Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_006725230                                                           17    4312
XP_006720283                                                           17    4312
NP_001275563                                                           16    7355
NP_060652                                                              16    7355
NP_001275567                                                           16    7355
NP_001070966                                                           16    7355
NP_001275560                                                           16    7355
NP_001275562                                                           16    7355
NP_001275565                                                           16    7355
NP_001275566                                                           16    7355
NP_001275569                                                           16    7355
NP_001275561                                                           16    7355
NP_001275568                                                           16    7355
NP_001275564                                                           16    7355
NP_060104                                                              16    7355
XP_006722034                                                           16    7355
NP_001160060                                                           15    9605
NP_055587                                                              15    9605
NP_001135869                                                           15    9605
NP_001248347                                                           15    9605
NP_065098                                                              15    9605
XP_006722652                                                           15    9605
XP_006722651                                                           15    9605
XP_006722650                                                           15    9605
XP_006722649                                                           15    9605
XP_006722648                                                           15    9605
XP_006722647                                                           15    9605
XP_006722646                                                           15    9605
XP_005258449                                                           15    9605
>XP_006725230
          Length = 2636

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   TVTRSLL 7
           TVTRSLL
Sbjct: 94  TVTRSLL 100
>XP_006720283
          Length = 2636

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   TVTRSLL 7
           TVTRSLL
Sbjct: 94  TVTRSLL 100
>NP_001275563
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_060652
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_001275567
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 170 ISRSLLIN 177
>NP_001070966
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_001275560
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 300 ISRSLLIN 307
>NP_001275562
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_001275565
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 170 ISRSLLIN 177
>NP_001275566
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 170 ISRSLLIN 177
>NP_001275569
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 170 ISRSLLIN 177
>NP_001275561
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_001275568
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 170 ISRSLLIN 177
>NP_001275564
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 298 ISRSLLIN 305
>NP_060104
          Length = 389

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T TRS L+N
Sbjct: 101 TTTRSTLVN 109
>XP_006722034
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTRSLLLN 9
           ++RSLL+N
Sbjct: 300 ISRSLLIN 307
>NP_001160060
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T+T  LL+N
Sbjct: 386 TITNCLLMN 394
>NP_055587
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T  RSLLLN
Sbjct: 446 TKFRSLLLN 454
>NP_001135869
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T  RSLLLN
Sbjct: 448 TKFRSLLLN 456
>NP_001248347
          Length = 401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T+T  LL+N
Sbjct: 386 TITNCLLMN 394
>NP_065098
          Length = 452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T+T  LL+N
Sbjct: 386 TITNCLLMN 394
>XP_006722652
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T  RSLLLN
Sbjct: 448 TKFRSLLLN 456
>XP_006722651
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T  RSLLLN
Sbjct: 448 TKFRSLLLN 456
>XP_006722650
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T  RSLLLN
Sbjct: 448 TKFRSLLLN 456
>XP_006722649
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T  RSLLLN
Sbjct: 462 TKFRSLLLN 470
>XP_006722648
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T  RSLLLN
Sbjct: 464 TKFRSLLLN 472
>XP_006722647
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T  RSLLLN
Sbjct: 464 TKFRSLLLN 472
>XP_006722646
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T  RSLLLN
Sbjct: 464 TKFRSLLLN 472
>XP_005258449
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TVTRSLLLN 9
           T  RSLLLN
Sbjct: 464 TKFRSLLLN 472
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.131    0.317 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 308,926
Number of extensions: 370
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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