Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              19     869
XP_006716142                                                           19     869
XP_005250088                                                           19     869
XP_006716141                                                           19     869
XP_005250085                                                           19     869
XP_006716140                                                           19     869
XP_005250084                                                           19     869
XP_005250083                                                           19     869
XP_005250082                                                           19     869
NP_056528                                                              16    5631
NP_001165949                                                           16    5631
NP_001165948                                                           16    5631
NP_001019831                                                           16    5631
NP_009049                                                              16    5631
NP_003938                                                              16    5631
NP_001398                                                              16    5631
NP_001007538                                                           16    5631
NP_848635                                                              16    5631
XP_006714558                                                           16    5631
XP_006713880                                                           16    5631
XP_006713879                                                           16    5631
XP_006713878                                                           16    5631
XP_006713877                                                           16    5631
XP_006713876                                                           16    5631
XP_006713875                                                           16    5631
XP_006713874                                                           16    5631
XP_006713873                                                           16    5631
NP_001159403                                                           16    7355
NP_001025                                                              16    7355
NP_002903                                                              16    7355
NP_001273361                                                           16    7355
NP_001273360                                                           16    7355
NP_115272                                                              16    7355
NP_061750                                                              16    7355
NP_849157                                                              16    7355
XP_005267148                                                           16    7355
XP_005267147                                                           16    7355
XP_006715607                                                           16    7355
XP_006715606                                                           16    7355
XP_006714159                                                           16    7355
XP_006714158                                                           16    7355
XP_006714157                                                           16    7355
NP_115269                                                              16    7355
NP_115267                                                              16    7355
NP_001005365                                                           16    7355
NP_061746                                                              16    7355
NP_003727                                                              16    7355
NP_076991                                                              15    9605
NP_775922                                                              15    9605
>NP_733751
          Length = 4911

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VFSQDVQVN 9
            VFSQ VQVN
Sbjct: 2982 VFSQGVQVN 2990
>XP_006716142
          Length = 4927

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VFSQDVQVN 9
            VFSQ VQVN
Sbjct: 2999 VFSQGVQVN 3007
>XP_005250088
          Length = 4928

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VFSQDVQVN 9
            VFSQ VQVN
Sbjct: 2999 VFSQGVQVN 3007
>XP_006716141
          Length = 4959

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VFSQDVQVN 9
            VFSQ VQVN
Sbjct: 2999 VFSQGVQVN 3007
>XP_005250085
          Length = 4979

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VFSQDVQVN 9
            VFSQ VQVN
Sbjct: 2999 VFSQGVQVN 3007
>XP_006716140
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VFSQDVQVN 9
            VFSQ VQVN
Sbjct: 2999 VFSQGVQVN 3007
>XP_005250084
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VFSQDVQVN 9
            VFSQ VQVN
Sbjct: 2999 VFSQGVQVN 3007
>XP_005250083
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VFSQDVQVN 9
            VFSQ VQVN
Sbjct: 2998 VFSQGVQVN 3006
>XP_005250082
          Length = 4983

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    VFSQDVQVN 9
            VFSQ VQVN
Sbjct: 2999 VFSQGVQVN 3007
>NP_056528
          Length = 351

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSQDVQV 8
           FSQ+VQV
Sbjct: 111 FSQEVQV 117
>NP_001165949
          Length = 299

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FSQDVQV 8
          FSQ+VQV
Sbjct: 59 FSQEVQV 65
>NP_001165948
          Length = 423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FSQDVQV 8
           FSQ+VQV
Sbjct: 183 FSQEVQV 189
>NP_001019831
          Length = 2986

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 540 VFQQDVQ 546
>NP_009049
          Length = 3097

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 570 VFQQDVQ 576
>NP_003938
          Length = 1663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 540 VFQQDVQ 546
>NP_001398
          Length = 3312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    FSQDVQV 8
            FSQDV+V
Sbjct: 2223 FSQDVRV 2229
>NP_001007538
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VFSQDVQVN 9
           VFS++VQV+
Sbjct: 257 VFSRNVQVS 265
>NP_848635
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VFSQDVQVN 9
           VFS++VQV+
Sbjct: 257 VFSRNVQVS 265
>XP_006714558
          Length = 2612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  VFSQDVQ 7
          VF QDVQ
Sbjct: 85 VFQQDVQ 91
>XP_006713880
          Length = 1530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 542 VFQQDVQ 548
>XP_006713879
          Length = 1656

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 542 VFQQDVQ 548
>XP_006713878
          Length = 1665

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 542 VFQQDVQ 548
>XP_006713877
          Length = 2956

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 542 VFQQDVQ 548
>XP_006713876
          Length = 2966

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 542 VFQQDVQ 548
>XP_006713875
          Length = 2975

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 542 VFQQDVQ 548
>XP_006713874
          Length = 2979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 542 VFQQDVQ 548
>XP_006713873
          Length = 2988

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VFSQDVQ 7
           VF QDVQ
Sbjct: 542 VFQQDVQ 548
>NP_001159403
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   FSQDVQV 8
           FSQ+VQ+
Sbjct: 209 FSQEVQI 215
>NP_001025
          Length = 389

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   FSQDVQV 8
           FSQ+VQ+
Sbjct: 149 FSQEVQI 155
>NP_002903
          Length = 3130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFSQDVQ 7
            VFSQD++
Sbjct: 2354 VFSQDIR 2360
>NP_001273361
          Length = 3052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFSQDVQ 7
            VFSQD++
Sbjct: 2276 VFSQDIR 2282
>NP_001273360
          Length = 3052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFSQDVQ 7
            VFSQD++
Sbjct: 2276 VFSQDIR 2282
>NP_115272
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VFSQDV 6
           VFSQDV
Sbjct: 241 VFSQDV 246
>NP_061750
          Length = 929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VFSQDV 6
           VFSQDV
Sbjct: 241 VFSQDV 246
>NP_849157
          Length = 1077

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VFSQDVQV 8
           +FSQD+ V
Sbjct: 564 LFSQDISV 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VFSQDVQV 8
           +FSQD+ V
Sbjct: 722 LFSQDISV 729
>XP_005267148
          Length = 2679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFSQDVQ 7
            VFSQD++
Sbjct: 2354 VFSQDIR 2360
>XP_005267147
          Length = 2689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFSQDVQ 7
            VFSQD++
Sbjct: 2354 VFSQDIR 2360
>XP_006715607
          Length = 3052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFSQDVQ 7
            VFSQD++
Sbjct: 2276 VFSQDIR 2282
>XP_006715606
          Length = 3130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    VFSQDVQ 7
            VFSQD++
Sbjct: 2354 VFSQDIR 2360
>XP_006714159
          Length = 1077

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VFSQDVQV 8
           +FSQD+ V
Sbjct: 564 LFSQDISV 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VFSQDVQV 8
           +FSQD+ V
Sbjct: 722 LFSQDISV 729
>XP_006714158
          Length = 1077

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VFSQDVQV 8
           +FSQD+ V
Sbjct: 564 LFSQDISV 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VFSQDVQV 8
           +FSQD+ V
Sbjct: 722 LFSQDISV 729
>XP_006714157
          Length = 1077

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VFSQDVQV 8
           +FSQD+ V
Sbjct: 564 LFSQDISV 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VFSQDVQV 8
           +FSQD+ V
Sbjct: 722 LFSQDISV 729
>NP_115269
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VFSQDV 6
           VFSQDV
Sbjct: 241 VFSQDV 246
>NP_115267
          Length = 811

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VFSQDV 6
           VFSQDV
Sbjct: 241 VFSQDV 246
>NP_001005365
          Length = 498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VFSQDV 6
           VFSQDV
Sbjct: 257 VFSQDV 262
>NP_061746
          Length = 931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VFSQDV 6
           VFSQDV
Sbjct: 241 VFSQDV 246
>NP_003727
          Length = 923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VFSQDV 6
           VFSQDV
Sbjct: 241 VFSQDV 246
>NP_076991
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  FSQDVQVN 9
          F Q VQ+N
Sbjct: 30 FKQHVQIN 37
>NP_775922
          Length = 6996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFSQDVQVN 9
           +FSQD+ V+
Sbjct: 866 MFSQDLSVD 874
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.130    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 482,987
Number of extensions: 580
Number of successful extensions: 53
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package