Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           20     299
NP_055903                                                              20     299
NP_055309                                                              17    2528
XP_006721103                                                           17    2528
XP_005255314                                                           17    2528
XP_006721102                                                           17    2528
XP_005255313                                                           17    2528
XP_005255312                                                           17    2528
XP_006721101                                                           17    2528
XP_005255311                                                           17    2528
XP_005255310                                                           17    2528
NP_660305                                                              17    4312
NP_828847                                                              17    4312
NP_563615                                                              17    4312
XP_006713041                                                           17    4312
NP_004509                                                              16    5631
NP_742106                                                              16    5631
NP_742105                                                              16    5631
NP_742104                                                              16    5631
NP_742107                                                              16    5631
NP_114431                                                              16    5631
XP_006723855                                                           16    5631
XP_006723854                                                           16    5631
XP_006723853                                                           16    5631
XP_006723852                                                           16    5631
XP_006723851                                                           16    5631
XP_006723850                                                           16    5631
XP_005272168                                                           16    5631
XP_005272166                                                           16    5631
XP_005272164                                                           16    5631
XP_005272163                                                           16    5631
XP_005272162                                                           16    5631
XP_005272160                                                           16    5631
XP_006714780                                                           16    5631
NP_001180270                                                           16    7355
NP_689945                                                              16    7355
NP_001161707                                                           16    7355
XP_006715076                                                           16    7355
XP_005248958                                                           16    7355
NP_036421                                                              15    9605
NP_987096                                                              15    9605
NP_036284                                                              15    9605
NP_001014440                                                           15    9605
NP_036205                                                              15    9605
XP_006724480                                                           15    9605
XP_005261978                                                           15    9605
XP_006724479                                                           15    9605
XP_005261975                                                           15    9605
XP_006724478                                                           15    9605
XP_005260231                                                           15    9605
XP_005260230                                                           15    9605
XP_006710605                                                           15    9605
NP_857597                                                              15    9605
NP_001025052                                                           15    9605
>NP_001155973
          Length = 1833

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           T+LSRTDLD
Sbjct: 606 TLLSRTDLD 614
>NP_055903
          Length = 1723

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           T+LSRTDLD
Sbjct: 606 TLLSRTDLD 614
>NP_055309
          Length = 1962

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           +I++RTDLD
Sbjct: 706 SIVNRTDLD 714
>XP_006721103
          Length = 1597

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           +I++RTDLD
Sbjct: 674 SIVNRTDLD 682
>XP_005255314
          Length = 1709

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           +I++RTDLD
Sbjct: 453 SIVNRTDLD 461
>XP_006721102
          Length = 1820

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           +I++RTDLD
Sbjct: 564 SIVNRTDLD 572
>XP_005255313
          Length = 1822

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           +I++RTDLD
Sbjct: 674 SIVNRTDLD 682
>XP_005255312
          Length = 1871

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           +I++RTDLD
Sbjct: 674 SIVNRTDLD 682
>XP_006721101
          Length = 1907

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           +I++RTDLD
Sbjct: 674 SIVNRTDLD 682
>XP_005255311
          Length = 1913

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           +I++RTDLD
Sbjct: 706 SIVNRTDLD 714
>XP_005255310
          Length = 1919

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   TILSRTDLD 9
           +I++RTDLD
Sbjct: 674 SIVNRTDLD 682
>NP_660305
          Length = 523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TILSRTDLD 9
           T+LSR D D
Sbjct: 286 TVLSRADSD 294
>NP_828847
          Length = 509

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILSRTD 7
           T+LSRTD
Sbjct: 101 TLLSRTD 107
>NP_563615
          Length = 775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TILSRTD 7
           T+LSRTD
Sbjct: 717 TLLSRTD 723
>XP_006713041
          Length = 396

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TILSRTDLD 9
           T+LSR D D
Sbjct: 159 TVLSRADSD 167
>NP_004509
          Length = 844

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>NP_742106
          Length = 841

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>NP_742105
          Length = 872

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>NP_742104
          Length = 854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>NP_742107
          Length = 393

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>NP_114431
          Length = 416

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILSRTDLD 9
          +LSR DLD
Sbjct: 37 LLSRIDLD 44
>XP_006723855
          Length = 856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>XP_006723854
          Length = 858

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>XP_006723853
          Length = 868

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>XP_006723852
          Length = 876

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>XP_006723851
          Length = 885

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>XP_006723850
          Length = 886

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           T LSRTDL
Sbjct: 349 TNLSRTDL 356
>XP_005272168
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILSRTDLD 9
          +LSR DLD
Sbjct: 37 LLSRIDLD 44
>XP_005272166
          Length = 325

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILSRTDLD 9
          +LSR DLD
Sbjct: 37 LLSRIDLD 44
>XP_005272164
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILSRTDLD 9
          +LSR DLD
Sbjct: 37 LLSRIDLD 44
>XP_005272163
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILSRTDLD 9
          +LSR DLD
Sbjct: 37 LLSRIDLD 44
>XP_005272162
          Length = 352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILSRTDLD 9
          +LSR DLD
Sbjct: 37 LLSRIDLD 44
>XP_005272160
          Length = 388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILSRTDLD 9
          +LSR DLD
Sbjct: 37 LLSRIDLD 44
>XP_006714780
          Length = 416

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILSRTDLD 9
          +LSR DLD
Sbjct: 37 LLSRIDLD 44
>NP_001180270
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILSRTDLD 9
           T+L + DLD
Sbjct: 185 TLLEKADLD 193
>NP_689945
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILSRTDLD 9
           T+L + DLD
Sbjct: 200 TLLEKADLD 208
>NP_001161707
          Length = 2139

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILSRTDLD 9
           +LS TD+D
Sbjct: 566 VLSATDID 573
>XP_006715076
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  TILSRTDLD 9
          T+L + DLD
Sbjct: 85 TLLEKADLD 93
>XP_005248958
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TILSRTDLD 9
           T+L + DLD
Sbjct: 200 TLLEKADLD 208
>NP_036421
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TILSRTDLD 9
           T++SR DL+
Sbjct: 230 TLISRDDLN 238
>NP_987096
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TILSRTDLD 9
           T++SR DL+
Sbjct: 230 TLISRDDLN 238
>NP_036284
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILSRTD 7
           T+LSR+D
Sbjct: 326 TVLSRSD 332
>NP_001014440
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           TIL+RT L
Sbjct: 203 TILARTSL 210
>NP_036205
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TILSRTDLD 9
          TILS  D+D
Sbjct: 76 TILSMMDVD 84
>XP_006724480
          Length = 178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           TIL+RT L
Sbjct: 128 TILARTSL 135
>XP_005261978
          Length = 185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           TIL+RT L
Sbjct: 135 TILARTSL 142
>XP_006724479
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           TIL+RT L
Sbjct: 163 TILARTSL 170
>XP_005261975
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           TIL+RT L
Sbjct: 203 TILARTSL 210
>XP_006724478
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TILSRTDL 8
           TIL+RT L
Sbjct: 231 TILARTSL 238
>XP_005260231
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TILSRTDLD 9
           T++SR DL+
Sbjct: 230 TLISRDDLN 238
>XP_005260230
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TILSRTDLD 9
           T++SR DL+
Sbjct: 230 TLISRDDLN 238
>XP_006710605
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TILSRTD 7
           T+LSR+D
Sbjct: 326 TVLSRSD 332
>NP_857597
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    TILSRTDLD 9
            TIL+ TD D
Sbjct: 1015 TILADTDCD 1023
>NP_001025052
          Length = 185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILSRTDLD 9
           +LS +DLD
Sbjct: 147 VLSESDLD 154
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.136    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 410,603
Number of extensions: 517
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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