Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              19     665
NP_001186804                                                           17    4312
XP_005245596                                                           17    4312
NP_003559                                                              17    4312
NP_940857                                                              17    4312
NP_001269727                                                           16    5631
NP_001269729                                                           16    5631
NP_001269728                                                           16    5631
NP_056176                                                              16    5631
NP_059984                                                              16    5631
NP_060212                                                              16    5631
XP_006724893                                                           16    5631
XP_005274763                                                           16    5631
XP_006724892                                                           16    5631
XP_005274762                                                           16    5631
XP_006722557                                                           16    5631
XP_006722556                                                           16    5631
XP_005263689                                                           16    5631
XP_005263688                                                           16    5631
XP_006712454                                                           16    5631
XP_005263686                                                           16    5631
XP_005263685                                                           16    5631
XP_005263684                                                           16    5631
XP_005263683                                                           16    5631
XP_005263681                                                           16    5631
XP_005263680                                                           16    5631
XP_006712453                                                           16    5631
XP_005263679                                                           16    5631
XP_006712452                                                           16    5631
NP_001139669                                                           16    5631
NP_004817                                                              16    7355
NP_001277716                                                           16    7355
NP_001254                                                              16    7355
NP_001123367                                                           16    7355
XP_005262744                                                           16    7355
XP_005263976                                                           16    7355
NP_006579                                                              16    7355
NP_004371                                                              15    9605
NP_001073315                                                           15    9605
NP_001068567                                                           15    9605
NP_003717                                                              15    9605
NP_002198                                                              15    9605
NP_940918                                                              15    9605
NP_066923                                                              15    9605
NP_001185918                                                           15    9605
NP_874358                                                              15    9605
NP_060349                                                              15    9605
NP_001180473                                                           15    9605
NP_001146                                                              15    9605
XP_005259108                                                           15    9605
XP_005257813                                                           15    9605
XP_005257814                                                           15    9605
XP_005257812                                                           15    9605
XP_005255182                                                           15    9605
XP_006720911                                                           15    9605
XP_005255181                                                           15    9605
XP_006718287                                                           15    9605
XP_005268489                                                           15    9605
XP_006713200                                                           15    9605
NP_976248                                                              15    9605
>NP_115803
          Length = 1156

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VGIMQPTAQ 9
           VG MQPTAQ
Sbjct: 808 VGNMQPTAQ 816
>NP_001186804
          Length = 170

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VGIMQPTAQ 9
          VG+ QP A+
Sbjct: 40 VGVQQPNAE 48
>XP_005245596
          Length = 362

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VGIMQPTAQ 9
           + ++QPTAQ
Sbjct: 108 MALLQPTAQ 116
>NP_003559
          Length = 345

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VGIMQPTAQ 9
           + ++QPTAQ
Sbjct: 108 MALLQPTAQ 116
>NP_940857
          Length = 5147

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    GIMQPTAQ 9
            G+++PTA+
Sbjct: 1162 GVLEPTAE 1169
>NP_001269727
          Length = 1100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 699 VGVQQPQSQ 707
>NP_001269729
          Length = 1044

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 643 VGVQQPQSQ 651
>NP_001269728
          Length = 971

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 570 VGVQQPQSQ 578
>NP_056176
          Length = 1099

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 698 VGVQQPQSQ 706
>NP_059984
          Length = 1871

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VGIMQP 6
           VG+MQP
Sbjct: 696 VGVMQP 701
>NP_060212
          Length = 1178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VGIMQPTA 8
           VGI+ PTA
Sbjct: 770 VGILGPTA 777
>XP_006724893
          Length = 1719

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VGIMQP 6
           VG+MQP
Sbjct: 696 VGVMQP 701
>XP_005274763
          Length = 1789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VGIMQP 6
           VG+MQP
Sbjct: 614 VGVMQP 619
>XP_006724892
          Length = 1841

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VGIMQP 6
           VG+MQP
Sbjct: 696 VGVMQP 701
>XP_005274762
          Length = 1853

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VGIMQP 6
           VG+MQP
Sbjct: 696 VGVMQP 701
>XP_006722557
          Length = 1076

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VGIMQPTA 8
           VGI+ PTA
Sbjct: 668 VGILGPTA 675
>XP_006722556
          Length = 1100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VGIMQPTA 8
           VGI+ PTA
Sbjct: 692 VGILGPTA 699
>XP_005263689
          Length = 887

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 486 VGVQQPQSQ 494
>XP_005263688
          Length = 948

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 699 VGVQQPQSQ 707
>XP_006712454
          Length = 999

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 598 VGVQQPQSQ 606
>XP_005263686
          Length = 1014

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 613 VGVQQPQSQ 621
>XP_005263685
          Length = 1015

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 614 VGVQQPQSQ 622
>XP_005263684
          Length = 1037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 636 VGVQQPQSQ 644
>XP_005263683
          Length = 1038

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 637 VGVQQPQSQ 645
>XP_005263681
          Length = 1056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 655 VGVQQPQSQ 663
>XP_005263680
          Length = 1056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 655 VGVQQPQSQ 663
>XP_006712453
          Length = 1084

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 683 VGVQQPQSQ 691
>XP_005263679
          Length = 1086

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 685 VGVQQPQSQ 693
>XP_006712452
          Length = 1100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP +Q
Sbjct: 699 VGVQQPQSQ 707
>NP_001139669
          Length = 7081

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GIMQPTAQ 9
            G +QPTAQ
Sbjct: 5003 GPVQPTAQ 5010
>NP_004817
          Length = 775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GIMQPT 7
           GI+QPT
Sbjct: 586 GILQPT 591
>NP_001277716
          Length = 773

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GIMQPT 7
           GI+QPT
Sbjct: 584 GILQPT 589
>NP_001254
          Length = 461

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GIMQPT 7
           GI+QPT
Sbjct: 453 GILQPT 458
>NP_001123367
          Length = 171

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GIMQPTA 8
           G+M PTA
Sbjct: 126 GVMTPTA 132
>XP_005262744
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GIMQPT 7
           GI+QPT
Sbjct: 413 GILQPT 418
>XP_005263976
          Length = 227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  GIMQPT 7
          GI+QPT
Sbjct: 24 GILQPT 29
>NP_006579
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  GIMQPT 7
          GI+QPT
Sbjct: 24 GILQPT 29
>NP_004371
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP AQ
Sbjct: 808 VGMGQPPAQ 816
>NP_001073315
          Length = 2404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP AQ
Sbjct: 770 VGMGQPPAQ 778
>NP_001068567
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VGI +PT +
Sbjct: 256 VGIKEPTEE 264
>NP_003717
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VGI +PT +
Sbjct: 256 VGIKEPTEE 264
>NP_002198
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GIMQPTA 8
           GIM PT+
Sbjct: 775 GIMSPTS 781
>NP_940918
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VGIMQPT 7
           VGI+ PT
Sbjct: 516 VGILSPT 522
>NP_066923
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           +G+ QP A+
Sbjct: 209 IGVKQPIAE 217
>NP_001185918
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           +G+ QP A+
Sbjct: 158 IGVKQPIAE 166
>NP_874358
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VGIMQPT 7
           VGI++PT
Sbjct: 240 VGIVKPT 246
>NP_060349
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VGIMQPTA 8
           +GI+QP A
Sbjct: 184 LGILQPQA 191
>NP_001180473
          Length = 641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  VGIMQPTA 8
          VG+M+P A
Sbjct: 55 VGLMRPPA 62
>NP_001146
          Length = 673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  VGIMQPTA 8
          VG+M+P A
Sbjct: 87 VGLMRPPA 94
>XP_005259108
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VGIMQPTA 8
           +GI+QP A
Sbjct: 112 LGILQPQA 119
>XP_005257813
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VGI +PT +
Sbjct: 162 VGIKEPTEE 170
>XP_005257814
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VGI +PT +
Sbjct: 162 VGIKEPTEE 170
>XP_005257812
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VGI +PT +
Sbjct: 256 VGIKEPTEE 264
>XP_005255182
          Length = 2303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP AQ
Sbjct: 808 VGMGQPPAQ 816
>XP_006720911
          Length = 2355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP AQ
Sbjct: 808 VGMGQPPAQ 816
>XP_005255181
          Length = 2427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VGIMQPTAQ 9
           VG+ QP AQ
Sbjct: 793 VGMGQPPAQ 801
>XP_006718287
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VGIMQPT 7
           VGI+ PT
Sbjct: 454 VGILSPT 460
>XP_005268489
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  VGIMQPTA 8
          VG+M+P A
Sbjct: 87 VGLMRPPA 94
>XP_006713200
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GIMQPTAQ 9
          G +QPT+Q
Sbjct: 3  GPLQPTSQ 10
>NP_976248
          Length = 287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GIMQPTAQ 9
          G +QPT+Q
Sbjct: 32 GPLQPTSQ 39
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.129    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 723,400
Number of extensions: 992
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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