Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_060738                                                              16    5631
XP_006714719                                                           16    5631
XP_005248609                                                           16    5631
XP_005248608                                                           16    5631
NP_036222                                                              16    7355
NP_001269723                                                           16    7355
NP_055705                                                              16    7355
NP_001269722                                                           16    7355
NP_001035924                                                           16    7355
NP_878913                                                              16    7355
XP_006713549                                                           16    7355
XP_006710603                                                           16    7355
XP_006710602                                                           16    7355
XP_006710601                                                           16    7355
XP_006710600                                                           16    7355
XP_005270757                                                           16    7355
XP_006710599                                                           16    7355
XP_006710598                                                           16    7355
XP_006710597                                                           16    7355
XP_006710596                                                           16    7355
XP_006710595                                                           16    7355
XP_006710594                                                           16    7355
XP_006710593                                                           16    7355
XP_006710592                                                           16    7355
XP_006710591                                                           16    7355
XP_006710590                                                           16    7355
XP_006710589                                                           16    7355
XP_006710588                                                           16    7355
XP_006710587                                                           16    7355
XP_006710586                                                           16    7355
XP_006710585                                                           16    7355
XP_005270755                                                           16    7355
XP_006710584                                                           16    7355
XP_005270754                                                           16    7355
XP_005270753                                                           16    7355
XP_006710583                                                           16    7355
XP_005270752                                                           16    7355
XP_006710582                                                           16    7355
XP_005270751                                                           16    7355
NP_899236                                                              15    9605
NP_001714                                                              15    9605
NP_056363                                                              15    9605
NP_001138241                                                           15    9605
NP_001138242                                                           15    9605
NP_001640                                                              15    9605
XP_005274557                                                           15    9605
XP_006715232                                                           15    9605
XP_005249383                                                           15    9605
XP_005249382                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QRVTASVT 9
           QRVTASVT
Sbjct: 876 QRVTASVT 883
>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   QRVTASVT 9
           QRVTASVT
Sbjct: 671 QRVTASVT 678
>NP_060738
          Length = 459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TQRVTASVT 9
          TQ++TA +T
Sbjct: 84 TQKITAIIT 92
>XP_006714719
          Length = 286

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TQRVTASVT 9
          TQ++TA +T
Sbjct: 84 TQKITAIIT 92
>XP_005248609
          Length = 367

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TQRVTASVT 9
          TQ++TA +T
Sbjct: 84 TQKITAIIT 92
>XP_005248608
          Length = 401

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TQRVTASVT 9
          TQ++TA +T
Sbjct: 84 TQKITAIIT 92
>NP_036222
          Length = 5430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 204 TQKVTAGYT 212
>NP_001269723
          Length = 895

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TQRVTASVT 9
           T +VT+S+T
Sbjct: 864 TNKVTSSIT 872
>NP_055705
          Length = 893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TQRVTASVT 9
           T +VT+S+T
Sbjct: 864 TNKVTSSIT 872
>NP_001269722
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TQRVTASVT 9
           T +VT+S+T
Sbjct: 680 TNKVTSSIT 688
>NP_001035924
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TQRVTASVT 9
            T +VT+S+T
Sbjct: 1104 TNKVTSSIT 1112
>NP_878913
          Length = 1135

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    TQRVTASVT 9
            T +VT+S+T
Sbjct: 1104 TNKVTSSIT 1112
>XP_006713549
          Length = 893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TQRVTASVT 9
           T +VT+S+T
Sbjct: 864 TNKVTSSIT 872
>XP_006710603
          Length = 5324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 204 TQKVTAGYT 212
>XP_006710602
          Length = 7391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 204 TQKVTAGYT 212
>XP_006710601
          Length = 4720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_006710600
          Length = 5384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 204 TQKVTAGYT 212
>XP_005270757
          Length = 5460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_006710599
          Length = 5656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_006710598
          Length = 7553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 194 TQKVTAGYT 202
>XP_006710597
          Length = 7451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 204 TQKVTAGYT 212
>XP_006710596
          Length = 7512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 153 TQKVTAGYT 161
>XP_006710595
          Length = 7526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 167 TQKVTAGYT 175
>XP_006710594
          Length = 7528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 169 TQKVTAGYT 177
>XP_006710593
          Length = 7539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 180 TQKVTAGYT 188
>XP_006710592
          Length = 7544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 185 TQKVTAGYT 193
>XP_006710591
          Length = 7558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 199 TQKVTAGYT 207
>XP_006710590
          Length = 7563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 204 TQKVTAGYT 212
>XP_006710589
          Length = 7595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 236 TQKVTAGYT 244
>XP_006710588
          Length = 7614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_006710587
          Length = 7645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_006710586
          Length = 7645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_006710585
          Length = 7657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_005270755
          Length = 7663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_006710584
          Length = 7686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_005270754
          Length = 7694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_005270753
          Length = 7700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_006710583
          Length = 7702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_005270752
          Length = 7717

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_006710582
          Length = 7720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>XP_005270751
          Length = 7723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           TQ+VTA  T
Sbjct: 364 TQKVTAGYT 372
>NP_899236
          Length = 5497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 544 TSRLTPSVT 552
>NP_001714
          Length = 2649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 218 TSRLTPSVT 226
>NP_056363
          Length = 5171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 218 TSRLTPSVT 226
>NP_001138241
          Length = 5675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 722 TSRLTPSVT 730
>NP_001138242
          Length = 5537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 584 TSRLTPSVT 592
>NP_001640
          Length = 1616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TQRVTASVT 9
           +QR+ AS+T
Sbjct: 562 SQRLAASIT 570
>XP_005274557
          Length = 1615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TQRVTASVT 9
           +QR+ AS+T
Sbjct: 562 SQRLAASIT 570
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 544 TSRLTPSVT 552
>XP_005249383
          Length = 3186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 755 TSRLTPSVT 763
>XP_005249382
          Length = 5732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 755 TSRLTPSVT 763
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 218 TSRLTPSVT 226
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 544 TSRLTPSVT 552
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 570 TSRLTPSVT 578
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 577 TSRLTPSVT 585
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 584 TSRLTPSVT 592
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 617 TSRLTPSVT 625
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 755 TSRLTPSVT 763
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 660 TSRLTPSVT 668
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 722 TSRLTPSVT 730
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 755 TSRLTPSVT 763
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 755 TSRLTPSVT 763
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 734 TSRLTPSVT 742
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 755 TSRLTPSVT 763
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TQRVTASVT 9
           T R+T SVT
Sbjct: 755 TSRLTPSVT 763
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.104    0.239 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 229,701
Number of extensions: 277
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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