Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              19     665
NP_001008895                                                           17    3301
NP_001265442                                                           17    3301
NP_001265443                                                           17    3301
NP_003580                                                              17    3301
XP_005263881                                                           17    4312
NP_115685                                                              17    4312
NP_065896                                                              16    5631
NP_055077                                                              16    5631
XP_006719582                                                           16    5631
XP_005253643                                                           16    5631
XP_005253642                                                           16    5631
XP_006719581                                                           16    5631
XP_006719580                                                           16    5631
XP_005253640                                                           16    5631
XP_006719579                                                           16    5631
XP_005253639                                                           16    5631
XP_006711533                                                           16    5631
XP_005245422                                                           16    5631
NP_065821                                                              16    5631
NP_542168                                                              16    7355
NP_001008275                                                           16    7355
NP_597716                                                              16    7355
NP_002825                                                              16    7355
NP_001269779                                                           16    7355
NP_065196                                                              16    7355
NP_001116436                                                           16    7355
NP_009146                                                              16    7355
NP_054872                                                              16    7355
XP_005276341                                                           16    7355
XP_005266706                                                           16    7355
XP_005266705                                                           16    7355
XP_006722456                                                           16    7355
XP_005255330                                                           16    7355
XP_005255329                                                           16    7355
XP_006720940                                                           16    7355
XP_005255327                                                           16    7355
XP_006719590                                                           16    7355
XP_006719589                                                           16    7355
XP_005249982                                                           16    7355
XP_006712581                                                           16    7355
XP_005246132                                                           16    7355
XP_005264503                                                           16    7355
XP_005264502                                                           16    7355
XP_005264501                                                           16    7355
XP_005264499                                                           16    7355
XP_005276054                                                           16    7355
NP_001073973                                                           16    7355
NP_055919                                                              15    9605
NP_006412                                                              15    9605
NP_006411                                                              15    9605
NP_821174                                                              15    9605
NP_003120                                                              15    9605
NP_060340                                                              15    9605
XP_005260309                                                           15    9605
XP_005273907                                                           15    9605
XP_005273906                                                           15    9605
XP_005251193                                                           15    9605
XP_005251192                                                           15    9605
XP_005251191                                                           15    9605
XP_005245197                                                           15    9605
XP_005245196                                                           15    9605
NP_001186910                                                           15    9605
>NP_004295
          Length = 1620

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TVLQLRQAC 9
           TVLQL QAC
Sbjct: 447 TVLQLGQAC 455
>NP_001008895
          Length = 759

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QLRQAC 9
           QLRQAC
Sbjct: 105 QLRQAC 110
>NP_001265442
          Length = 659

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  QLRQAC 9
          QLRQAC
Sbjct: 5  QLRQAC 10
>NP_001265443
          Length = 667

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  QLRQAC 9
          QLRQAC
Sbjct: 5  QLRQAC 10
>NP_003580
          Length = 659

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  QLRQAC 9
          QLRQAC
Sbjct: 5  QLRQAC 10
>XP_005263881
          Length = 158

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VLQLRQAC 9
          + Q+RQAC
Sbjct: 51 IRQIRQAC 58
>NP_115685
          Length = 110

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VLQLRQAC 9
          + Q+RQAC
Sbjct: 51 IRQIRQAC 58
>NP_065896
          Length = 1349

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLQLRQAC 9
           V QLR AC
Sbjct: 745 VFQLRPAC 752
>NP_055077
          Length = 736

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLQLRQAC 9
           VLQ RQ C
Sbjct: 290 VLQCRQRC 297
>XP_006719582
          Length = 1295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLQLRQAC 9
           V QLR AC
Sbjct: 745 VFQLRPAC 752
>XP_005253643
          Length = 1331

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLQLRQAC 9
           V QLR AC
Sbjct: 679 VFQLRPAC 686
>XP_005253642
          Length = 1343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLQLRQAC 9
           V QLR AC
Sbjct: 745 VFQLRPAC 752
>XP_006719581
          Length = 1380

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLQLRQAC 9
           V QLR AC
Sbjct: 728 VFQLRPAC 735
>XP_006719580
          Length = 1381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLQLRQAC 9
           V QLR AC
Sbjct: 729 VFQLRPAC 736
>XP_005253640
          Length = 1397

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLQLRQAC 9
           V QLR AC
Sbjct: 745 VFQLRPAC 752
>XP_006719579
          Length = 1397

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLQLRQAC 9
           V QLR AC
Sbjct: 745 VFQLRPAC 752
>XP_005253639
          Length = 1397

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VLQLRQAC 9
           V QLR AC
Sbjct: 745 VFQLRPAC 752
>XP_006711533
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVLQLRQAC 9
           T+ QLRQ C
Sbjct: 689 TLQQLRQDC 697
>XP_005245422
          Length = 1203

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVLQLRQAC 9
           T+ QLRQ C
Sbjct: 689 TLQQLRQDC 697
>NP_065821
          Length = 1203

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVLQLRQAC 9
           T+ QLRQ C
Sbjct: 689 TLQQLRQDC 697
>NP_542168
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TVLQLRQ 7
           TVLQL+Q
Sbjct: 208 TVLQLKQ 214
>NP_001008275
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LQLRQAC 9
           LQL++AC
Sbjct: 138 LQLQEAC 144
>NP_597716
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TVLQLRQ 7
           TVLQL+Q
Sbjct: 211 TVLQLKQ 217
>NP_002825
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TVLQLRQ 7
           TVLQL+Q
Sbjct: 208 TVLQLKQ 214
>NP_001269779
          Length = 817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLQLRQAC 9
           +LQL QAC
Sbjct: 175 LLQLFQAC 182
>NP_065196
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLQLRQAC 9
           +LQL QAC
Sbjct: 175 LLQLFQAC 182
>NP_001116436
          Length = 849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLQLRQAC 9
           +LQL QAC
Sbjct: 175 LLQLFQAC 182
>NP_009146
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LQLRQAC 9
           L+LRQ C
Sbjct: 393 LELRQVC 399
>NP_054872
          Length = 971

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QLRQAC 9
           +LRQAC
Sbjct: 441 ELRQAC 446
>XP_005276341
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QLRQAC 9
           QLRQ+C
Sbjct: 189 QLRQSC 194
>XP_005266706
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  TVLQLRQ 7
          TVLQL+Q
Sbjct: 20 TVLQLKQ 26
>XP_005266705
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TVLQLRQ 7
           TVLQL+Q
Sbjct: 211 TVLQLKQ 217
>XP_006722456
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TVLQLRQ 7
           TVLQL+Q
Sbjct: 211 TVLQLKQ 217
>XP_005255330
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLRQAC 9
          +LRQAC
Sbjct: 50 ELRQAC 55
>XP_005255329
          Length = 958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QLRQAC 9
           +LRQAC
Sbjct: 428 ELRQAC 433
>XP_006720940
          Length = 971

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QLRQAC 9
           +LRQAC
Sbjct: 441 ELRQAC 446
>XP_005255327
          Length = 971

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QLRQAC 9
           +LRQAC
Sbjct: 441 ELRQAC 446
>XP_006719590
          Length = 559

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TVLQLRQ 7
           TVLQL+Q
Sbjct: 208 TVLQLKQ 214
>XP_006719589
          Length = 597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TVLQLRQ 7
           TVLQL+Q
Sbjct: 208 TVLQLKQ 214
>XP_005249982
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QLRQAC 9
           QLRQ+C
Sbjct: 189 QLRQSC 194
>XP_006712581
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LQLRQAC 9
           L+LR+AC
Sbjct: 563 LELRKAC 569
>XP_005246132
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LQLRQAC 9
           L+LR+AC
Sbjct: 563 LELRKAC 569
>XP_005264503
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLQLRQAC 9
           +LQL QAC
Sbjct: 175 LLQLFQAC 182
>XP_005264502
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLQLRQAC 9
           +LQL QAC
Sbjct: 175 LLQLFQAC 182
>XP_005264501
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLQLRQAC 9
           +LQL QAC
Sbjct: 175 LLQLFQAC 182
>XP_005264499
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLQLRQAC 9
           +LQL QAC
Sbjct: 175 LLQLFQAC 182
>XP_005276054
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QLRQAC 9
           QLRQ+C
Sbjct: 189 QLRQSC 194
>NP_001073973
          Length = 1052

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LQLRQAC 9
           L+LR+AC
Sbjct: 563 LELRKAC 569
>NP_055919
          Length = 1938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TVLQLRQAC 9
           T LQL Q C
Sbjct: 127 TSLQLAQEC 135
>NP_006412
          Length = 1849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLRQAC 9
          QLR+AC
Sbjct: 32 QLRKAC 37
>NP_006411
          Length = 1785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLRQAC 9
          QLR+AC
Sbjct: 31 QLRRAC 36
>NP_821174
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VLQLRQAC 9
           VLQ+ +AC
Sbjct: 450 VLQVSEAC 457
>NP_003120
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QLRQAC 9
           QLR+AC
Sbjct: 486 QLRKAC 491
>NP_060340
          Length = 1024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VLQLRQAC 9
           VLQ+ +AC
Sbjct: 451 VLQVSEAC 458
>XP_005260309
          Length = 1784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLRQAC 9
          QLR+AC
Sbjct: 31 QLRRAC 36
>XP_005273907
          Length = 1930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TVLQLRQAC 9
           T LQL Q C
Sbjct: 127 TSLQLAQEC 135
>XP_005273906
          Length = 1932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TVLQLRQAC 9
           T LQL Q C
Sbjct: 127 TSLQLAQEC 135
>XP_005251193
          Length = 1800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLRQAC 9
          QLR+AC
Sbjct: 32 QLRKAC 37
>XP_005251192
          Length = 1843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLRQAC 9
          QLR+AC
Sbjct: 32 QLRKAC 37
>XP_005251191
          Length = 1849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QLRQAC 9
          QLR+AC
Sbjct: 32 QLRKAC 37
>XP_005245197
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VLQLRQA 8
           +LQ+RQA
Sbjct: 300 ILQMRQA 306
>XP_005245196
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VLQLRQA 8
           +LQ+RQA
Sbjct: 300 ILQMRQA 306
>NP_001186910
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TVLQLRQAC 9
          TVLQ+  AC
Sbjct: 48 TVLQVVAAC 56
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 413,515
Number of extensions: 559
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package