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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1482
XP_006716142                                                           18    1482
XP_005250088                                                           18    1482
XP_006716141                                                           18    1482
XP_005250085                                                           18    1482
XP_006716140                                                           18    1482
XP_005250084                                                           18    1482
XP_005250083                                                           18    1482
XP_005250082                                                           18    1482
NP_758859                                                              16    5631
NP_071900                                                              16    5631
XP_005266019                                                           16    5631
XP_005266018                                                           16    5631
XP_005266017                                                           16    5631
XP_006714965                                                           16    5631
XP_006714964                                                           16    5631
XP_005266016                                                           16    5631
NP_002045                                                              16    7355
NP_579878                                                              16    7355
NP_579890                                                              16    7355
NP_579877                                                              16    7355
NP_001035889                                                           16    7355
NP_689775                                                              16    7355
NP_036345                                                              16    7355
XP_005273475                                                           16    7355
XP_006716359                                                           16    7355
XP_006716358                                                           16    7355
XP_006716357                                                           16    7355
XP_006713978                                                           16    7355
XP_005248059                                                           16    7355
XP_005248058                                                           16    7355
NP_001971                                                              15    9605
NP_919337                                                              15    9605
NP_002636                                                              15    9605
NP_004410                                                              15    9605
XP_006719339                                                           15    9605
XP_005253614                                                           15    9605
XP_005253613                                                           15    9605
XP_005253037                                                           15    9605
XP_005253036                                                           15    9605
XP_005253035                                                           15    9605
XP_005253034                                                           15    9605

>NP_733751
          Length = 4911

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           V TADISSN
Sbjct: 924 VSTADISSN 932



>XP_006716142
          Length = 4927

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           V TADISSN
Sbjct: 925 VSTADISSN 933



>XP_005250088
          Length = 4928

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           V TADISSN
Sbjct: 925 VSTADISSN 933



>XP_006716141
          Length = 4959

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           V TADISSN
Sbjct: 925 VSTADISSN 933



>XP_005250085
          Length = 4979

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           V TADISSN
Sbjct: 925 VSTADISSN 933



>XP_006716140
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           V TADISSN
Sbjct: 925 VSTADISSN 933



>XP_005250084
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           V TADISSN
Sbjct: 925 VSTADISSN 933



>XP_005250083
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           V TADISSN
Sbjct: 924 VSTADISSN 932



>XP_005250082
          Length = 4983

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           V TADISSN
Sbjct: 925 VSTADISSN 933



>NP_758859
          Length = 2427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            +FTAD+S
Sbjct: 1615 IFTADLS 1621



>NP_071900
          Length = 2696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            +FTAD+S
Sbjct: 1884 IFTADLS 1890



>XP_005266019
          Length = 1194

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VFTADIS 7
           +FTAD+S
Sbjct: 382 IFTADLS 388



>XP_005266018
          Length = 2427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            +FTAD+S
Sbjct: 1615 IFTADLS 1621



>XP_005266017
          Length = 2427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            +FTAD+S
Sbjct: 1615 IFTADLS 1621



>XP_006714965
          Length = 2427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            +FTAD+S
Sbjct: 1615 IFTADLS 1621



>XP_006714964
          Length = 2696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            +FTAD+S
Sbjct: 1884 IFTADLS 1890



>XP_005266016
          Length = 2696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            +FTAD+S
Sbjct: 1884 IFTADLS 1890



>NP_002045
          Length = 180

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   FTADISS 8
           FT+D+SS
Sbjct: 103 FTSDVSS 109



>NP_579878
          Length = 1365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            ++TADIS
Sbjct: 1005 IYTADIS 1011



>NP_579890
          Length = 1365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            ++TADIS
Sbjct: 1005 IYTADIS 1011



>NP_579877
          Length = 1365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            ++TADIS
Sbjct: 1005 IYTADIS 1011



>NP_001035889
          Length = 1365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            ++TADIS
Sbjct: 1005 IYTADIS 1011



>NP_689775
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FTADISSN 9
           FTA++SS+
Sbjct: 295 FTAEVSSD 302



>NP_036345
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TADISSN 9
           T DISSN
Sbjct: 258 TGDISSN 264



>XP_005273475
          Length = 635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FTADISSN 9
           FTA++SS+
Sbjct: 295 FTAEVSSD 302



>XP_006716359
          Length = 1028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FTADISSN 9
           FTA++SS+
Sbjct: 300 FTAEVSSD 307



>XP_006716358
          Length = 1028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FTADISSN 9
           FTA++SS+
Sbjct: 300 FTAEVSSD 307



>XP_006716357
          Length = 1028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FTADISSN 9
           FTA++SS+
Sbjct: 300 FTAEVSSD 307



>XP_006713978
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VFTADIS 7
           ++TADIS
Sbjct: 224 IYTADIS 230



>XP_005248059
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VFTADIS 7
           ++TADIS
Sbjct: 936 IYTADIS 942



>XP_005248058
          Length = 1365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFTADIS 7
            ++TADIS
Sbjct: 1005 IYTADIS 1011



>NP_001971
          Length = 287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           +FT+DI S+
Sbjct: 175 IFTSDIISD 183



>NP_919337
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           +FT+DI S+
Sbjct: 175 IFTSDIISD 183



>NP_002636
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTADISS 8
           FT D+SS
Sbjct: 439 FTCDVSS 445



>NP_004410
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TADISSN 9
           TADISS+
Sbjct: 235 TADISSH 241



>XP_006719339
          Length = 260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           +FT+DI S+
Sbjct: 147 IFTSDIISD 155



>XP_005253614
          Length = 277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           +FT+DI S+
Sbjct: 175 IFTSDIISD 183



>XP_005253613
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFTADISSN 9
           +FT+DI S+
Sbjct: 175 IFTSDIISD 183



>XP_005253037
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  FTADISS 8
          FT D+SS
Sbjct: 59 FTCDVSS 65



>XP_005253036
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTADISS 8
           FT D+SS
Sbjct: 439 FTCDVSS 445



>XP_005253035
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTADISS 8
           FT D+SS
Sbjct: 439 FTCDVSS 445



>XP_005253034
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FTADISS 8
           FT D+SS
Sbjct: 439 FTCDVSS 445



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.121    0.308 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 362,433
Number of extensions: 460
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)