                                           15    9605
XP_005274491                                                           15    9605
XP_006723528                                                           15    9605
XP_006723527                                                           15    9605
NP_001004478                                                           15    9605
>NP_444256
          Length = 1794

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    MISGLSGR 9
            MISGLSGR
Sbjct: 1643 MISGLSGR 1650
>NP_444254
          Length = 1845

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    MISGLSGR 9
            MISGLSGR
Sbjct: 1694 MISGLSGR 1701
>NP_444253
          Length = 1914

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    MISGLSGR 9
            MISGLSGR
Sbjct: 1763 MISGLSGR 1770
>NP_444255
          Length = 1863

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    MISGLSGR 9
            MISGLSGR
Sbjct: 1712 MISGLSGR 1719
>NP_444260
          Length = 154

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  MISGLSGR 9
          MISGLSGR
Sbjct: 3  MISGLSGR 10
>NP_444259
          Length = 153

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  MISGLSGR 9
          MISGLSGR
Sbjct: 3  MISGLSGR 10
>XP_005247551
          Length = 1855

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    MISGLSGR 9
            MISGLSGR
Sbjct: 1704 MISGLSGR 1711
>XP_005247550
          Length = 1856

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    MISGLSGR 9
            MISGLSGR
Sbjct: 1705 MISGLSGR 1712
>XP_006713712
          Length = 1923

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    MISGLSGR 9
            MISGLSGR
Sbjct: 1773 MISGLSGR 1780
>XP_005247549
          Length = 1924

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    MISGLSGR 9
            MISGLSGR
Sbjct: 1773 MISGLSGR 1780
>NP_001192222
          Length = 2313

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ISGLSGR 9
            +SGLSGR
Sbjct: 1926 VSGLSGR 1932
>NP_001192223
          Length = 2251

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ISGLSGR 9
            +SGLSGR
Sbjct: 1907 VSGLSGR 1913
>NP_000712
          Length = 2270

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ISGLSGR 9
            +SGLSGR
Sbjct: 1926 VSGLSGR 1932
>XP_005256953
          Length = 1178

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ISGLSGR 9
           +SGLSGR
Sbjct: 920 VSGLSGR 926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGLSGR 9
           SGLSGR
Sbjct: 808 SGLSGR 813
>NP_004095
          Length = 2511

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  VMISGLSGR 9
          V+I+G+SG+
Sbjct: 4  VVIAGMSGK 12
>XP_005267583
          Length = 493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 460 LVSGFSGR 467
>XP_006720178
          Length = 493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 460 LVSGFSGR 467
>XP_005267582
          Length = 493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 460 LVSGFSGR 467
>XP_006720177
          Length = 514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 481 LVSGFSGR 488
>XP_005267580
          Length = 515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 482 LVSGFSGR 489
>XP_006720176
          Length = 515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 482 LVSGFSGR 489
>XP_005267579
          Length = 515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 482 LVSGFSGR 489
>NP_859530
          Length = 380

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGLSGR 9
           SGLSGR
Sbjct: 107 SGLSGR 112
>NP_005877
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGLSGR 9
           SGLSGR
Sbjct: 634 SGLSGR 639
>NP_071358
          Length = 380

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGLSGR 9
           SGLSGR
Sbjct: 107 SGLSGR 112
>XP_006721186
          Length = 658

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGLSGR 9
           SGLSGR
Sbjct: 637 SGLSGR 642
>XP_005255829
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGLSGR 9
           SGLSGR
Sbjct: 651 SGLSGR 656
>XP_006721185
          Length = 675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGLSGR 9
           SGLSGR
Sbjct: 654 SGLSGR 659
>XP_006721184
          Length = 675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGLSGR 9
           SGLSGR
Sbjct: 654 SGLSGR 659
>XP_005247955
          Length = 936

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISGLSGR 9
           +SG+SGR
Sbjct: 744 LSGISGR 750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 522 VVSGYSGR 529
>XP_005247954
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISGLSGR 9
           +SG+SGR
Sbjct: 832 LSGISGR 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 610 VVSGYSGR 617
>XP_005247953
          Length = 1114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISGLSGR 9
           +SG+SGR
Sbjct: 922 LSGISGR 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 700 VVSGYSGR 707
>XP_005247950
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISGLSGR 9
           +SG+SGR
Sbjct: 923 LSGISGR 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 701 VVSGYSGR 708
>XP_005247951
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISGLSGR 9
           +SG+SGR
Sbjct: 923 LSGISGR 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 701 VVSGYSGR 708
>XP_005247949
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISGLSGR 9
           +SG+SGR
Sbjct: 923 LSGISGR 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 701 VVSGYSGR 708
>XP_005247948
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISGLSGR 9
           +SG+SGR
Sbjct: 923 LSGISGR 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 701 VVSGYSGR 708
>XP_005245164
          Length = 380

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGLSGR 9
           SGLSGR
Sbjct: 107 SGLSGR 112
>NP_150279
          Length = 1114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISGLSGR 9
           +SG+SGR
Sbjct: 922 LSGISGR 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           ++SG SGR
Sbjct: 700 VVSGYSGR 707
>NP_004183
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           M+S LSGR
Sbjct: 110 MLSRLSGR 117
>NP_001166945
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           M+S LSGR
Sbjct: 94  MLSRLSGR 101
>NP_001166944
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MISGLSGR 9
          M+S LSGR
Sbjct: 52 MLSRLSGR 59
>NP_775871
          Length = 8384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ISGLSG 8
            ISGLSG
Sbjct: 5212 ISGLSG 5217
>XP_005274840
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           M+S LSGR
Sbjct: 110 MLSRLSGR 117
>XP_005274491
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   MISGLSGR 9
           M+S LSGR
Sbjct: 110 MLSRLSGR 117
>XP_006723528
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  MISGLSG 8
          ++SGLSG
Sbjct: 24 LLSGLSG 30
>XP_006723527
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  MISGLSG 8
          ++SGLSG
Sbjct: 24 LLSGLSG 30
>NP_001004478
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  MISGLSG 8
          M+SGL+G
Sbjct: 81 MLSGLAG 87
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.141    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 496,078
Number of extensions: 813
Number of successful extensions: 56
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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