Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001193949                                                           16    7355
XP_006724319                                                           16    7355
XP_006724318                                                           16    7355
XP_006724317                                                           16    7355
NP_001164197                                                           16    7355
NP_056194                                                              15    9605
NP_001152963                                                           15    9605
NP_001135876                                                           15    9605
NP_001135875                                                           15    9605
NP_006007                                                              15    9605
XP_005250309                                                           15    9605
XP_005250308                                                           15    9605
NP_001135873                                                           15    9605
>NP_001193949
          Length = 397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RTVTRSL 9
           RTVTR+L
Sbjct: 173 RTVTRAL 179
>XP_006724319
          Length = 452

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RTVTRSL 9
           RTVTR+L
Sbjct: 173 RTVTRAL 179
>XP_006724318
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RTVTRSL 9
           RTVTR+L
Sbjct: 173 RTVTRAL 179
>XP_006724317
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RTVTRSL 9
           RTVTR+L
Sbjct: 173 RTVTRAL 179
>NP_001164197
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TSRTVTRS 8
          TSR VTR+
Sbjct: 47 TSRNVTRA 54
>NP_056194
          Length = 125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  SRTVTR 7
          SRTVTR
Sbjct: 61 SRTVTR 66
>NP_001152963
          Length = 98

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  SRTVTR 7
          SRTVTR
Sbjct: 61 SRTVTR 66
>NP_001135876
          Length = 157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TSRTVTRS 8
           TS+TVT S
Sbjct: 135 TSKTVTTS 142
>NP_001135875
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TSRTVTRS 8
           TS+TVT S
Sbjct: 135 TSKTVTTS 142
>NP_006007
          Length = 197

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TSRTVTRS 8
           TS+TVT S
Sbjct: 135 TSKTVTTS 142
>XP_005250309
          Length = 105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  SRTVTR 7
          SRTVTR
Sbjct: 61 SRTVTR 66
>XP_005250308
          Length = 105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  SRTVTR 7
          SRTVTR
Sbjct: 61 SRTVTR 66
>NP_001135873
          Length = 184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TSRTVTRS 8
           TS+TVT S
Sbjct: 122 TSKTVTTS 129
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.111    0.260 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 273,563
Number of extensions: 245
Number of successful extensions: 13
Number of sequences better than 10000.0: 13
Number of HSP's gapped: 13
Number of HSP's successfully gapped: 13
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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