Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     665
NP_009297                                                              19     665
NP_001360                                                              17    3301
XP_005248319                                                           17    3301
NP_001268639                                                           16    5631
NP_001268640                                                           16    5631
NP_055638                                                              16    5631
NP_998820                                                              16    5631
NP_001171914                                                           16    5631
NP_061852                                                              16    5631
NP_056156                                                              16    5631
NP_001268641                                                           16    5631
XP_006719067                                                           16    5631
XP_006719066                                                           16    5631
XP_005253800                                                           16    5631
XP_005253798                                                           16    5631
XP_005253797                                                           16    5631
XP_005253796                                                           16    5631
XP_006719065                                                           16    5631
XP_006719064                                                           16    5631
XP_006719063                                                           16    5631
XP_006719062                                                           16    5631
XP_005253795                                                           16    5631
XP_005253794                                                           16    5631
XP_005253793                                                           16    5631
XP_005253792                                                           16    5631
XP_006719061                                                           16    5631
XP_005253791                                                           16    5631
XP_006712451                                                           16    5631
XP_005263965                                                           16    5631
XP_005263964                                                           16    5631
NP_001188386                                                           15    9605
NP_938207                                                              15    9605
NP_112562                                                              15    9605
NP_872286                                                              15    9605
NP_055949                                                              15    9605
NP_958431                                                              15    9605
NP_872282                                                              15    9605
XP_006722041                                                           15    9605
XP_005257576                                                           15    9605
XP_006722040                                                           15    9605
XP_006722039                                                           15    9605
XP_005257575                                                           15    9605
XP_005256621                                                           15    9605
XP_006721553                                                           15    9605
XP_006721552                                                           15    9605
XP_006721551                                                           15    9605
XP_006721550                                                           15    9605
XP_005256620                                                           15    9605
XP_005267776                                                           15    9605
XP_005267775                                                           15    9605
XP_006720219                                                           15    9605
XP_005267773                                                           15    9605
>NP_005148
          Length = 1130

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VDAVNSD A
Sbjct: 938 VDAVNSDAA 946
>NP_009297
          Length = 1149

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VDAVNSD A
Sbjct: 957 VDAVNSDAA 965
>NP_001360
          Length = 4624

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            +D +NSD+A
Sbjct: 3045 IDEINSDLA 3053
>XP_005248319
          Length = 4609

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            +D +NSD+A
Sbjct: 3030 IDEINSDLA 3038
>NP_001268639
          Length = 730

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VDAVNSDV 8
           VDAV++DV
Sbjct: 158 VDAVHADV 165
>NP_001268640
          Length = 717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VDAVNSDV 8
           VDAV++DV
Sbjct: 145 VDAVHADV 152
>NP_055638
          Length = 2134

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VD+ +SDVA
Sbjct: 821 VDSAHSDVA 829
>NP_998820
          Length = 2634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            VD+ +SDVA
Sbjct: 1320 VDSAHSDVA 1328
>NP_001171914
          Length = 2642

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            VD+ +SDVA
Sbjct: 1328 VDSAHSDVA 1336
>NP_061852
          Length = 2382

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            VD+ +SDVA
Sbjct: 1068 VDSAHSDVA 1076
>NP_056156
          Length = 741

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VDAVNSDV 8
           VDAV++DV
Sbjct: 169 VDAVHADV 176
>NP_001268641
          Length = 605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  VDAVNSDV 8
          VDAV++DV
Sbjct: 33 VDAVHADV 40
>XP_006719067
          Length = 2228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VD+ +SDVA
Sbjct: 914 VDSAHSDVA 922
>XP_006719066
          Length = 2381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            VD+ +SDVA
Sbjct: 1067 VDSAHSDVA 1075
>XP_005253800
          Length = 2013

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VD+ +SDVA
Sbjct: 661 VDSAHSDVA 669
>XP_005253798
          Length = 2145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VD+ +SDVA
Sbjct: 793 VDSAHSDVA 801
>XP_005253797
          Length = 2146

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VD+ +SDVA
Sbjct: 794 VDSAHSDVA 802
>XP_005253796
          Length = 2173

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VD+ +SDVA
Sbjct: 821 VDSAHSDVA 829
>XP_006719065
          Length = 2174

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VD+ +SDVA
Sbjct: 822 VDSAHSDVA 830
>XP_006719064
          Length = 2229

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VD+ +SDVA
Sbjct: 915 VDSAHSDVA 923
>XP_006719063
          Length = 2266

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VD+ +SDVA
Sbjct: 914 VDSAHSDVA 922
>XP_006719062
          Length = 2267

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VDAVNSDVA 9
           VD+ +SDVA
Sbjct: 915 VDSAHSDVA 923
>XP_005253795
          Length = 2280

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            VD+ +SDVA
Sbjct: 1068 VDSAHSDVA 1076
>XP_005253794
          Length = 2391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            VD+ +SDVA
Sbjct: 1039 VDSAHSDVA 1047
>XP_005253793
          Length = 2392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            VD+ +SDVA
Sbjct: 1040 VDSAHSDVA 1048
>XP_005253792
          Length = 2419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            VD+ +SDVA
Sbjct: 1068 VDSAHSDVA 1076
>XP_006719061
          Length = 2419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            VD+ +SDVA
Sbjct: 1067 VDSAHSDVA 1075
>XP_005253791
          Length = 2420

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    VDAVNSDVA 9
            VD+ +SDVA
Sbjct: 1068 VDSAHSDVA 1076
>XP_006712451
          Length = 710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VDAVNSDV 8
           VDAV++DV
Sbjct: 169 VDAVHADV 176
>XP_005263965
          Length = 725

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VDAVNSDV 8
           VDAV++DV
Sbjct: 169 VDAVHADV 176
>XP_005263964
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VDAVNSDV 8
           VDAV++DV
Sbjct: 166 VDAVHADV 173
>NP_001188386
          Length = 1497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  VDAVNS 6
          VDAVNS
Sbjct: 49 VDAVNS 54
>NP_938207
          Length = 1491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  VDAVNS 6
          VDAVNS
Sbjct: 49 VDAVNS 54
>NP_112562
          Length = 1451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  VDAVNS 6
          VDAVNS
Sbjct: 49 VDAVNS 54
>NP_872286
          Length = 443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VDAVNS 6
           VDAVNS
Sbjct: 265 VDAVNS 270
>NP_055949
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VDAVNSDV 8
           + +VNSDV
Sbjct: 795 ISSVNSDV 802
>NP_958431
          Length = 1025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VDAVNSDV 8
           + +VNSDV
Sbjct: 795 ISSVNSDV 802
>NP_872282
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VDAVNS 6
           VDAVNS
Sbjct: 290 VDAVNS 295
>XP_006722041
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  VDAVNS 6
          VDAVNS
Sbjct: 52 VDAVNS 57
>XP_005257576
          Length = 1454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  VDAVNS 6
          VDAVNS
Sbjct: 52 VDAVNS 57
>XP_006722040
          Length = 1466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  VDAVNS 6
          VDAVNS
Sbjct: 52 VDAVNS 57
>XP_006722039
          Length = 1491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  VDAVNS 6
          VDAVNS
Sbjct: 49 VDAVNS 54
>XP_005257575
          Length = 1494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  VDAVNS 6
          VDAVNS
Sbjct: 52 VDAVNS 57
>XP_005256621
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VDAVNSDV 8
           + +VNSDV
Sbjct: 789 ISSVNSDV 796
>XP_006721553
          Length = 2286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VDAVNSDV 8
            + +VNSDV
Sbjct: 2096 ISSVNSDV 2103
>XP_006721552
          Length = 2299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VDAVNSDV 8
            + +VNSDV
Sbjct: 2096 ISSVNSDV 2103
>XP_006721551
          Length = 2301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VDAVNSDV 8
            + +VNSDV
Sbjct: 2058 ISSVNSDV 2065
>XP_006721550
          Length = 2326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VDAVNSDV 8
            + +VNSDV
Sbjct: 2096 ISSVNSDV 2103
>XP_005256620
          Length = 2339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    VDAVNSDV 8
            + +VNSDV
Sbjct: 2096 ISSVNSDV 2103
>XP_005267776
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VDAVNS 6
           VDAVNS
Sbjct: 110 VDAVNS 115
>XP_005267775
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VDAVNS 6
           VDAVNS
Sbjct: 110 VDAVNS 115
>XP_006720219
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VDAVNS 6
           VDAVNS
Sbjct: 181 VDAVNS 186
>XP_005267773
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VDAVNS 6
           VDAVNS
Sbjct: 235 VDAVNS 240
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.118    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 391,468
Number of extensions: 559
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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