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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              20     509
NP_001243397                                                           20     509
XP_005269721                                                           20     509
NP_056078                                                              17    2528
NP_689845                                                              17    2528
NP_001167587                                                           17    2528
NP_001167588                                                           17    2528
XP_005254315                                                           17    2528
XP_005254314                                                           17    2528
XP_006720509                                                           17    2528
XP_005254313                                                           17    2528
XP_005254312                                                           17    2528
NP_065759                                                              17    4312
NP_001128243                                                           17    4312
NP_003483                                                              16    5631
NP_001073936                                                           16    7355
NP_036260                                                              16    7355
NP_006368                                                              16    7355
NP_001073890                                                           16    7355
XP_006722755                                                           16    7355
XP_006716779                                                           16    7355
XP_006710516                                                           16    7355
NP_001186072                                                           15    9605
NP_006353                                                              15    9605
NP_005952                                                              15    9605
NP_775840                                                              15    9605
XP_006718483                                                           15    9605
XP_006718482                                                           15    9605
XP_006718481                                                           15    9605
XP_006715979                                                           15    9605
XP_005250306                                                           15    9605

>NP_036462
          Length = 2073

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TTSSTYISA 9
           TT+STYISA
Sbjct: 414 TTTSTYISA 422



>NP_001243397
          Length = 1890

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TTSSTYISA 9
           TT+STYISA
Sbjct: 414 TTTSTYISA 422



>XP_005269721
          Length = 2073

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TTSSTYISA 9
           TT+STYISA
Sbjct: 414 TTTSTYISA 422



>NP_056078
          Length = 3036

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    TSSTYIS 8
            TSSTYIS
Sbjct: 1764 TSSTYIS 1770



>NP_689845
          Length = 976

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   TSSTYIS 8
           TSSTYIS
Sbjct: 805 TSSTYIS 811



>NP_001167587
          Length = 3037

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    TSSTYIS 8
            TSSTYIS
Sbjct: 1764 TSSTYIS 1770



>NP_001167588
          Length = 2400

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    TSSTYIS 8
            TSSTYIS
Sbjct: 1128 TSSTYIS 1134



>XP_005254315
          Length = 2576

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    TSSTYIS 8
            TSSTYIS
Sbjct: 1764 TSSTYIS 1770



>XP_005254314
          Length = 2605

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    TSSTYIS 8
            TSSTYIS
Sbjct: 1764 TSSTYIS 1770



>XP_006720509
          Length = 2646

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    TSSTYIS 8
            TSSTYIS
Sbjct: 1764 TSSTYIS 1770



>XP_005254313
          Length = 3057

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    TSSTYIS 8
            TSSTYIS
Sbjct: 1764 TSSTYIS 1770



>XP_005254312
          Length = 3058

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    TSSTYIS 8
            TSSTYIS
Sbjct: 1764 TSSTYIS 1770



>NP_065759
          Length = 1116

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTSSTYISA 9
           TTS+ YIS+
Sbjct: 441 TTSAVYISS 449



>NP_001128243
          Length = 1139

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTSSTYISA 9
           TTS+ YIS+
Sbjct: 464 TTSAVYISS 472



>NP_003483
          Length = 261

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TTSSTYIS 8
           TTS+TY++
Sbjct: 188 TTSATYLA 195



>NP_001073936
          Length = 1848

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   TTSSTYI 7
           TTS TY+
Sbjct: 383 TTSETYV 389



>NP_036260
          Length = 919

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  TTSSTYI 7
          TT+STY+
Sbjct: 57 TTASTYL 63



>NP_006368
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTSSTYISA 9
           TT+ST +SA
Sbjct: 835 TTASTNVSA 843



>NP_001073890
          Length = 1703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTSSTYISA 9
           TT+ST +SA
Sbjct: 911 TTASTNVSA 919



>XP_006722755
          Length = 1722

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TTSSTYISA 9
           TT+ST +SA
Sbjct: 911 TTASTNVSA 919



>XP_006716779
          Length = 2399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    TTSSTYISA 9
            TT+ST +SA
Sbjct: 1643 TTASTNVSA 1651



>XP_006710516
          Length = 514

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  TTSSTYI 7
          TT+STY+
Sbjct: 57 TTASTYL 63



>NP_001186072
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SSTYIS 8
           SSTYIS
Sbjct: 216 SSTYIS 221



>NP_006353
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   STYISA 9
           STYISA
Sbjct: 335 STYISA 340



>NP_005952
          Length = 2439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    TSSTYISA 9
            TSS+++SA
Sbjct: 2161 TSSSFVSA 2168



>NP_775840
          Length = 1347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TTSSTYIS 8
            TTSS Y++
Sbjct: 1008 TTSSNYLA 1015



>XP_006718483
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   STYISA 9
           STYISA
Sbjct: 335 STYISA 340



>XP_006718482
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   STYISA 9
           STYISA
Sbjct: 335 STYISA 340



>XP_006718481
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   STYISA 9
           STYISA
Sbjct: 335 STYISA 340



>XP_006715979
          Length = 1136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TTSSTYIS 8
           TTSS Y++
Sbjct: 797 TTSSNYLA 804



>XP_005250306
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TTSSTYIS 8
           TTSS Y++
Sbjct: 831 TTSSNYLA 838



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.290   0.0947    0.217 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 333,209
Number of extensions: 396
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)