Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              20     509
NP_056162                                                              16    5631
NP_001449                                                              16    7355
NP_001120959                                                           16    7355
NP_004550                                                              16    7355
NP_705838                                                              16    7355
NP_001138898                                                           16    7355
NP_056121                                                              16    7355
NP_057030                                                              16    7355
NP_003642                                                              16    7355
XP_006715973                                                           16    7355
XP_006714302                                                           16    7355
XP_005263127                                                           16    7355
XP_005270747                                                           16    7355
XP_006710574                                                           16    7355
XP_005270746                                                           16    7355
NP_057066                                                              16    7355
NP_061908                                                              16    7355
NP_057336                                                              15    9605
NP_001245204                                                           15    9605
NP_055068                                                              15    9605
NP_001128360                                                           15    9605
NP_001156750                                                           15    9605
NP_073619                                                              15    9605
NP_001156751                                                           15    9605
NP_775099                                                              15    9605
NP_001017373                                                           15    9605
NP_056472                                                              15    9605
NP_005727                                                              15    9605
NP_001264114                                                           15    9605
NP_002544                                                              15    9605
XP_006724788                                                           15    9605
XP_005259877                                                           15    9605
XP_006719250                                                           15    9605
XP_005266885                                                           15    9605
XP_006712120                                                           15    9605
XP_005264512                                                           15    9605
XP_005264511                                                           15    9605
XP_006712119                                                           15    9605
XP_005264510                                                           15    9605
XP_006712118                                                           15    9605
XP_005264509                                                           15    9605
XP_005264508                                                           15    9605
XP_006712117                                                           15    9605
XP_005264507                                                           15    9605
XP_005264506                                                           15    9605
NP_055790                                                              15    9605
>NP_004251
          Length = 1208

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VEFDIVKLV 9
           VEFD+VKLV
Sbjct: 985 VEFDMVKLV 993
>NP_056162
          Length = 1052

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   EFDIVK 7
           EFDIVK
Sbjct: 428 EFDIVK 433
>NP_001449
          Length = 2725

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   VEFDIVK 7
           ++FDI+K
Sbjct: 817 IDFDIIK 823
>NP_001120959
          Length = 2692

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   VEFDIVK 7
           ++FDI+K
Sbjct: 817 IDFDIIK 823
>NP_004550
          Length = 324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VEFDIVK 7
           VEFD+V+
Sbjct: 109 VEFDVVE 115
>NP_705838
          Length = 4069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    EFDIVKL 8
            E+D+VKL
Sbjct: 3105 EYDLVKL 3111
>NP_001138898
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VEFDIVK 7
           VEFD+V+
Sbjct: 141 VEFDVVE 147
>NP_056121
          Length = 2620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FDIVKLV 9
           F+IVKLV
Sbjct: 666 FEIVKLV 672
>NP_057030
          Length = 385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VEFDIVKLV 9
           + FD+VK +
Sbjct: 197 IHFDVVKCI 205
>NP_003642
          Length = 372

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VEFDIVK 7
           VEFD+V+
Sbjct: 141 VEFDVVE 147
>XP_006715973
          Length = 2632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   VEFDIVK 7
           ++FDI+K
Sbjct: 817 IDFDIIK 823
>XP_006714302
          Length = 916

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VEFDIVKL 8
           +EFD++ L
Sbjct: 106 IEFDVITL 113
>XP_005263127
          Length = 1134

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VEFDIVKL 8
           +EFD++ L
Sbjct: 106 IEFDVITL 113
>XP_005270747
          Length = 2025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  FDIVKLV 9
          F+IVKLV
Sbjct: 71 FEIVKLV 77
>XP_006710574
          Length = 2445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FDIVKLV 9
           F+IVKLV
Sbjct: 491 FEIVKLV 497
>XP_005270746
          Length = 2443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FDIVKLV 9
           F+IVKLV
Sbjct: 491 FEIVKLV 497
>NP_057066
          Length = 364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VEFDIVK 7
           VEFD+V+
Sbjct: 144 VEFDVVE 150
>NP_061908
          Length = 1135

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   VEFDIVKL 8
           +EFD++ L
Sbjct: 106 IEFDVITL 113
>NP_057336
          Length = 4857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2920 FDLLKLV 2926
>NP_001245204
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEFDIVKLV 9
           + FD +KLV
Sbjct: 263 IRFDEIKLV 271
>NP_055068
          Length = 2725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EFDIVKLV 9
           +FD VKL+
Sbjct: 456 QFDFVKLM 463
>NP_001128360
          Length = 1358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   VEFDIV 6
           +EFDIV
Sbjct: 490 IEFDIV 495
>NP_001156750
          Length = 2732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EFDIVKLV 9
           +FD VKL+
Sbjct: 456 QFDFVKLM 463
>NP_073619
          Length = 1183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2 EFDIVK 7
         EFD+VK
Sbjct: 3 EFDLVK 8
>NP_001156751
          Length = 2731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EFDIVKLV 9
           +FD VKL+
Sbjct: 455 QFDFVKLM 462
>NP_775099
          Length = 2595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    EFDIVKL 8
            EFD+V+L
Sbjct: 2250 EFDLVQL 2256
>NP_001017373
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEFDIVKLV 9
           + FD +KLV
Sbjct: 263 IRFDEIKLV 271
>NP_056472
          Length = 2277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    EFDIVKL 8
            EFD+V+L
Sbjct: 1932 EFDLVQL 1938
>NP_005727
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EFDIVKLV 9
           EF+IVK +
Sbjct: 210 EFEIVKAI 217
>NP_001264114
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEFDIVKLV 9
           + FD +KLV
Sbjct: 287 IRFDEIKLV 295
>NP_002544
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VEFDIVK 7
           V FDI+K
Sbjct: 423 VNFDIIK 429
>XP_006724788
          Length = 2570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EFDIVKLV 9
           +FD VKL+
Sbjct: 302 QFDFVKLM 309
>XP_005259877
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   EFDIVKLV 9
           +FD +KL+
Sbjct: 197 DFDTIKLI 204
>XP_006719250
          Length = 1141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2 EFDIVK 7
         EFD+VK
Sbjct: 3 EFDLVK 8
>XP_005266885
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VEFDIVKLV 9
           + FD +KLV
Sbjct: 283 IRFDEIKLV 291
>XP_006712120
          Length = 4812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2875 FDLLKLV 2881
>XP_005264512
          Length = 4840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2903 FDLLKLV 2909
>XP_005264511
          Length = 4847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2947 FDLLKLV 2953
>XP_006712119
          Length = 4851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2914 FDLLKLV 2920
>XP_005264510
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2924 FDLLKLV 2930
>XP_006712118
          Length = 4864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2947 FDLLKLV 2953
>XP_005264509
          Length = 4870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2933 FDLLKLV 2939
>XP_005264508
          Length = 4875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2938 FDLLKLV 2944
>XP_006712117
          Length = 4878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2941 FDLLKLV 2947
>XP_005264507
          Length = 4880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2943 FDLLKLV 2949
>XP_005264506
          Length = 4884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FDIVKLV 9
            FD++KLV
Sbjct: 2947 FDLLKLV 2953
>NP_055790
          Length = 1570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   EFDIVKLV 9
           +FD +KL+
Sbjct: 373 DFDTIKLI 380
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.157    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 390,331
Number of extensions: 565
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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