Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     665
NP_001035957                                                           19     665
XP_006721991                                                           19     665
XP_006721990                                                           19     665
XP_006721989                                                           19     665
XP_005258041                                                           19     665
XP_006721988                                                           19     665
XP_006721987                                                           19     665
XP_006721986                                                           19     665
XP_005258040                                                           19     665
XP_006721985                                                           19     665
NP_036597                                                              17    4312
NP_068761                                                              17    4312
NP_001275962                                                           17    4312
NP_001275961                                                           17    4312
NP_951008                                                              17    4312
NP_006206                                                              17    4312
NP_758424                                                              16    5631
NP_061142                                                              16    5631
NP_001182188                                                           16    5631
NP_001129391                                                           16    7355
NP_861450                                                              16    7355
NP_055797                                                              16    7355
NP_005679                                                              16    7355
XP_005267486                                                           16    7355
XP_006720145                                                           16    7355
XP_005267485                                                           16    7355
XP_005267483                                                           16    7355
XP_005267482                                                           16    7355
XP_005267481                                                           16    7355
XP_005267480                                                           16    7355
XP_005267479                                                           16    7355
XP_005267478                                                           16    7355
XP_005267477                                                           16    7355
XP_005266418                                                           16    7355
XP_005247116                                                           16    7355
XP_005247115                                                           16    7355
>NP_000258
          Length = 2818

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1384 VGSAMFLRF 1392
>NP_001035957
          Length = 2839

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1405 VGSAMFLRF 1413
>XP_006721991
          Length = 1632

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1415 VGSAMFLRF 1423
>XP_006721990
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1415 VGSAMFLRF 1423
>XP_006721989
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1415 VGSAMFLRF 1423
>XP_005258041
          Length = 2836

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1384 VGSAMFLRF 1392
>XP_006721988
          Length = 2846

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1394 VGSAMFLRF 1402
>XP_006721987
          Length = 2849

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1415 VGSAMFLRF 1423
>XP_006721986
          Length = 2854

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1402 VGSAMFLRF 1410
>XP_005258040
          Length = 2857

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1405 VGSAMFLRF 1413
>XP_006721985
          Length = 2867

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VGSAMFLTF 9
            VGSAMFL F
Sbjct: 1415 VGSAMFLRF 1423
>NP_036597
          Length = 1015

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GSAMFLTF 9
           GS+MFL F
Sbjct: 863 GSSMFLRF 870
>NP_068761
          Length = 1133

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VGSAMFLTF 9
           VGS MFL +
Sbjct: 848 VGSRMFLVY 856
>NP_001275962
          Length = 427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VGSAMFLT 8
           VGSA+FL+
Sbjct: 139 VGSALFLS 146
>NP_001275961
          Length = 464

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VGSAMFLT 8
           VGSA+FL+
Sbjct: 176 VGSALFLS 183
>NP_951008
          Length = 1086

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VGSAMFLTF 9
           VGS MFL +
Sbjct: 848 VGSRMFLVY 856
>NP_006206
          Length = 427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VGSAMFLT 8
           VGSA+FL+
Sbjct: 139 VGSALFLS 146
>NP_758424
          Length = 1642

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VGSAMFL 7
           VGS+MFL
Sbjct: 694 VGSSMFL 700
>NP_061142
          Length = 1642

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VGSAMFL 7
           VGS+MFL
Sbjct: 694 VGSSMFL 700
>NP_001182188
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GSAMFLTF 9
          GSA FL+F
Sbjct: 31 GSARFLSF 38
>NP_001129391
          Length = 463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VGSAMFLT 8
           +GSA FLT
Sbjct: 303 LGSASFLT 310
>NP_861450
          Length = 461

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VGSAMFLT 8
           +GSA FLT
Sbjct: 303 LGSASFLT 310
>NP_055797
          Length = 2341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VGSAMFLT 8
            +GSA+F+T
Sbjct: 1505 LGSAIFIT 1512
>NP_005679
          Length = 1437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VGSAMFLTF 9
           +GSA+F+ F
Sbjct: 321 LGSAVFILF 329
>XP_005267486
          Length = 1421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VGSAMFLT 8
           +GSA+F+T
Sbjct: 585 LGSAIFIT 592
>XP_006720145
          Length = 1423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VGSAMFLT 8
           +GSA+F+T
Sbjct: 587 LGSAIFIT 594
>XP_005267485
          Length = 1459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VGSAMFLT 8
           +GSA+F+T
Sbjct: 623 LGSAIFIT 630
>XP_005267483
          Length = 2230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VGSAMFLT 8
            +GSA+F+T
Sbjct: 1394 LGSAIFIT 1401
>XP_005267482
          Length = 2243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VGSAMFLT 8
            +GSA+F+T
Sbjct: 1407 LGSAIFIT 1414
>XP_005267481
          Length = 2293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VGSAMFLT 8
            +GSA+F+T
Sbjct: 1457 LGSAIFIT 1464
>XP_005267480
          Length = 2336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VGSAMFLT 8
            +GSA+F+T
Sbjct: 1500 LGSAIFIT 1507
>XP_005267479
          Length = 2344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VGSAMFLT 8
            +GSA+F+T
Sbjct: 1508 LGSAIFIT 1515
>XP_005267478
          Length = 2348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VGSAMFLT 8
            +GSA+F+T
Sbjct: 1512 LGSAIFIT 1519
>XP_005267477
          Length = 2349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VGSAMFLT 8
            +GSA+F+T
Sbjct: 1513 LGSAIFIT 1520
>XP_005266418
          Length = 463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VGSAMFLT 8
           +GSA FLT
Sbjct: 303 LGSASFLT 310
>XP_005247116
          Length = 1437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VGSAMFLTF 9
           +GSA+F+ F
Sbjct: 321 LGSAVFILF 329
>XP_005247115
          Length = 1437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VGSAMFLTF 9
           +GSA+F+ F
Sbjct: 321 LGSAVFILF 329
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.145    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 330,413
Number of extensions: 605
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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