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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001276866                                                           20     509
NP_004439                                                              20     509
NP_001276865                                                           20     509
NP_001005862                                                           20     509
XP_005257197                                                           20     509
XP_006721828                                                           20     509
NP_000143                                                              17    3301
NP_001073271                                                           17    3301
NP_001073272                                                           17    3301
XP_005257251                                                           17    3301
XP_005257250                                                           17    3301
XP_006710508                                                           16    5631
XP_006710507                                                           16    5631
NP_689910                                                              16    5631
NP_000284                                                              16    7355
NP_001027005                                                           16    7355
NP_057291                                                              16    7355
XP_005256041                                                           16    7355
XP_005256040                                                           16    7355
XP_005246225                                                           16    7355
XP_005246224                                                           16    7355
NP_004203                                                              16    7355
NP_001137432                                                           15    9605
NP_001275988                                                           15    9605
NP_004790                                                              15    9605
NP_015563                                                              15    9605
NP_001275990                                                           15    9605
NP_001275987                                                           15    9605
NP_112168                                                              15    9605
NP_001137431                                                           15    9605
XP_006718343                                                           15    9605
XP_006718342                                                           15    9605
XP_006718341                                                           15    9605
XP_005264347                                                           15    9605
XP_005264346                                                           15    9605
XP_005264345                                                           15    9605
XP_005264344                                                           15    9605

>NP_001276866
          Length = 1055

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VFGILIKRQ 9
           VFGILIKR+
Sbjct: 670 VFGILIKRR 678



>NP_004439
          Length = 1255

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VFGILIKRQ 9
           VFGILIKR+
Sbjct: 670 VFGILIKRR 678



>NP_001276865
          Length = 1240

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VFGILIKRQ 9
           VFGILIKR+
Sbjct: 655 VFGILIKRR 663



>NP_001005862
          Length = 1225

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VFGILIKRQ 9
           VFGILIKR+
Sbjct: 640 VFGILIKRR 648



>XP_005257197
          Length = 1225

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VFGILIKRQ 9
           VFGILIKR+
Sbjct: 640 VFGILIKRR 648



>XP_006721828
          Length = 1336

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VFGILIKRQ 9
           VFGILIKR+
Sbjct: 751 VFGILIKRR 759



>NP_000143
          Length = 952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FGILIKRQ 9
           FG++++RQ
Sbjct: 218 FGVIVRRQ 225



>NP_001073271
          Length = 952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FGILIKRQ 9
           FG++++RQ
Sbjct: 218 FGVIVRRQ 225



>NP_001073272
          Length = 952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FGILIKRQ 9
           FG++++RQ
Sbjct: 218 FGVIVRRQ 225



>XP_005257251
          Length = 952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FGILIKRQ 9
           FG++++RQ
Sbjct: 218 FGVIVRRQ 225



>XP_005257250
          Length = 952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FGILIKRQ 9
           FG++++RQ
Sbjct: 218 FGVIVRRQ 225



>XP_006710508
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GILIKRQ 9
           GILIK+Q
Sbjct: 663 GILIKKQ 669



>XP_006710507
          Length = 719

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GILIKRQ 9
           GILIK+Q
Sbjct: 705 GILIKKQ 711



>NP_689910
          Length = 719

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GILIKRQ 9
           GILIK+Q
Sbjct: 705 GILIKKQ 711



>NP_000284
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFGILIKRQ 9
           + GIL+KR+
Sbjct: 743 LLGILLKRE 751



>NP_001027005
          Length = 1086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFGILIKRQ 9
           + GIL+KR+
Sbjct: 736 LLGILLKRE 744



>NP_057291
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VFGILIKR 8
           V GIL+KR
Sbjct: 481 VSGILVKR 488



>XP_005256041
          Length = 1086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFGILIKRQ 9
           + GIL+KR+
Sbjct: 736 LLGILLKRE 744



>XP_005256040
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VFGILIKRQ 9
           + GIL+KR+
Sbjct: 743 LLGILLKRE 751



>XP_005246225
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VFGILIKR 8
           V GIL+KR
Sbjct: 444 VSGILVKR 451



>XP_005246224
          Length = 674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VFGILIKR 8
           V GIL+KR
Sbjct: 471 VSGILVKR 478



>NP_004203
          Length = 658

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VFGILIKR 8
           VFGIL+ R
Sbjct: 211 VFGILVIR 218



>NP_001137432
          Length = 115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GILIKRQ 9
          GIL++RQ
Sbjct: 13 GILVQRQ 19



>NP_001275988
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  FGILIKRQ 9
          FG+ +K+Q
Sbjct: 79 FGLAVKKQ 86



>NP_004790
          Length = 1425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VFGILIKR 8
            +FGILI++
Sbjct: 1054 LFGILIQK 1061



>NP_015563
          Length = 1366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VFGILIKR 8
            +FGILI++
Sbjct: 995  LFGILIQK 1002



>NP_001275990
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FGILIKRQ 9
           FG+ +K+Q
Sbjct: 266 FGLAVKKQ 273



>NP_001275987
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FGILIKRQ 9
           FG+ +K+Q
Sbjct: 225 FGLAVKKQ 232



>NP_112168
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FGILIKRQ 9
           FG+ +K+Q
Sbjct: 266 FGLAVKKQ 273



>NP_001137431
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GILIKRQ 9
          GIL++RQ
Sbjct: 92 GILVQRQ 98



>XP_006718343
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FGILIKRQ 9
           FG+ +K+Q
Sbjct: 225 FGLAVKKQ 232



>XP_006718342
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FGILIKRQ 9
           FG+ +K+Q
Sbjct: 266 FGLAVKKQ 273



>XP_006718341
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FGILIKRQ 9
           FG+ +K+Q
Sbjct: 225 FGLAVKKQ 232



>XP_005264347
          Length = 115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GILIKRQ 9
          GIL++RQ
Sbjct: 13 GILVQRQ 19



>XP_005264346
          Length = 115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GILIKRQ 9
          GIL++RQ
Sbjct: 13 GILVQRQ 19



>XP_005264345
          Length = 115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GILIKRQ 9
          GIL++RQ
Sbjct: 13 GILVQRQ 19



>XP_005264344
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GILIKRQ 9
          GIL++RQ
Sbjct: 92 GILVQRQ 98



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.164    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 430,085
Number of extensions: 585
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)