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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_009052                                                              19     869
NP_001243576                                                           19     869
NP_060469                                                              17    3301
NP_005684                                                              17    4312
NP_001238863                                                           17    4312
NP_001238864                                                           17    4312
NP_001123574                                                           17    4312
XP_006718179                                                           17    4312
XP_005252773                                                           17    4312
XP_005252772                                                           17    4312
XP_005252767                                                           17    4312
XP_005252766                                                           17    4312
XP_006718178                                                           17    4312
XP_006718177                                                           17    4312
XP_005252764                                                           17    4312
XP_005252763                                                           17    4312
XP_006718176                                                           17    4312
XP_006718175                                                           17    4312
XP_005252762                                                           17    4312
NP_573439                                                              16    7355
NP_573438                                                              16    7355
NP_001181930                                                           16    7355
NP_005695                                                              16    7355
XP_006710336                                                           16    7355
XP_006710335                                                           16    7355
XP_006710334                                                           16    7355
XP_006710333                                                           16    7355
XP_006710332                                                           16    7355
NP_056494                                                              15    9605

>NP_009052
          Length = 461

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TIEIMLLKT 9
           TIEIMLL+T
Sbjct: 308 TIEIMLLET 316



>NP_001243576
          Length = 364

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TIEIMLLKT 9
           TIEIMLL+T
Sbjct: 211 TIEIMLLET 219



>NP_060469
          Length = 1072

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TIEIMLLKT 9
           T+E++LL+T
Sbjct: 150 TLEVLLLRT 158



>NP_005684
          Length = 447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 295 IEVMLLET 302



>NP_001238863
          Length = 453

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 301 IEVMLLET 308



>NP_001238864
          Length = 453

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 301 IEVMLLET 308



>NP_001123574
          Length = 402

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 250 IEVMLLET 257



>XP_006718179
          Length = 402

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 250 IEVMLLET 257



>XP_005252773
          Length = 313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 161 IEVMLLET 168



>XP_005252772
          Length = 358

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 206 IEVMLLET 213



>XP_005252767
          Length = 402

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 250 IEVMLLET 257



>XP_005252766
          Length = 402

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 250 IEVMLLET 257



>XP_006718178
          Length = 402

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 250 IEVMLLET 257



>XP_006718177
          Length = 447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 295 IEVMLLET 302



>XP_005252764
          Length = 447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 295 IEVMLLET 302



>XP_005252763
          Length = 447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 295 IEVMLLET 302



>XP_006718176
          Length = 447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 295 IEVMLLET 302



>XP_006718175
          Length = 447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 295 IEVMLLET 302



>XP_005252762
          Length = 447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           IE+MLL+T
Sbjct: 295 IEVMLLET 302



>NP_573439
          Length = 1436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEIMLLKT 9
            I+IML+KT
Sbjct: 1002 IKIMLVKT 1009



>NP_573438
          Length = 1440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEIMLLKT 9
            I+IML+KT
Sbjct: 1008 IKIMLVKT 1015



>NP_001181930
          Length = 1433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEIMLLKT 9
            I+IML+KT
Sbjct: 999  IKIMLVKT 1006



>NP_005695
          Length = 1446

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEIMLLKT 9
            I+IML+KT
Sbjct: 1012 IKIMLVKT 1019



>XP_006710336
          Length = 1177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           I+IML+KT
Sbjct: 743 IKIMLVKT 750



>XP_006710335
          Length = 1370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           I+IML+KT
Sbjct: 936 IKIMLVKT 943



>XP_006710334
          Length = 1292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IEIMLLKT 9
           I+IML+KT
Sbjct: 858 IKIMLVKT 865



>XP_006710333
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEIMLLKT 9
            I+IML+KT
Sbjct: 1005 IKIMLVKT 1012



>XP_006710332
          Length = 1442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IEIMLLKT 9
            I+IML+KT
Sbjct: 1008 IKIMLVKT 1015



>NP_056494
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TIEIMLLK 8
          T+E+ LLK
Sbjct: 29 TVELQLLK 36



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.141    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 285,567
Number of extensions: 425
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)