Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              19     665
NP_001161879                                                           18    1935
NP_055804                                                              18    1935
XP_006715455                                                           18    1935
XP_006715452                                                           18    1935
XP_006715451                                                           18    1935
XP_006715450                                                           18    1935
XP_005248745                                                           18    1935
XP_005248744                                                           18    1935
XP_005248743                                                           18    1935
XP_005248742                                                           18    1935
XP_006715449                                                           18    1935
XP_006715448                                                           18    1935
XP_006715447                                                           18    1935
XP_006715446                                                           18    1935
NP_001009811                                                           17    4312
NP_055799                                                              17    4312
XP_005257233                                                           17    4312
XP_005257231                                                           17    4312
NP_116218                                                              16    5631
XP_006719717                                                           16    5631
XP_005254027                                                           16    5631
XP_006710433                                                           16    5631
XP_006710432                                                           16    5631
XP_006710431                                                           16    5631
XP_006710430                                                           16    5631
XP_006710429                                                           16    5631
NP_005367                                                              16    7355
NP_004970                                                              16    7355
NP_699188                                                              16    7355
NP_689870                                                              16    7355
NP_005928                                                              16    7355
NP_068591                                                              16    7355
NP_060529                                                              16    7355
NP_001129509                                                           16    7355
XP_006725391                                                           16    7355
XP_006725390                                                           16    7355
XP_006725389                                                           16    7355
XP_006725388                                                           16    7355
XP_006725387                                                           16    7355
XP_005258676                                                           16    7355
XP_005257438                                                           16    7355
XP_005257437                                                           16    7355
XP_006721974                                                           16    7355
XP_006721973                                                           16    7355
XP_005257436                                                           16    7355
XP_005256545                                                           16    7355
NP_114096                                                              16    7355
NP_001276024                                                           15    9605
NP_150594                                                              15    9605
NP_001234936                                                           15    9605
NP_006449                                                              15    9605
NP_001234935                                                           15    9605
NP_006565                                                              15    9605
NP_005771                                                              15    9605
NP_001009921                                                           15    9605
NP_001193872                                                           15    9605
NP_001193873                                                           15    9605
XP_006720705                                                           15    9605
XP_005247310                                                           15    9605
XP_005247308                                                           15    9605
XP_006713276                                                           15    9605
XP_005265313                                                           15    9605
XP_005265307                                                           15    9605
NP_056118                                                              15    9605
NP_001094874                                                           15    9605
>NP_115803
          Length = 1156

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   TGSGASQAL 9
           TGSGAS+AL
Sbjct: 416 TGSGASRAL 424
>NP_001161879
          Length = 1012

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TGSGASQAL 9
           TGSG+SQ L
Sbjct: 626 TGSGSSQEL 634
>NP_055804
          Length = 1692

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1306 TGSGSSQEL 1314
>XP_006715455
          Length = 474

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  TGSGASQAL 9
          TGSG+SQ L
Sbjct: 88 TGSGSSQEL 96
>XP_006715452
          Length = 1474

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1088 TGSGSSQEL 1096
>XP_006715451
          Length = 1475

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1098 TGSGSSQEL 1106
>XP_006715450
          Length = 1498

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1112 TGSGSSQEL 1120
>XP_005248745
          Length = 1515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1129 TGSGSSQEL 1137
>XP_005248744
          Length = 1519

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1133 TGSGSSQEL 1141
>XP_005248743
          Length = 1525

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1139 TGSGSSQEL 1147
>XP_005248742
          Length = 1535

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1149 TGSGSSQEL 1157
>XP_006715449
          Length = 1539

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1153 TGSGSSQEL 1161
>XP_006715448
          Length = 1549

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1163 TGSGSSQEL 1171
>XP_006715447
          Length = 1574

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1188 TGSGSSQEL 1196
>XP_006715446
          Length = 1574

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    TGSGASQAL 9
            TGSG+SQ L
Sbjct: 1188 TGSGSSQEL 1196
>NP_001009811
          Length = 1044

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TGSGASQAL 9
          TG G SQA+
Sbjct: 62 TGPGGSQAI 70
>NP_055799
          Length = 1080

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TGSGASQAL 9
          TG G SQA+
Sbjct: 62 TGPGGSQAI 70
>XP_005257233
          Length = 1046

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TGSGASQAL 9
          TG G SQA+
Sbjct: 62 TGPGGSQAI 70
>XP_005257231
          Length = 1080

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  TGSGASQAL 9
          TG G SQA+
Sbjct: 62 TGPGGSQAI 70
>NP_116218
          Length = 452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GSGASQAL 9
           G GA+QAL
Sbjct: 260 GQGATQAL 267
>XP_006719717
          Length = 452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GSGASQAL 9
           G GA+QAL
Sbjct: 260 GQGATQAL 267
>XP_005254027
          Length = 452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GSGASQAL 9
           G GA+QAL
Sbjct: 260 GQGATQAL 267
>XP_006710433
          Length = 1169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TGSGASQ 7
           TGSGAS+
Sbjct: 277 TGSGASR 283
>XP_006710432
          Length = 1202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TGSGASQ 7
           TGSGAS+
Sbjct: 277 TGSGASR 283
>XP_006710431
          Length = 1205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TGSGASQ 7
           TGSGAS+
Sbjct: 277 TGSGASR 283
>XP_006710430
          Length = 1226

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TGSGASQ 7
           TGSGAS+
Sbjct: 277 TGSGASR 283
>XP_006710429
          Length = 1238

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TGSGASQ 7
           TGSGAS+
Sbjct: 277 TGSGASR 283
>NP_005367
          Length = 236

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGSGASQAL 9
           +G G+SQAL
Sbjct: 220 SGIGSSQAL 228
>NP_004970
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGSGASQAL 9
           +GSG  QAL
Sbjct: 458 SGSGEEQAL 466
>NP_699188
          Length = 471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGSGASQAL 9
           TG+GAS  L
Sbjct: 171 TGNGASSLL 179
>NP_689870
          Length = 652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GSGASQ 7
           GSGASQ
Sbjct: 566 GSGASQ 571
>NP_005928
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 433 TGSGAS 438
>NP_068591
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GSGASQAL 9
           G GASQ L
Sbjct: 166 GDGASQGL 173
>NP_060529
          Length = 1075

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GSGASQ 7
           GSGASQ
Sbjct: 823 GSGASQ 828
>NP_001129509
          Length = 363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TGSGASQA 8
          TGSGA+ A
Sbjct: 13 TGSGAAPA 20
>XP_006725391
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 460 TGSGAS 465
>XP_006725390
          Length = 1004

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 344 TGSGAS 349
>XP_006725389
          Length = 1067

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 407 TGSGAS 412
>XP_006725388
          Length = 1094

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 434 TGSGAS 439
>XP_006725387
          Length = 1120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 460 TGSGAS 465
>XP_005258676
          Length = 652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GSGASQ 7
           GSGASQ
Sbjct: 566 GSGASQ 571
>XP_005257438
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 460 TGSGAS 465
>XP_005257437
          Length = 1004

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 344 TGSGAS 349
>XP_006721974
          Length = 1067

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 407 TGSGAS 412
>XP_006721973
          Length = 1094

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 434 TGSGAS 439
>XP_005257436
          Length = 1120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 460 TGSGAS 465
>XP_005256545
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGSGASQAL 9
           TG+GAS  L
Sbjct: 147 TGNGASSLL 155
>NP_114096
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   TGSGAS 6
           TGSGAS
Sbjct: 162 TGSGAS 167
>NP_001276024
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGSGASQAL 9
           +GSGAS  L
Sbjct: 471 SGSGASSPL 479
>NP_150594
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGSGASQAL 9
           TG G  QAL
Sbjct: 328 TGEGLRQAL 336
>NP_001234936
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGSGASQAL 9
           TG G  QAL
Sbjct: 209 TGEGLRQAL 217
>NP_006449
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGSGASQAL 9
           TG G  QAL
Sbjct: 328 TGEGLRQAL 336
>NP_001234935
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGSGASQAL 9
           TG G  QAL
Sbjct: 328 TGEGLRQAL 336
>NP_006565
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GSGASQAL 9
           GSG +QAL
Sbjct: 116 GSGDAQAL 123
>NP_005771
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TGSGASQAL 9
           TG+GA+ A+
Sbjct: 173 TGAGATAAM 181
>NP_001009921
          Length = 1428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGSGASQAL 9
           TG   SQAL
Sbjct: 457 TGGNVSQAL 465
>NP_001193872
          Length = 566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GSGASQAL 9
           GSG +QAL
Sbjct: 116 GSGDAQAL 123
>NP_001193873
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GSGASQAL 9
           GSG +QAL
Sbjct: 116 GSGDAQAL 123
>XP_006720705
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GSGASQAL 9
          G+G SQAL
Sbjct: 16 GAGDSQAL 23
>XP_005247310
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGSGASQAL 9
           TG   SQAL
Sbjct: 457 TGGNVSQAL 465
>XP_005247308
          Length = 1428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGSGASQAL 9
           TG   SQAL
Sbjct: 457 TGGNVSQAL 465
>XP_006713276
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGSGASQAL 9
           +GSGAS  L
Sbjct: 488 SGSGASSPL 496
>XP_005265313
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGSGASQAL 9
           +GSGAS  L
Sbjct: 488 SGSGASSPL 496
>XP_005265307
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   TGSGASQAL 9
           +GSGAS  L
Sbjct: 488 SGSGASSPL 496
>NP_056118
          Length = 1426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   TGSGASQAL 9
           TG   SQAL
Sbjct: 455 TGGNVSQAL 463
>NP_001094874
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GSGASQAL 9
          G+G SQAL
Sbjct: 16 GAGDSQAL 23
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.109    0.270 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 556,841
Number of extensions: 598
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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