Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

• Home Page
• Cancer-specific
• Epitope Search
• Data Retrieval
• Browse Gene
• Browse Tissue
• Sequence Similarity
• Partially Personalized
• Submit a Protein
• Vaccine Target
• Proteome Data
• NGS data
• BLAST & Predict
• Fully Personalized
• Proteins Pair
• Proteome Pair
• Advanced Tools
• Epitope Mapping
• Cross Reactivity
• Important Information
• Acknowledgement
• Algorithm
• Help
• Developers
• Contact

Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              20     509
NP_001263689                                                           20     509
NP_001119584                                                           20     509
NP_001119586                                                           20     509
NP_001263625                                                           20     509
NP_001119590                                                           20     509
NP_001263690                                                           20     509
NP_001119585                                                           20     509
NP_001263624                                                           20     509
NP_001119588                                                           20     509
NP_001119587                                                           20     509
NP_001119589                                                           20     509
NP_003310                                                              17    4312
NP_597676                                                              17    4312
NP_001243779                                                           17    4312
NP_596869                                                              17    4312
XP_005246888                                                           17    4312
XP_006712788                                                           17    4312
XP_006712787                                                           17    4312
XP_006712786                                                           17    4312
NP_001254479                                                           17    4312
NP_597681                                                              17    4312
NP_061982                                                              15    9605
NP_001008844                                                           15    9605
NP_004406                                                              15    9605
XP_005255488                                                           15    9605

>NP_000537
          Length = 393

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRVRAMTIY 9
           TRVRAM IY
Sbjct: 155 TRVRAMAIY 163



>NP_001263689
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRVRAMTIY 9
           TRVRAM IY
Sbjct: 116 TRVRAMAIY 124



>NP_001119584
          Length = 393

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRVRAMTIY 9
           TRVRAM IY
Sbjct: 155 TRVRAMAIY 163



>NP_001119586
          Length = 341

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRVRAMTIY 9
           TRVRAM IY
Sbjct: 155 TRVRAMAIY 163



>NP_001263625
          Length = 302

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRVRAMTIY 9
           TRVRAM IY
Sbjct: 116 TRVRAMAIY 124



>NP_001119590
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRVRAMTIY 9
           TRVRAM IY
Sbjct: 116 TRVRAMAIY 124



>NP_001263690
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRVRAMTIY 9
           TRVRAM IY
Sbjct: 116 TRVRAMAIY 124



>NP_001119585
          Length = 346

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRVRAMTIY 9
           TRVRAM IY
Sbjct: 155 TRVRAMAIY 163



>NP_001263624
          Length = 307

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TRVRAMTIY 9
           TRVRAM IY
Sbjct: 116 TRVRAMAIY 124



>NP_001119588
          Length = 209

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TRVRAMTIY 9
          TRVRAM IY
Sbjct: 23 TRVRAMAIY 31



>NP_001119587
          Length = 261

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TRVRAMTIY 9
          TRVRAM IY
Sbjct: 23 TRVRAMAIY 31



>NP_001119589
          Length = 214

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  TRVRAMTIY 9
          TRVRAM IY
Sbjct: 23 TRVRAMAIY 31



>NP_003310
          Length = 26926

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     TRVRAMTIY 9
             T+ R+MT+Y
Sbjct: 26068 TKPRSMTVY 26076



>NP_597676
          Length = 27051

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     TRVRAMTIY 9
             T+ R+MT+Y
Sbjct: 26193 TKPRSMTVY 26201



>NP_001243779
          Length = 34350

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     TRVRAMTIY 9
             T+ R+MT+Y
Sbjct: 33492 TKPRSMTVY 33500



>NP_596869
          Length = 33423

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     TRVRAMTIY 9
             T+ R+MT+Y
Sbjct: 32565 TKPRSMTVY 32573



>XP_005246888
          Length = 22663

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     TRVRAMTIY 9
             T+ R+MT+Y
Sbjct: 21805 TKPRSMTVY 21813



>XP_006712788
          Length = 24022

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     TRVRAMTIY 9
             T+ R+MT+Y
Sbjct: 23164 TKPRSMTVY 23172



>XP_006712787
          Length = 33978

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     TRVRAMTIY 9
             T+ R+MT+Y
Sbjct: 33120 TKPRSMTVY 33128



>XP_006712786
          Length = 35484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     TRVRAMTIY 9
             T+ R+MT+Y
Sbjct: 34626 TKPRSMTVY 34634



>NP_001254479
          Length = 35991

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     TRVRAMTIY 9
             T+ R+MT+Y
Sbjct: 35133 TKPRSMTVY 35141



>NP_597681
          Length = 27118

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     TRVRAMTIY 9
             T+ R+MT+Y
Sbjct: 26260 TKPRSMTVY 26268



>NP_061982
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VRAMTIY 9
           +RA+T+Y
Sbjct: 209 IRAVTVY 215



>NP_001008844
          Length = 2272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVRAMTI 8
           ++RAMTI
Sbjct: 559 KIRAMTI 565



>NP_004406
          Length = 2871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVRAMTI 8
           ++RAMTI
Sbjct: 559 KIRAMTI 565



>XP_005255488
          Length = 303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VRAMTIY 9
           +RA+T+Y
Sbjct: 209 IRAVTVY 215



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.136    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 239,782
Number of extensions: 277
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)