Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           19     665
NP_000170                                                              19     665
NP_001268422                                                           19     665
NP_001268423                                                           19     665
XP_005264328                                                           19     665
NP_001165402                                                           18    1482
NP_001165401                                                           18    1482
NP_443068                                                              18    1482
NP_071407                                                              18    1482
NP_001165403                                                           18    1482
XP_006718005                                                           18    1482
XP_006718004                                                           18    1482
XP_006718003                                                           18    1482
XP_005275746                                                           18    1482
XP_003403671                                                           18    1482
XP_006710003                                                           18    1482
NP_001367                                                              17    3301
NP_071397                                                              17    3301
XP_006722869                                                           17    3301
XP_005272548                                                           17    3301
XP_006710877                                                           17    3301
XP_005244829                                                           17    3301
NP_065953                                                              17    3301
NP_001073898                                                           17    3301
NP_006609                                                              17    4312
NP_112219                                                              17    4312
XP_006722979                                                           17    4312
XP_006722784                                                           17    4312
XP_006722783                                                           17    4312
NP_002850                                                              16    5631
NP_001230685                                                           16    5631
NP_001074324                                                           16    5631
XP_005253973                                                           16    5631
XP_005253972                                                           16    5631
XP_005253971                                                           16    5631
XP_005253970                                                           16    5631
XP_006719602                                                           16    5631
XP_006719601                                                           16    5631
XP_006719600                                                           16    5631
XP_005253969                                                           16    5631
XP_005253967                                                           16    5631
XP_006719596                                                           16    5631
XP_006719595                                                           16    5631
XP_006719594                                                           16    5631
NP_001278253                                                           16    7355
NP_002518                                                              16    7355
NP_001096124                                                           16    7355
NP_001138826                                                           16    7355
NP_001138341                                                           16    7355
NP_006617                                                              16    7355
NP_037387                                                              16    7355
XP_006722053                                                           16    7355
XP_006722052                                                           16    7355
XP_005250413                                                           16    7355
XP_006716056                                                           16    7355
XP_005250412                                                           16    7355
XP_006716055                                                           16    7355
NP_005216                                                              15    9605
NP_055178                                                              15    9605
NP_001264984                                                           15    9605
NP_055504                                                              15    9605
NP_001277192                                                           15    9605
NP_065392                                                              15    9605
XP_005260820                                                           15    9605
XP_005266395                                                           15    9605
XP_006712684                                                           15    9605
XP_006712683                                                           15    9605
XP_006712682                                                           15    9605
XP_006712681                                                           15    9605
XP_005246730                                                           15    9605
XP_005246729                                                           15    9605
XP_006712680                                                           15    9605
XP_006712679                                                           15    9605
>NP_001268421
          Length = 1230

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VILLSEDTP 9
           VILL EDTP
Sbjct: 948 VILLPEDTP 956
>NP_000170
          Length = 1360

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VILLSEDTP 9
            VILL EDTP
Sbjct: 1078 VILLPEDTP 1086
>NP_001268422
          Length = 1058

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VILLSEDTP 9
           VILL EDTP
Sbjct: 776 VILLPEDTP 784
>NP_001268423
          Length = 1058

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VILLSEDTP 9
           VILL EDTP
Sbjct: 776 VILLPEDTP 784
>XP_005264328
          Length = 1261

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VILLSEDTP 9
           VILL EDTP
Sbjct: 979 VILLPEDTP 987
>NP_001165402
          Length = 1061

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 40 LLISEDTP 47
>NP_001165401
          Length = 1381

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 40 LLISEDTP 47
>NP_443068
          Length = 530

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 40 LLISEDTP 47
>NP_071407
          Length = 3354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 40 LLISEDTP 47
>NP_001165403
          Length = 406

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 40 LLISEDTP 47
>XP_006718005
          Length = 3397

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 85 LLISEDTP 92
>XP_006718004
          Length = 3399

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 85 LLISEDTP 92
>XP_006718003
          Length = 3419

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 85 LLISEDTP 92
>XP_005275746
          Length = 3352

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 40 LLISEDTP 47
>XP_003403671
          Length = 3354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 40 LLISEDTP 47
>XP_006710003
          Length = 3374

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ILLSEDTP 9
          +L+SEDTP
Sbjct: 40 LLISEDTP 47
>NP_001367
          Length = 4646

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VILLSEDTP 9
           V+ LSED+P
Sbjct: 137 VLTLSEDSP 145
>NP_071397
          Length = 1276

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VILLSEDTP 9
            ++ LSEDTP
Sbjct: 1237 MLSLSEDTP 1245
>XP_006722869
          Length = 1260

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ILLSEDTP 9
           ILL+E+TP
Sbjct: 837 ILLAEETP 844
>XP_005272548
          Length = 1265

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ILLSEDTP 9
           ILL+E+TP
Sbjct: 842 ILLAEETP 849
>XP_006710877
          Length = 1276

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VILLSEDTP 9
            ++ LSEDTP
Sbjct: 1237 MLSLSEDTP 1245
>XP_005244829
          Length = 1277

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VILLSEDTP 9
            ++ LSEDTP
Sbjct: 1238 MLSLSEDTP 1246
>NP_065953
          Length = 1249

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ILLSEDTP 9
           ILL+E+TP
Sbjct: 826 ILLAEETP 833
>NP_001073898
          Length = 1276

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ILLSEDTP 9
           ILL+E+TP
Sbjct: 853 ILLAEETP 860
>NP_006609
          Length = 1544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLSEDTP 9
           LLSE+TP
Sbjct: 879 LLSEETP 885
>NP_112219
          Length = 1103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VILLSEDTP 9
           +ILL+ED P
Sbjct: 291 LILLTEDQP 299
>XP_006722979
          Length = 1103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VILLSEDTP 9
           +ILL+ED P
Sbjct: 291 LILLTEDQP 299
>XP_006722784
          Length = 442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VILLSEDTP 9
           V LLS DTP
Sbjct: 426 VWLLSSDTP 434
>XP_006722783
          Length = 443

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VILLSEDTP 9
           V LLS DTP
Sbjct: 426 VWLLSSDTP 434
>NP_002850
          Length = 557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 23 VFLSEETP 30
>NP_001230685
          Length = 605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 23 VFLSEETP 30
>NP_001074324
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 23 VFLSEETP 30
>XP_005253973
          Length = 563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 29 VFLSEETP 36
>XP_005253972
          Length = 589

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 21 VFLSEETP 28
>XP_005253971
          Length = 597

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 29 VFLSEETP 36
>XP_005253970
          Length = 611

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 29 VFLSEETP 36
>XP_006719602
          Length = 645

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 29 VFLSEETP 36
>XP_006719601
          Length = 748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 29 VFLSEETP 36
>XP_006719600
          Length = 940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 29 VFLSEETP 36
>XP_005253969
          Length = 961

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 29 VFLSEETP 36
>XP_005253967
          Length = 1087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 29 VFLSEETP 36
>XP_006719596
          Length = 1127

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 21 VFLSEETP 28
>XP_006719595
          Length = 1129

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 23 VFLSEETP 30
>XP_006719594
          Length = 1135

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ILLSEDTP 9
          + LSE+TP
Sbjct: 29 VFLSEETP 36
>NP_001278253
          Length = 2639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VILLSEDTP 9
           VIL SE TP
Sbjct: 875 VILPSEPTP 883
>NP_002518
          Length = 257

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLSEDTP 9
           +LLS+ TP
Sbjct: 104 VLLSDSTP 111
>NP_001096124
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLSEDTP 9
           +LLS+ TP
Sbjct: 117 VLLSDSTP 124
>NP_001138826
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILLSEDT 8
           +LLSEDT
Sbjct: 349 MLLSEDT 355
>NP_001138341
          Length = 231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLSEDTP 9
           L+SED+P
Sbjct: 224 LISEDSP 230
>NP_006617
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VILLSEDTP 9
           +I +SED+P
Sbjct: 163 IIEISEDSP 171
>NP_037387
          Length = 735

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILLSEDT 8
           +LLSEDT
Sbjct: 372 MLLSEDT 378
>XP_006722053
          Length = 2608

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VILLSEDTP 9
           VIL SE TP
Sbjct: 875 VILPSEPTP 883
>XP_006722052
          Length = 2631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VILLSEDTP 9
           VIL SE TP
Sbjct: 875 VILPSEPTP 883
>XP_005250413
          Length = 528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILLSEDT 8
           +LLSEDT
Sbjct: 165 MLLSEDT 171
>XP_006716056
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILLSEDT 8
           +LLSEDT
Sbjct: 372 MLLSEDT 378
>XP_005250412
          Length = 701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILLSEDT 8
           +LLSEDT
Sbjct: 372 MLLSEDT 378
>XP_006716055
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILLSEDT 8
           +LLSEDT
Sbjct: 372 MLLSEDT 378
>NP_005216
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLSEDT 8
           LLSEDT
Sbjct: 233 LLSEDT 238
>NP_055178
          Length = 4579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VILLSEDTP 9
            +IL+ ED P
Sbjct: 1419 IILVHEDIP 1427
>NP_001264984
          Length = 4432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VILLSEDTP 9
            +IL+ ED P
Sbjct: 1272 IILVHEDIP 1280
>NP_055504
          Length = 2186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LLSEDT 8
            LLSEDT
Sbjct: 1750 LLSEDT 1755
>NP_001277192
          Length = 2180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LLSEDT 8
            LLSEDT
Sbjct: 1744 LLSEDT 1749
>NP_065392
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLSEDTP 9
           +LLS +TP
Sbjct: 184 LLLSSETP 191
>XP_005260820
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLSEDTP 9
           +LLS +TP
Sbjct: 184 LLLSSETP 191
>XP_005266395
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VILLSEDTP 9
            +IL+ ED P
Sbjct: 1428 IILVHEDIP 1436
>XP_006712684
          Length = 2189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LLSEDT 8
            LLSEDT
Sbjct: 1744 LLSEDT 1749
>XP_006712683
          Length = 2195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LLSEDT 8
            LLSEDT
Sbjct: 1750 LLSEDT 1755
>XP_006712682
          Length = 2199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LLSEDT 8
            LLSEDT
Sbjct: 1754 LLSEDT 1759
>XP_006712681
          Length = 2199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LLSEDT 8
            LLSEDT
Sbjct: 1763 LLSEDT 1768
>XP_005246730
          Length = 2199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LLSEDT 8
            LLSEDT
Sbjct: 1763 LLSEDT 1768
>XP_005246729
          Length = 2201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LLSEDT 8
            LLSEDT
Sbjct: 1763 LLSEDT 1768
>XP_006712680
          Length = 2206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LLSEDT 8
            LLSEDT
Sbjct: 1763 LLSEDT 1768
>XP_006712679
          Length = 2208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LLSEDT 8
            LLSEDT
Sbjct: 1763 LLSEDT 1768
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.138    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 678,693
Number of extensions: 1064
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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