Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245202                                                           18    1935
NP_001245200                                                           18    1935
NP_001161091                                                           18    1935
NP_000240                                                              18    1935
NP_001161090                                                           18    1935
NP_001161089                                                           18    1935
NP_001245203                                                           18    1935
XP_005265221                                                           18    1935
XP_005265220                                                           18    1935
NP_003740                                                              17    3301
NP_001013649                                                           17    4312
XP_006724707                                                           17    4312
NP_065753                                                              16    7355
NP_001008781                                                           16    7355
XP_006718827                                                           16    7355
XP_006716871                                                           16    7355
NP_001243888                                                           15    9605
NP_001277                                                              15    9605
>NP_001245202
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VESISLRKA 9
          VES SLRKA
Sbjct: 26 VESTSLRKA 34
>NP_001245200
          Length = 687

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VESISLRKA 9
           VES SLRKA
Sbjct: 267 VESTSLRKA 275
>NP_001161091
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VESISLRKA 9
          VES SLRKA
Sbjct: 26 VESTSLRKA 34
>NP_000240
          Length = 756

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VESISLRKA 9
           VES SLRKA
Sbjct: 267 VESTSLRKA 275
>NP_001161090
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VESISLRKA 9
          VES SLRKA
Sbjct: 26 VESTSLRKA 34
>NP_001161089
          Length = 658

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VESISLRKA 9
           VES SLRKA
Sbjct: 169 VESTSLRKA 177
>NP_001245203
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VESISLRKA 9
          VES SLRKA
Sbjct: 26 VESTSLRKA 34
>XP_005265221
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VESISLRKA 9
          VES SLRKA
Sbjct: 26 VESTSLRKA 34
>XP_005265220
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  VESISLRKA 9
          VES SLRKA
Sbjct: 26 VESTSLRKA 34
>NP_003740
          Length = 1338

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    VESISLRKA 9
            VE++SLRK+
Sbjct: 1177 VENVSLRKS 1185
>NP_001013649
          Length = 1225

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ESISLRKA 9
           +SISLRKA
Sbjct: 557 KSISLRKA 564
>XP_006724707
          Length = 1337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ESISLRKA 9
           +SISLRKA
Sbjct: 669 KSISLRKA 676
>NP_065753
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SISLRKA 9
          S+SLRKA
Sbjct: 79 SVSLRKA 85
>NP_001008781
          Length = 4557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    VESISLRK 8
            ++SIS+RK
Sbjct: 1501 IDSISMRK 1508
>XP_006718827
          Length = 3479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VESISLRK 8
           ++SIS+RK
Sbjct: 391 IDSISMRK 398
>XP_006716871
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SISLRKA 9
          S+SLRKA
Sbjct: 79 SVSLRKA 85
>NP_001243888
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESISLRK 8
           +SISLRK
Sbjct: 196 QSISLRK 202
>NP_001277
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESISLRK 8
           +SISLRK
Sbjct: 218 QSISLRK 224
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.121    0.265 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 300,027
Number of extensions: 230
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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