Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              21     229
NP_001075109                                                           21     229
NP_653258                                                              17    3301
NP_001170949                                                           17    3301
NP_001170950                                                           17    3301
XP_006724682                                                           17    3301
XP_005262138                                                           17    3301
NP_005870                                                              17    3301
NP_000375                                                              16    5631
NP_570824                                                              16    5631
NP_055325                                                              16    5631
NP_149015                                                              16    5631
NP_003072                                                              16    5631
XP_006723677                                                           16    5631
XP_005260867                                                           16    5631
XP_005260865                                                           16    5631
XP_006715989                                                           16    5631
NP_001367                                                              16    7355
NP_001002814                                                           16    7355
NP_079427                                                              16    7355
NP_055826                                                              16    7355
NP_001185879                                                           16    7355
NP_055719                                                              16    7355
NP_116253                                                              16    7355
NP_001274324                                                           16    7355
XP_005269686                                                           16    7355
XP_006712547                                                           16    7355
XP_005245779                                                           16    7355
XP_005245778                                                           16    7355
XP_005245777                                                           16    7355
XP_005245776                                                           16    7355
XP_005245775                                                           16    7355
XP_005245774                                                           16    7355
NP_005830                                                              16    7355
NP_060660                                                              15    9605
NP_004645                                                              15    9605
NP_055196                                                              15    9605
NP_001035197                                                           15    9605
NP_078863                                                              15    9605
NP_057454                                                              15    9605
NP_055178                                                              15    9605
NP_001264984                                                           15    9605
NP_789794                                                              15    9605
NP_004242                                                              15    9605
NP_059115                                                              15    9605
NP_001182257                                                           15    9605
XP_006724722                                                           15    9605
XP_006724721                                                           15    9605
XP_006720180                                                           15    9605
XP_005267590                                                           15    9605
XP_005267589                                                           15    9605
XP_005267588                                                           15    9605
XP_006720179                                                           15    9605
XP_005266395                                                           15    9605
XP_005263163                                                           15    9605
XP_005271253                                                           15    9605
XP_005271252                                                           15    9605
XP_005271251                                                           15    9605
>NP_008835
          Length = 4128

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VEFMRNELE 9
            VEF+RNELE
Sbjct: 3692 VEFLRNELE 3700
>NP_001075109
          Length = 4097

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VEFMRNELE 9
            VEF+RNELE
Sbjct: 3692 VEFLRNELE 3700
>NP_653258
          Length = 690

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VEFMRNELE 9
           V+F+ NELE
Sbjct: 612 VKFIENELE 620
>NP_001170949
          Length = 632

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VEFMRNELE 9
           V+F+ NELE
Sbjct: 554 VKFIENELE 562
>NP_001170950
          Length = 690

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VEFMRNELE 9
           V+F+ NELE
Sbjct: 612 VKFIENELE 620
>XP_006724682
          Length = 632

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VEFMRNELE 9
           V+F+ NELE
Sbjct: 554 VKFIENELE 562
>XP_005262138
          Length = 690

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VEFMRNELE 9
           V+F+ NELE
Sbjct: 612 VKFIENELE 620
>NP_005870
          Length = 469

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  EFMRNELE 9
          EF++NEL+
Sbjct: 77 EFLKNELD 84
>NP_000375
          Length = 4563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    EFMRNELE 9
            EF++NEL+
Sbjct: 4361 EFIQNELQ 4368
>NP_570824
          Length = 206

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  MRNELE 9
          MRNELE
Sbjct: 7  MRNELE 12
>NP_055325
          Length = 4935

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    EFMRNELE 9
            EF+RN+L+
Sbjct: 1576 EFIRNQLK 1583
>NP_149015
          Length = 5142

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    EFMRNELE 9
            EF+RN+L+
Sbjct: 1576 EFIRNQLK 1583
>NP_003072
          Length = 206

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  MRNELE 9
          MRNELE
Sbjct: 7  MRNELE 12
>XP_006723677
          Length = 136

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  MRNELE 9
          MRNELE
Sbjct: 7  MRNELE 12
>XP_005260867
          Length = 206

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  MRNELE 9
          MRNELE
Sbjct: 7  MRNELE 12
>XP_005260865
          Length = 206

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  MRNELE 9
          MRNELE
Sbjct: 7  MRNELE 12
>XP_006715989
          Length = 5148

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    EFMRNELE 9
            EF+RN+L+
Sbjct: 1576 EFIRNQLK 1583
>NP_001367
          Length = 4646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VEFMRNELE 9
            VE +RNEL+
Sbjct: 3409 VEPLRNELQ 3417
>NP_001002814
          Length = 1283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VEFMRNEL 8
           ++FMRN +
Sbjct: 146 IQFMRNNM 153
>NP_079427
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VEFMRNEL 8
           ++FMRN +
Sbjct: 146 IQFMRNNM 153
>NP_055826
          Length = 1858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   EFMRNELE 9
           EF +NE E
Sbjct: 784 EFQKNEFE 791
>NP_001185879
          Length = 1880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   EFMRNELE 9
           EF +NE E
Sbjct: 806 EFQKNEFE 813
>NP_055719
          Length = 512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VEFMRNEL 8
           ++FMRN +
Sbjct: 140 IQFMRNNM 147
>NP_116253
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  VEFMRNE 7
          VEF++NE
Sbjct: 88 VEFIKNE 94
>NP_001274324
          Length = 1688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VEFMRNELE 9
           ++F+RN L+
Sbjct: 650 IQFLRNSLK 658
>XP_005269686
          Length = 532

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VEFMRNEL 8
           ++FMRN +
Sbjct: 140 IQFMRNNM 147
>XP_006712547
          Length = 1674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VEFMRNELE 9
           ++F+RN L+
Sbjct: 647 IQFLRNSLK 655
>XP_005245779
          Length = 888

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VEFMRNELE 9
          +EF+ N+LE
Sbjct: 68 IEFIFNQLE 76
>XP_005245778
          Length = 902

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VEFMRNELE 9
          +EF+ N+LE
Sbjct: 68 IEFIFNQLE 76
>XP_005245777
          Length = 915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VEFMRNELE 9
          +EF+ N+LE
Sbjct: 68 IEFIFNQLE 76
>XP_005245776
          Length = 916

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VEFMRNELE 9
          +EF+ N+LE
Sbjct: 68 IEFIFNQLE 76
>XP_005245775
          Length = 917

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VEFMRNELE 9
          +EF+ N+LE
Sbjct: 68 IEFIFNQLE 76
>XP_005245774
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VEFMRNELE 9
          +EF+ N+LE
Sbjct: 68 IEFIFNQLE 76
>NP_005830
          Length = 904

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VEFMRNELE 9
          +EF+ N+LE
Sbjct: 68 IEFIFNQLE 76
>NP_060660
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEFMRNELE 9
           +  +RNELE
Sbjct: 342 ISSLRNELE 350
>NP_004645
          Length = 2555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VEFMRNELE 9
            V+FM N L+
Sbjct: 1997 VKFMHNRLQ 2005
>NP_055196
          Length = 1429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EFMRNELE 9
            EF+R +LE
Sbjct: 1306 EFIREQLE 1313
>NP_001035197
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EFMRNELE 9
            EF+R +LE
Sbjct: 1330 EFIREQLE 1337
>NP_078863
          Length = 277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VEFMRN 6
           V+FMRN
Sbjct: 268 VDFMRN 273
>NP_057454
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VEFMRNELE 9
          VEF+  +LE
Sbjct: 42 VEFLNRDLE 50
>NP_055178
          Length = 4579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VEFMRN 6
            VEF+RN
Sbjct: 3583 VEFLRN 3588
>NP_001264984
          Length = 4432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VEFMRN 6
            VEF+RN
Sbjct: 3436 VEFLRN 3441
>NP_789794
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEFMRNELE 9
           +  +RNELE
Sbjct: 342 ISSLRNELE 350
>NP_004242
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VEFMRNELE 9
          VEF+  +LE
Sbjct: 42 VEFLNKDLE 50
>NP_059115
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VEFMRNE 7
           VEF+RN+
Sbjct: 167 VEFIRNK 173
>NP_001182257
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VEFMRNELE 9
          VEF+  +LE
Sbjct: 42 VEFLNKDLE 50
>XP_006724722
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VEFMRNELE 9
          VEF+  +LE
Sbjct: 42 VEFLNRDLE 50
>XP_006724721
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VEFMRNELE 9
          VEF+  +LE
Sbjct: 42 VEFLNRDLE 50
>XP_006720180
          Length = 269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EFMRNELE 9
           EF+R +LE
Sbjct: 146 EFIREQLE 153
>XP_005267590
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EFMRNELE 9
            EF+R +LE
Sbjct: 1271 EFIREQLE 1278
>XP_005267589
          Length = 1418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EFMRNELE 9
            EF+R +LE
Sbjct: 1295 EFIREQLE 1302
>XP_005267588
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EFMRNELE 9
            EF+R +LE
Sbjct: 1330 EFIREQLE 1337
>XP_006720179
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EFMRNELE 9
            EF+R +LE
Sbjct: 1330 EFIREQLE 1337
>XP_005266395
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    VEFMRN 6
            VEF+RN
Sbjct: 3592 VEFLRN 3597
>XP_005263163
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEFMRNELE 9
           +  +RNELE
Sbjct: 343 ISSLRNELE 351
>XP_005271253
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VEFMRN 6
           V+FMRN
Sbjct: 195 VDFMRN 200
>XP_005271252
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VEFMRN 6
           V+FMRN
Sbjct: 237 VDFMRN 242
>XP_005271251
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VEFMRN 6
           V+FMRN
Sbjct: 238 VDFMRN 243
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.137    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 479,092
Number of extensions: 922
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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