Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055726                                                              18    1482
NP_444511                                                              18    1935
NP_001132986                                                           18    1935
NP_001132987                                                           18    1935
XP_005262125                                                           18    1935
NP_055318                                                              17    3301
NP_071940                                                              17    3301
XP_005268066                                                           17    3301
XP_006719406                                                           17    3301
NP_085132                                                              16    5631
NP_004438                                                              16    5631
NP_938204                                                              16    5631
NP_001229241                                                           16    5631
NP_659456                                                              16    5631
XP_006721348                                                           16    5631
XP_005256239                                                           16    5631
XP_005256238                                                           16    5631
XP_005256236                                                           16    5631
XP_006719120                                                           16    5631
XP_005253397                                                           16    5631
XP_005253396                                                           16    5631
NP_004613                                                              16    5631
NP_065941                                                              16    7355
NP_001164231                                                           16    7355
NP_001164232                                                           16    7355
NP_055185                                                              16    7355
NP_055975                                                              16    7355
NP_057274                                                              16    7355
NP_714916                                                              16    7355
NP_055959                                                              16    7355
NP_036376                                                              16    7355
NP_060517                                                              16    7355
XP_005255915                                                           16    7355
XP_005266116                                                           16    7355
XP_005268536                                                           16    7355
XP_006713780                                                           16    7355
XP_005247739                                                           16    7355
XP_006713779                                                           16    7355
XP_006711409                                                           16    7355
NP_001128530                                                           15    9605
NP_004077                                                              15    9605
NP_937762                                                              15    9605
NP_001121190                                                           15    9605
NP_000218                                                              15    9605
NP_001121189                                                           15    9605
NP_777576                                                              15    9605
NP_443134                                                              15    9605
XP_006720136                                                           15    9605
XP_006719093                                                           15    9605
XP_006715232                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
>NP_055726
          Length = 961

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TVDSGLRLL 9
           TVDSGL LL
Sbjct: 765 TVDSGLPLL 773
>NP_444511
          Length = 599

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVDSGLRLL 9
           T DSGLR+L
Sbjct: 552 TSDSGLRML 560
>NP_001132986
          Length = 571

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVDSGLRLL 9
           T DSGLR+L
Sbjct: 539 TSDSGLRML 547
>NP_001132987
          Length = 432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVDSGLRLL 9
           T DSGLR+L
Sbjct: 385 TSDSGLRML 393
>XP_005262125
          Length = 465

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TVDSGLRLL 9
           T DSGLR+L
Sbjct: 418 TSDSGLRML 426
>NP_055318
          Length = 2785

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VDSGLRLL 9
            ++SGLRLL
Sbjct: 2084 IESGLRLL 2091
>NP_071940
          Length = 938

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TVDSGLRLL 9
           ++D+GLRLL
Sbjct: 283 SLDTGLRLL 291
>XP_005268066
          Length = 1172

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TVDSGLRLL 9
           ++D+GLRLL
Sbjct: 517 SLDTGLRLL 525
>XP_006719406
          Length = 2380

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VDSGLRLL 9
            ++SGLRLL
Sbjct: 2084 IESGLRLL 2091
>NP_085132
          Length = 679

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSGLRLL 9
           D+GLRLL
Sbjct: 606 DAGLRLL 612
>NP_004438
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TVDSGLRLL 9
          TVD G+R L
Sbjct: 83 TVDDGIRKL 91
>NP_938204
          Length = 773

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSGLRLL 9
           D+GLRLL
Sbjct: 700 DAGLRLL 706
>NP_001229241
          Length = 546

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VDSGLRL 8
           VD+GLRL
Sbjct: 414 VDTGLRL 420
>NP_659456
          Length = 582

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VDSGLRL 8
           VD+GLRL
Sbjct: 450 VDTGLRL 456
>XP_006721348
          Length = 586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSGLRLL 9
           D+GLRLL
Sbjct: 513 DAGLRLL 519
>XP_005256239
          Length = 586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSGLRLL 9
           D+GLRLL
Sbjct: 513 DAGLRLL 519
>XP_005256238
          Length = 586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSGLRLL 9
           D+GLRLL
Sbjct: 513 DAGLRLL 519
>XP_005256236
          Length = 737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSGLRLL 9
           D+GLRLL
Sbjct: 664 DAGLRLL 670
>XP_006719120
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TVDSGLRLL 9
          TVD G+R L
Sbjct: 83 TVDDGIRKL 91
>XP_005253397
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TVDSGLRLL 9
          TVD G+R L
Sbjct: 83 TVDDGIRKL 91
>XP_005253396
          Length = 833

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TVDSGLRLL 9
           TVD G+R L
Sbjct: 94  TVDDGIRKL 102
>NP_004613
          Length = 228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VDSGLRLL 9
           +DSG RLL
Sbjct: 177 LDSGFRLL 184
>NP_065941
          Length = 905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VDSGLRLL 9
           V SGLR+L
Sbjct: 525 VQSGLRIL 532
>NP_001164231
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DSGLRL 8
           DSGLRL
Sbjct: 302 DSGLRL 307
>NP_001164232
          Length = 533

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DSGLRL 8
           DSGLRL
Sbjct: 302 DSGLRL 307
>NP_055185
          Length = 567

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DSGLRL 8
           DSGLRL
Sbjct: 303 DSGLRL 308
>NP_055975
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  TVDSGLRL 8
          T+D+GLR+
Sbjct: 71 TLDNGLRV 78
>NP_057274
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TVDSGLRLL 9
          TVD  LRLL
Sbjct: 53 TVDEVLRLL 61
>NP_714916
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TVDSGLRL 8
           TVD GL++
Sbjct: 109 TVDEGLKI 116
>NP_055959
          Length = 949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VDSGLRLL 9
           +DSGLR L
Sbjct: 175 LDSGLRYL 182
>NP_036376
          Length = 535

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DSGLRLL 9
           +SGLRLL
Sbjct: 158 ESGLRLL 164
>NP_060517
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TVDSGLRL 8
           T DSG++L
Sbjct: 318 TTDSGIKL 325
>XP_005255915
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VDSGLRLL 9
           +DSGLR L
Sbjct: 312 LDSGLRYL 319
>XP_005266116
          Length = 563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  TVDSGLRL 8
          T+D+GLR+
Sbjct: 71 TLDNGLRV 78
>XP_005268536
          Length = 539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TVDSGLRL 8
           T DSG++L
Sbjct: 437 TTDSGIKL 444
>XP_006713780
          Length = 746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VDSGLRLL 9
           V SGLR+L
Sbjct: 366 VQSGLRIL 373
>XP_005247739
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VDSGLRLL 9
           V SGLR+L
Sbjct: 525 VQSGLRIL 532
>XP_006713779
          Length = 904

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VDSGLRLL 9
           V SGLR+L
Sbjct: 524 VQSGLRIL 531
>XP_006711409
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  TVDSGLRLL 9
          TVD  LRLL
Sbjct: 53 TVDEVLRLL 61
>NP_001128530
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TVDSGLR 7
           TVD+G+R
Sbjct: 257 TVDAGVR 263
>NP_004077
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TVDSGLR 7
           TVD+G+R
Sbjct: 257 TVDAGVR 263
>NP_937762
          Length = 3333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            +SGLRLL
Sbjct: 2857 NSGLRLL 2863
>NP_001121190
          Length = 1668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            +SGLRLL
Sbjct: 1192 NSGLRLL 1198
>NP_000218
          Length = 1724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            +SGLRLL
Sbjct: 1248 NSGLRLL 1254
>NP_001121189
          Length = 3277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            +SGLRLL
Sbjct: 2801 NSGLRLL 2807
>NP_777576
          Length = 1749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    TVDSGLRL 8
            TVD+GL L
Sbjct: 1453 TVDTGLPL 1460
>NP_443134
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VDSGLRLL 9
           +DS LRLL
Sbjct: 189 LDSSLRLL 196
>XP_006720136
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TVDSGLR 7
           TVD+G+R
Sbjct: 257 TVDAGVR 263
>XP_006719093
          Length = 471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VDSGLRL 8
           VDSGL++
Sbjct: 453 VDSGLKI 459
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1581 DTGIRLL 1587
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1255 DTGIRLL 1261
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1581 DTGIRLL 1587
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1607 DTGIRLL 1613
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1614 DTGIRLL 1620
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1621 DTGIRLL 1627
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1654 DTGIRLL 1660
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1792 DTGIRLL 1798
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1697 DTGIRLL 1703
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1759 DTGIRLL 1765
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1792 DTGIRLL 1798
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1792 DTGIRLL 1798
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1771 DTGIRLL 1777
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1792 DTGIRLL 1798
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    DSGLRLL 9
            D+G+RLL
Sbjct: 1792 DTGIRLL 1798
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.145    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 509,689
Number of extensions: 892
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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