Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              18    1135
NP_001263689                                                           18    1135
NP_001119584                                                           18    1135
NP_001119586                                                           18    1135
NP_001263625                                                           18    1135
NP_001119590                                                           18    1135
NP_001263690                                                           18    1135
NP_001119585                                                           18    1135
NP_001263624                                                           18    1135
NP_001119588                                                           18    1135
NP_001119587                                                           18    1135
NP_001119589                                                           18    1135
NP_002832                                                              17    4312
NP_848599                                                              17    4312
XP_005265410                                                           17    4312
XP_005265409                                                           17    4312
XP_006713081                                                           17    4312
NP_001263627                                                           16    5631
NP_001263628                                                           16    5631
NP_001263626                                                           16    5631
NP_000470                                                              16    7355
NP_996611                                                              15    9605
NP_001120727                                                           15    9605
NP_631915                                                              15    9605
NP_055613                                                              15    9605
NP_001005169                                                           15    9605
NP_001005170                                                           15    9605
XP_006726255                                                           15    9605
XP_006726254                                                           15    9605
XP_006726253                                                           15    9605
XP_006726252                                                           15    9605
XP_006726215                                                           15    9605
XP_006726214                                                           15    9605
XP_006726213                                                           15    9605
XP_006726212                                                           15    9605
XP_006726371                                                           15    9605
XP_006726370                                                           15    9605
XP_006726117                                                           15    9605
XP_006726116                                                           15    9605
XP_006726115                                                           15    9605
XP_006726114                                                           15    9605
XP_006726018                                                           15    9605
XP_006726017                                                           15    9605
XP_006726016                                                           15    9605
XP_006726015                                                           15    9605
XP_006725930                                                           15    9605
XP_006725929                                                           15    9605
XP_006725928                                                           15    9605
XP_006725927                                                           15    9605
XP_006725829                                                           15    9605
XP_006725828                                                           15    9605
XP_006725827                                                           15    9605
XP_006725826                                                           15    9605
XP_006725703                                                           15    9605
XP_006725702                                                           15    9605
XP_006725701                                                           15    9605
XP_006725700                                                           15    9605
XP_006725699                                                           15    9605
XP_006725696                                                           15    9605
XP_006725695                                                           15    9605
XP_006726335                                                           15    9605
XP_006726334                                                           15    9605
XP_006726333                                                           15    9605
XP_006726332                                                           15    9605
XP_006725341                                                           15    9605
XP_006725340                                                           15    9605
XP_006723140                                                           15    9605
XP_006723139                                                           15    9605
XP_006723138                                                           15    9605
XP_006723137                                                           15    9605
XP_006722265                                                           15    9605
XP_006722264                                                           15    9605
NP_055448                                                              15    9605
>NP_000537
          Length = 393

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           V AMAIYKQ
Sbjct: 157 VRAMAIYKQ 165
>NP_001263689
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           V AMAIYKQ
Sbjct: 118 VRAMAIYKQ 126
>NP_001119584
          Length = 393

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           V AMAIYKQ
Sbjct: 157 VRAMAIYKQ 165
>NP_001119586
          Length = 341

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           V AMAIYKQ
Sbjct: 157 VRAMAIYKQ 165
>NP_001263625
          Length = 302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           V AMAIYKQ
Sbjct: 118 VRAMAIYKQ 126
>NP_001119590
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           V AMAIYKQ
Sbjct: 118 VRAMAIYKQ 126
>NP_001263690
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           V AMAIYKQ
Sbjct: 118 VRAMAIYKQ 126
>NP_001119585
          Length = 346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           V AMAIYKQ
Sbjct: 157 VRAMAIYKQ 165
>NP_001263624
          Length = 307

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           V AMAIYKQ
Sbjct: 118 VRAMAIYKQ 126
>NP_001119588
          Length = 209

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VGAMAIYKQ 9
          V AMAIYKQ
Sbjct: 25 VRAMAIYKQ 33
>NP_001119587
          Length = 261

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VGAMAIYKQ 9
          V AMAIYKQ
Sbjct: 25 VRAMAIYKQ 33
>NP_001119589
          Length = 214

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VGAMAIYKQ 9
          V AMAIYKQ
Sbjct: 25 VRAMAIYKQ 33
>NP_002832
          Length = 1445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           +GAMAI+ Q
Sbjct: 197 IGAMAIFFQ 205
>NP_848599
          Length = 3092

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GAMAIYKQ 9
            G M IYKQ
Sbjct: 2070 GTMEIYKQ 2077
>XP_005265410
          Length = 1416

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           +GAMAI+ Q
Sbjct: 197 IGAMAIFFQ 205
>XP_005265409
          Length = 1431

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VGAMAIYKQ 9
           +GAMAI+ Q
Sbjct: 183 IGAMAIFFQ 191
>XP_006713081
          Length = 3964

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GAMAIYKQ 9
            G M IYKQ
Sbjct: 2093 GTMEIYKQ 2100
>NP_001263627
          Length = 182

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4 MAIYKQ 9
         MAIYKQ
Sbjct: 1 MAIYKQ 6
>NP_001263628
          Length = 187

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4 MAIYKQ 9
         MAIYKQ
Sbjct: 1 MAIYKQ 6
>NP_001263626
          Length = 234

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4 MAIYKQ 9
         MAIYKQ
Sbjct: 1 MAIYKQ 6
>NP_000470
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VGAMAIYKQ 9
          VGA++ Y+Q
Sbjct: 73 VGALSAYEQ 81
>NP_996611
          Length = 980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>NP_001120727
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>NP_631915
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 777 GAMLLYK 783
>NP_055613
          Length = 1056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAMAIYKQ 9
           GAM I+K+
Sbjct: 545 GAMGIWKE 552
>NP_001005169
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VGAMAIY 7
           VG MA+Y
Sbjct: 249 VGVMALY 255
>NP_001005170
          Length = 350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VGAMAIY 7
           VG MA+Y
Sbjct: 275 VGVMALY 281
>XP_006726255
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006726254
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726253
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726252
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006726215
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006726214
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726213
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726212
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006726371
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726370
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726117
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006726116
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726115
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726114
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006726018
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006726017
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726016
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726015
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006725930
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006725929
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006725928
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006725927
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006725829
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006725828
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006725827
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006725826
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006725703
          Length = 980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006725702
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006725701
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006725700
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006725699
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006725696
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAMAIYKQ 9
           GAM I+K+
Sbjct: 415 GAMGIWKE 422
>XP_006725695
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAMAIYKQ 9
           GAM I+K+
Sbjct: 415 GAMGIWKE 422
>XP_006726335
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006726334
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726333
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006726332
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006725341
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAMAIYKQ 9
           GAM I+K+
Sbjct: 415 GAMGIWKE 422
>XP_006725340
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAMAIYKQ 9
           GAM I+K+
Sbjct: 415 GAMGIWKE 422
>XP_006723140
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006723139
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006723138
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 805 GAMLLYK 811
>XP_006723137
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GAMAIYK 8
           GAM +YK
Sbjct: 832 GAMLLYK 838
>XP_006722265
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAMAIYKQ 9
           GAM I+K+
Sbjct: 415 GAMGIWKE 422
>XP_006722264
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAMAIYKQ 9
           GAM I+K+
Sbjct: 415 GAMGIWKE 422
>NP_055448
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GAMAIYKQ 9
           GA+A YK+
Sbjct: 181 GALAYYKK 188
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.133    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 351,101
Number of extensions: 430
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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