Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001119580                                                           16    5631
NP_000330                                                              16    5631
NP_001119579                                                           16    5631
NP_001660                                                              16    5631
XP_005274573                                                           16    5631
XP_005274572                                                           16    5631
XP_005274571                                                           16    5631
XP_005256176                                                           16    5631
NP_004254                                                              16    7355
NP_003310                                                              16    7355
NP_597676                                                              16    7355
NP_001258591                                                           16    7355
NP_001243779                                                           16    7355
NP_620168                                                              16    7355
NP_596869                                                              16    7355
NP_006086                                                              16    7355
NP_001098999                                                           16    7355
NP_001171473                                                           16    7355
XP_006722719                                                           16    7355
XP_006722718                                                           16    7355
XP_006722717                                                           16    7355
XP_006714052                                                           16    7355
XP_005248100                                                           16    7355
XP_005246888                                                           16    7355
XP_006712788                                                           16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
XP_006711982                                                           16    7355
NP_001254479                                                           16    7355
NP_597681                                                              16    7355
>NP_001119580
          Length = 1021

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VITLAVGR 8
           VITL +GR
Sbjct: 974 VITLPIGR 981
>NP_000330
          Length = 1030

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VITLAVGR 8
           VITL +GR
Sbjct: 983 VITLPIGR 990
>NP_001119579
          Length = 1029

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VITLAVGR 8
           VITL +GR
Sbjct: 982 VITLPIGR 989
>NP_001660
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VITLAVGRT 9
           ++TLA G+T
Sbjct: 211 ILTLAAGQT 219
>XP_005274573
          Length = 382

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VITLAVGRT 9
           ++TLA G+T
Sbjct: 211 ILTLAAGQT 219
>XP_005274572
          Length = 475

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VITLAVGRT 9
           ++TLA G+T
Sbjct: 211 ILTLAAGQT 219
>XP_005274571
          Length = 548

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VITLAVGRT 9
           ++TLA G+T
Sbjct: 211 ILTLAAGQT 219
>XP_005256176
          Length = 1020

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VITLAVGR 8
           VITL +GR
Sbjct: 973 VITLPIGR 980
>NP_004254
          Length = 770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VITLAVGR 8
           +IT AVGR
Sbjct: 201 IITRAVGR 208
>NP_003310
          Length = 26926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VITLAVGRT 9
             VIT+ VG+T
Sbjct: 11420 VITVRVGQT 11428
>NP_597676
          Length = 27051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VITLAVGRT 9
             VIT+ VG+T
Sbjct: 11545 VITVRVGQT 11553
>NP_001258591
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VITLAVGR 8
           +IT AVGR
Sbjct: 168 IITRAVGR 175
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VITLAVGRT 9
             VIT+ VG+T
Sbjct: 18844 VITVRVGQT 18852
>NP_620168
          Length = 1300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VITLAVG 7
           V+TLA+G
Sbjct: 932 VVTLAIG 938
>NP_596869
          Length = 33423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VITLAVGRT 9
             VIT+ VG+T
Sbjct: 17917 VITVRVGQT 17925
>NP_006086
          Length = 1164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VITLAVG 7
           V+TLA+G
Sbjct: 794 VVTLAIG 800
>NP_001098999
          Length = 1149

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VITLAVG 7
           V+TLA+G
Sbjct: 779 VVTLAIG 785
>NP_001171473
          Length = 1263

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VITLAVG 7
           V+TLA+G
Sbjct: 895 VVTLAIG 901
>XP_006722719
          Length = 1224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VITLAVG 7
           V+TLA+G
Sbjct: 856 VVTLAIG 862
>XP_006722718
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VITLAVG 7
           V+TLA+G
Sbjct: 942 VVTLAIG 948
>XP_006722717
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VITLAVG 7
           V+TLA+G
Sbjct: 942 VVTLAIG 948
>XP_006714052
          Length = 1000

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VITLAVG 7
           V+TLA+G
Sbjct: 630 VVTLAIG 636
>XP_005248100
          Length = 1164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VITLAVG 7
           V+TLA+G
Sbjct: 794 VVTLAIG 800
>XP_005246888
          Length = 22663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VITLAVGRT 9
            VIT+ VG+T
Sbjct: 7157 VITVRVGQT 7165
>XP_006712788
          Length = 24022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VITLAVGRT 9
            VIT+ VG+T
Sbjct: 8516 VITVRVGQT 8524
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VITLAVGRT 9
             VIT+ VG+T
Sbjct: 18472 VITVRVGQT 18480
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VITLAVGRT 9
             VIT+ VG+T
Sbjct: 19978 VITVRVGQT 19986
>XP_006711982
          Length = 700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VITLAVGR 8
           +IT AVGR
Sbjct: 201 IITRAVGR 208
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VITLAVGRT 9
             VIT+ VG+T
Sbjct: 20485 VITVRVGQT 20493
>NP_597681
          Length = 27118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     VITLAVGRT 9
             VIT+ VG+T
Sbjct: 11612 VITVRVGQT 11620
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.141    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 371,735
Number of extensions: 541
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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