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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001273052                                                           17    2528
NP_001273054                                                           17    2528
NP_005826                                                              17    2528
XP_006715015                                                           17    2528
XP_006715014                                                           17    2528
XP_006715013                                                           17    2528
XP_006715012                                                           17    2528
XP_005248841                                                           17    2528
NP_055789                                                              17    3301
XP_005252487                                                           17    3301
XP_005252486                                                           17    3301
XP_005252485                                                           17    3301
XP_005252484                                                           17    3301
XP_005252483                                                           17    3301
NP_001229602                                                           17    4312
NP_149985                                                              17    4312
NP_006612                                                              17    4312
NP_001229604                                                           17    4312
NP_001229603                                                           17    4312
NP_001229605                                                           17    4312
NP_001136069                                                           17    4312
NP_063939                                                              17    4312
XP_006718488                                                           17    4312
NP_006822                                                              17    4312
NP_071913                                                              16    7355
NP_056261                                                              16    7355
NP_055463                                                              16    7355
XP_005247976                                                           16    7355
XP_005247975                                                           16    7355
XP_005247974                                                           16    7355
XP_005247973                                                           16    7355
XP_005247972                                                           16    7355
XP_005247971                                                           16    7355
XP_006711822                                                           16    7355
XP_006711821                                                           16    7355
NP_057427                                                              15    9605
NP_958784                                                              15    9605
XP_005251036                                                           15    9605
XP_005250000                                                           15    9605

>NP_001273052
          Length = 478

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TKAAVFSW 8
          TKA+V+ W
Sbjct: 79 TKASVYQW 86



>NP_001273054
          Length = 398

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TKAAVFSW 8
          TKA+V+ W
Sbjct: 79 TKASVYQW 86



>NP_005826
          Length = 436

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TKAAVFSW 8
          TKA+V+ W
Sbjct: 79 TKASVYQW 86



>XP_006715015
          Length = 356

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TKAAVFSW 8
          TKA+V+ W
Sbjct: 79 TKASVYQW 86



>XP_006715014
          Length = 398

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TKAAVFSW 8
          TKA+V+ W
Sbjct: 79 TKASVYQW 86



>XP_006715013
          Length = 455

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TKAAVFSW 8
          TKA+V+ W
Sbjct: 56 TKASVYQW 63



>XP_006715012
          Length = 478

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TKAAVFSW 8
          TKA+V+ W
Sbjct: 79 TKASVYQW 86



>XP_005248841
          Length = 478

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TKAAVFSW 8
          TKA+V+ W
Sbjct: 79 TKASVYQW 86



>NP_055789
          Length = 1556

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TKAAVFSW 8
            T+ AVF+W
Sbjct: 1471 TECAVFTW 1478



>XP_005252487
          Length = 919

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TKAAVFSW 8
           T+ AVF+W
Sbjct: 834 TECAVFTW 841



>XP_005252486
          Length = 1407

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TKAAVFSW 8
            T+ AVF+W
Sbjct: 1322 TECAVFTW 1329



>XP_005252485
          Length = 1622

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TKAAVFSW 8
            T+ AVF+W
Sbjct: 1537 TECAVFTW 1544



>XP_005252484
          Length = 1566

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TKAAVFSW 8
            T+ AVF+W
Sbjct: 1481 TECAVFTW 1488



>XP_005252483
          Length = 1612

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TKAAVFSW 8
            T+ AVF+W
Sbjct: 1527 TECAVFTW 1534



>NP_001229602
          Length = 483

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AVFSWK 9
           AVF+WK
Sbjct: 149 AVFAWK 154



>NP_149985
          Length = 549

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   KAAVFSW 8
           K+A+F+W
Sbjct: 377 KSAIFNW 383



>NP_006612
          Length = 530

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AVFSWK 9
           AVF+WK
Sbjct: 196 AVFAWK 201



>NP_001229604
          Length = 483

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AVFSWK 9
           AVF+WK
Sbjct: 149 AVFAWK 154



>NP_001229603
          Length = 483

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AVFSWK 9
           AVF+WK
Sbjct: 149 AVFAWK 154



>NP_001229605
          Length = 483

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AVFSWK 9
           AVF+WK
Sbjct: 149 AVFAWK 154



>NP_001136069
          Length = 361

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  KAAVFSW 8
          K AVF+W
Sbjct: 62 KVAVFTW 68



>NP_063939
          Length = 486

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TKAAVFSWK 9
           T AA+F W+
Sbjct: 188 TTAALFRWR 196



>XP_006718488
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  KAAVFSW 8
          K AVF+W
Sbjct: 62 KVAVFTW 68



>NP_006822
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  KAAVFSW 8
          K AVF+W
Sbjct: 62 KVAVFTW 68



>NP_071913
          Length = 562

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 4   AVFSW 8
           AVFSW
Sbjct: 418 AVFSW 422



>NP_056261
          Length = 2275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   TKAAVFSWK 9
           T  +VF+W+
Sbjct: 387 TSVSVFTWQ 395



>NP_055463
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KAAVFSW 8
           KAAV SW
Sbjct: 906 KAAVDSW 912



>XP_005247976
          Length = 1002

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KAAVFSW 8
           KAAV SW
Sbjct: 700 KAAVDSW 706



>XP_005247975
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KAAVFSW 8
           KAAV SW
Sbjct: 906 KAAVDSW 912



>XP_005247974
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KAAVFSW 8
           KAAV SW
Sbjct: 906 KAAVDSW 912



>XP_005247973
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KAAVFSW 8
           KAAV SW
Sbjct: 906 KAAVDSW 912



>XP_005247972
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KAAVFSW 8
           KAAV SW
Sbjct: 906 KAAVDSW 912



>XP_005247971
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KAAVFSW 8
           KAAV SW
Sbjct: 906 KAAVDSW 912



>XP_006711822
          Length = 2266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   TKAAVFSWK 9
           T  +VF+W+
Sbjct: 378 TSVSVFTWQ 386



>XP_006711821
          Length = 2301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   TKAAVFSWK 9
           T  +VF+W+
Sbjct: 413 TSVSVFTWQ 421



>NP_057427
          Length = 3114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   AAVFSWK 9
           ++VFSW+
Sbjct: 214 SSVFSWQ 220



>NP_958784
          Length = 4547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  TKAAVFSWK 9
          T AAV+ W+
Sbjct: 19 TLAAVWHWR 27



>XP_005251036
          Length = 4552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  TKAAVFSWK 9
          T AAV+ W+
Sbjct: 19 TLAAVWHWR 27



>XP_005250000
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 4  AVFSW 8
          A+FSW
Sbjct: 15 AIFSW 19



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.117    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 517,346
Number of extensions: 708
Number of successful extensions: 39
Number of sequences better than 10000.0: 39
Number of HSP's gapped: 39
Number of HSP's successfully gapped: 39
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)