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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     299
XP_005262424                                                           20     299
NP_001010872                                                           17    3301
XP_006715085                                                           17    3301
NP_787036                                                              17    4312
NP_001257620                                                           17    4312
XP_005270830                                                           17    4312
NP_001035799                                                           17    4312
NP_001265662                                                           16    7355
NP_473455                                                              16    7355
NP_687034                                                              16    7355
XP_005276374                                                           16    7355
XP_005273748                                                           16    7355
XP_005276074                                                           16    7355
NP_036313                                                              15    9605
NP_055196                                                              15    9605
NP_001035197                                                           15    9605
NP_683692                                                              15    9605
NP_001037853                                                           15    9605
NP_001037852                                                           15    9605
NP_077317                                                              15    9605
XP_005259899                                                           15    9605
XP_005259898                                                           15    9605
XP_005267591                                                           15    9605
XP_005267590                                                           15    9605
XP_005267589                                                           15    9605
XP_005267588                                                           15    9605
XP_006720179                                                           15    9605
XP_005248208                                                           15    9605
XP_005248207                                                           15    9605
XP_006714021                                                           15    9605

>NP_722576
          Length = 3080

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TKSSKTMH 8
            TKSSKTMH
Sbjct: 1537 TKSSKTMH 1544



>XP_005262424
          Length = 2875

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    TKSSKTMH 8
            TKSSKTMH
Sbjct: 1332 TKSSKTMH 1339



>NP_001010872
          Length = 1011

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KSSKTMH 8
           KSSK+MH
Sbjct: 705 KSSKSMH 711



>XP_006715085
          Length = 1011

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KSSKTMH 8
           KSSK+MH
Sbjct: 705 KSSKSMH 711



>NP_787036
          Length = 532

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TKSSKTMH 8
           T+SSKT H
Sbjct: 451 TESSKTAH 458



>NP_001257620
          Length = 585

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TKSSKTMH 8
           T+SSKT H
Sbjct: 504 TESSKTAH 511



>XP_005270830
          Length = 236

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SSKTMH 8
           SSKTMH
Sbjct: 101 SSKTMH 106



>NP_001035799
          Length = 272

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SSKTMH 8
           SSKTMH
Sbjct: 101 SSKTMH 106



>NP_001265662
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KSSKTMHA 9
           K S+T+HA
Sbjct: 605 KQSRTVHA 612



>NP_473455
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KSSKTMHA 9
           K S+T+HA
Sbjct: 668 KQSRTVHA 675



>NP_687034
          Length = 553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KSSKTMHA 9
           K S+T+HA
Sbjct: 490 KQSRTVHA 497



>XP_005276374
          Length = 264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SSKTMHA 9
          S+KT+HA
Sbjct: 27 SAKTLHA 33



>XP_005273748
          Length = 264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SSKTMHA 9
          S+KT+HA
Sbjct: 27 SAKTLHA 33



>XP_005276074
          Length = 264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SSKTMHA 9
          S+KT+HA
Sbjct: 27 SAKTLHA 33



>NP_036313
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SSKTMHA 9
           S+KT+HA
Sbjct: 339 SNKTIHA 345



>NP_055196
          Length = 1429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKSSKTMHA 9
           TKS++T H+
Sbjct: 618 TKSTETEHS 626



>NP_001035197
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKSSKTMHA 9
           TKS++T H+
Sbjct: 618 TKSTETEHS 626



>NP_683692
          Length = 3051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TKSSKT 6
           TKSSKT
Sbjct: 526 TKSSKT 531



>NP_001037853
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TKSSKTMH 8
           TKSS T H
Sbjct: 156 TKSSLTRH 163



>NP_001037852
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TKSSKTMH 8
           TKSS T H
Sbjct: 163 TKSSLTRH 170



>NP_077317
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TKSSKTMH 8
           TKSS T H
Sbjct: 163 TKSSLTRH 170



>XP_005259899
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SSKTMHA 9
           S+KT+HA
Sbjct: 367 SNKTIHA 373



>XP_005259898
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SSKTMHA 9
           S+KT+HA
Sbjct: 368 SNKTIHA 374



>XP_005267591
          Length = 1275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKSSKTMHA 9
           TKS++T H+
Sbjct: 618 TKSTETEHS 626



>XP_005267590
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKSSKTMHA 9
           TKS++T H+
Sbjct: 618 TKSTETEHS 626



>XP_005267589
          Length = 1418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKSSKTMHA 9
           TKS++T H+
Sbjct: 618 TKSTETEHS 626



>XP_005267588
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKSSKTMHA 9
           TKS++T H+
Sbjct: 618 TKSTETEHS 626



>XP_006720179
          Length = 1453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TKSSKTMHA 9
           TKS++T H+
Sbjct: 618 TKSTETEHS 626



>XP_005248208
          Length = 3097

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TKSSKT 6
           TKSSKT
Sbjct: 526 TKSSKT 531



>XP_005248207
          Length = 3098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TKSSKT 6
           TKSSKT
Sbjct: 526 TKSSKT 531



>XP_006714021
          Length = 3112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TKSSKT 6
           TKSSKT
Sbjct: 526 TKSSKT 531



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294   0.0931    0.229 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 336,557
Number of extensions: 434
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)