Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_001707                                                              17    3301
NP_116743                                                              17    3301
NP_001001922                                                           17    4312
NP_001495                                                              16    5631
NP_001136269                                                           16    5631
NP_001035888                                                           16    5631
NP_004198                                                              16    5631
NP_001193880                                                           16    5631
NP_001193881                                                           16    5631
NP_001035887                                                           16    5631
NP_001193879                                                           16    5631
NP_757385                                                              16    5631
NP_115807                                                              16    5631
NP_005848                                                              16    5631
XP_005262314                                                           16    5631
XP_005262313                                                           16    5631
XP_006718776                                                           16    5631
XP_006718775                                                           16    5631
NP_079022                                                              16    7355
NP_071442                                                              16    7355
NP_001287                                                              16    7355
NP_640338                                                              16    7355
XP_006713570                                                           16    7355
NP_110392                                                              16    7355
NP_003605                                                              16    7355
NP_001186112                                                           15    9605
NP_001186108                                                           15    9605
NP_001186113                                                           15    9605
NP_001001486                                                           15    9605
NP_055197                                                              15    9605
NP_001186110                                                           15    9605
NP_619648                                                              15    9605
NP_001186109                                                           15    9605
NP_001001487                                                           15    9605
NP_001186111                                                           15    9605
NP_003974                                                              15    9605
NP_001070253                                                           15    9605
NP_056042                                                              15    9605
NP_055736                                                              15    9605
NP_598368                                                              15    9605
NP_001244960                                                           15    9605
NP_001180438                                                           15    9605
NP_001172014                                                           15    9605
NP_001008701                                                           15    9605
NP_060205                                                              15    9605
NP_001667                                                              15    9605
XP_006724047                                                           15    9605
XP_006724044                                                           15    9605
XP_005259876                                                           15    9605
XP_006722752                                                           15    9605
XP_005259875                                                           15    9605
XP_006722751                                                           15    9605
XP_005247415                                                           15    9605
XP_005247414                                                           15    9605
XP_005247413                                                           15    9605
XP_006713648                                                           15    9605
XP_005247412                                                           15    9605
XP_005247411                                                           15    9605
XP_005264473                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TMSLIFLLG 9
            TMSL FLLG
Sbjct: 2942 TMSLTFLLG 2950
>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TMSLIFLLG 9
            TMSL FLLG
Sbjct: 2737 TMSLTFLLG 2745
>NP_001707
          Length = 372

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLIFLLG 9
          SLIFLLG
Sbjct: 59 SLIFLLG 65
>NP_116743
          Length = 327

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  SLIFLLG 9
          SLIFLLG
Sbjct: 14 SLIFLLG 20
>NP_001001922
          Length = 324

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TMSLIFLLG 9
          TM +IFL+G
Sbjct: 41 TMYIIFLVG 49
>NP_001495
          Length = 368

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SLIFLLG 9
          SL+FLLG
Sbjct: 61 SLLFLLG 67
>NP_001136269
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SLIFLLG 9
           SL+FLLG
Sbjct: 108 SLLFLLG 114
>NP_001035888
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TMSLIFLLG 9
           T SLI LLG
Sbjct: 397 TSSLILLLG 405
>NP_004198
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TMSLIFLLG 9
           T SLI LLG
Sbjct: 397 TSSLILLLG 405
>NP_001193880
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TMSLIFLLG 9
           T SLI LLG
Sbjct: 397 TSSLILLLG 405
>NP_001193881
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TMSLIFLLG 9
           T SLI LLG
Sbjct: 397 TSSLILLLG 405
>NP_001035887
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TMSLIFLLG 9
           T SLI LLG
Sbjct: 397 TSSLILLLG 405
>NP_001193879
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TMSLIFLLG 9
           T SLI LLG
Sbjct: 397 TSSLILLLG 405
>NP_757385
          Length = 617

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSLIFLLG 9
           +SL+FLLG
Sbjct: 142 VSLMFLLG 149
>NP_115807
          Length = 616

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSLIFLLG 9
           +SL+FLLG
Sbjct: 142 VSLMFLLG 149
>NP_005848
          Length = 475

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TMSLIFLL 8
           T SL+FLL
Sbjct: 121 TQSLVFLL 128
>XP_005262314
          Length = 278

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SLIFLLG 9
          SL+FLLG
Sbjct: 71 SLLFLLG 77
>XP_005262313
          Length = 378

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SLIFLLG 9
          SL+FLLG
Sbjct: 71 SLLFLLG 77
>XP_006718776
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSLIFLLG 9
           +SL+FLLG
Sbjct: 142 VSLMFLLG 149
>XP_006718775
          Length = 670

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   MSLIFLLG 9
           +SL+FLLG
Sbjct: 142 VSLMFLLG 149
>NP_079022
          Length = 724

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  MSLIFLLG 9
          + LIFLLG
Sbjct: 27 LCLIFLLG 34
>NP_071442
          Length = 690

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   MSLIFLLG 9
           ++L+FLLG
Sbjct: 621 LALLFLLG 628
>NP_001287
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SLIFLLG 9
          SLIF+LG
Sbjct: 54 SLIFVLG 60
>NP_640338
          Length = 360

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TMSLIFLLG 9
          TM+L+ LLG
Sbjct: 5  TMTLLSLLG 13
>XP_006713570
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TMSLIFLLG 9
          TM+L+ LLG
Sbjct: 5  TMTLLSLLG 13
>NP_110392
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 153 LKLVFLLG 160
>NP_003605
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SLIFLLG 9
          +LIFLLG
Sbjct: 25 ALIFLLG 31
>NP_001186112
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 860 LDLLFLLG 867
>NP_001186108
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 876 LDLLFLLG 883
>NP_001186113
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 860 LDLLFLLG 867
>NP_001001486
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 876 LDLLFLLG 883
>NP_055197
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 876 LDLLFLLG 883
>NP_001186110
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 910 LDLLFLLG 917
>NP_619648
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + LIFL+G
Sbjct: 408 LGLIFLMG 415
>NP_001186109
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 910 LDLLFLLG 917
>NP_001001487
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 876 LDLLFLLG 883
>NP_001186111
          Length = 944

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 871 LDLLFLLG 878
>NP_003974
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TMSLIFLL 8
           TM+LI+L+
Sbjct: 375 TMALIYLI 382
>NP_001070253
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   TMSLIFLL 8
           TM+LI+L+
Sbjct: 375 TMALIYLI 382
>NP_056042
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TMSLIFLL 8
          T+S +FLL
Sbjct: 3  TLSFVFLL 10
>NP_055736
          Length = 1469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    MSLIFLLG 9
            ++L+FLLG
Sbjct: 1049 IALLFLLG 1056
>NP_598368
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TMSLIFLL 8
          T+S +FLL
Sbjct: 3  TLSFVFLL 10
>NP_001244960
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 157 LKLLFLLG 164
>NP_001180438
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LIFLLG 9
          LIFLLG
Sbjct: 42 LIFLLG 47
>NP_001172014
          Length = 1045

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLIFLLG 9
           S+IFL+G
Sbjct: 341 SIIFLIG 347
>NP_001008701
          Length = 1474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    MSLIFLLG 9
            ++L+FLLG
Sbjct: 1054 IALLFLLG 1061
>NP_060205
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LIFLLG 9
          LIFLLG
Sbjct: 92 LIFLLG 97
>NP_001667
          Length = 1039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SLIFLLG 9
           S+IFL+G
Sbjct: 335 SIIFLIG 341
>XP_006724047
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TMSLIFLL 8
          T+S +FLL
Sbjct: 3  TLSFVFLL 10
>XP_006724044
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TMSLIFLL 8
          T+S +FLL
Sbjct: 3  TLSFVFLL 10
>XP_005259876
          Length = 1498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    MSLIFLLG 9
            ++L+FLLG
Sbjct: 1054 IALLFLLG 1061
>XP_006722752
          Length = 1462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    MSLIFLLG 9
            ++L+FLLG
Sbjct: 1018 IALLFLLG 1025
>XP_005259875
          Length = 1493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    MSLIFLLG 9
            ++L+FLLG
Sbjct: 1049 IALLFLLG 1056
>XP_006722751
          Length = 1498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    MSLIFLLG 9
            ++L+FLLG
Sbjct: 1054 IALLFLLG 1061
>XP_005247415
          Length = 933

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 860 LDLLFLLG 867
>XP_005247414
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 876 LDLLFLLG 883
>XP_005247413
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 876 LDLLFLLG 883
>XP_006713648
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 876 LDLLFLLG 883
>XP_005247412
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 876 LDLLFLLG 883
>XP_005247411
          Length = 983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MSLIFLLG 9
           + L+FLLG
Sbjct: 910 LDLLFLLG 917
>XP_005264473
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LIFLLG 9
          LIFLLG
Sbjct: 92 LIFLLG 97
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.156    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 348,637
Number of extensions: 584
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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