Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_001004470                                                           18    1935
NP_689599                                                              17    2528
NP_001276876                                                           17    2528
NP_001276959                                                           17    2528
XP_005246354                                                           17    2528
NP_055672                                                              16    5631
NP_075044                                                              16    5631
NP_078989                                                              16    5631
XP_006711756                                                           16    5631
XP_005245738                                                           16    5631
XP_006711755                                                           16    5631
XP_005245737                                                           16    5631
NP_060797                                                              16    5631
NP_116281                                                              16    7355
NP_001273419                                                           16    7355
NP_001273420                                                           16    7355
XP_005254787                                                           16    7355
XP_005254786                                                           16    7355
NP_055627                                                              15    9605
NP_001035864                                                           15    9605
NP_001035863                                                           15    9605
NP_079225                                                              15    9605
NP_067058                                                              15    9605
NP_001245304                                                           15    9605
NP_001245303                                                           15    9605
NP_005133                                                              15    9605
NP_001245305                                                           15    9605
XP_006725047                                                           15    9605
XP_006725046                                                           15    9605
XP_006725045                                                           15    9605
XP_006725044                                                           15    9605
XP_006725043                                                           15    9605
XP_006725042                                                           15    9605
XP_006725041                                                           15    9605
XP_006725040                                                           15    9605
XP_006725039                                                           15    9605
XP_006725038                                                           15    9605
XP_006725037                                                           15    9605
XP_006722890                                                           15    9605
XP_006722889                                                           15    9605
XP_006722888                                                           15    9605
XP_006722887                                                           15    9605
XP_006722886                                                           15    9605
XP_005273967                                                           15    9605
XP_006714375                                                           15    9605
XP_005265836                                                           15    9605
XP_005265835                                                           15    9605
XP_006711915                                                           15    9605
XP_006711914                                                           15    9605
XP_006711913                                                           15    9605
XP_006711912                                                           15    9605
XP_006711911                                                           15    9605
XP_005273418                                                           15    9605
XP_006711910                                                           15    9605
XP_006711909                                                           15    9605
XP_006711908                                                           15    9605
XP_006711907                                                           15    9605
XP_006711906                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGQVSKDVM 9
            TG VSKDVM
Sbjct: 1927 TGLVSKDVM 1935
>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TGQVSKDVM 9
            TG VSKDVM
Sbjct: 1722 TGLVSKDVM 1730
>NP_001004470
          Length = 398

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   TGQVSKDV 8
           TG VSKDV
Sbjct: 219 TGDVSKDV 226
>NP_689599
          Length = 399

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   GQVSKDVM 9
           GQV+KDV+
Sbjct: 132 GQVAKDVL 139
>NP_001276876
          Length = 156

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TGQVSKDVM 9
          TG+VSKD +
Sbjct: 9  TGEVSKDAV 17
>NP_001276959
          Length = 436

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGQVSKDVM 9
           TG+VSKD +
Sbjct: 289 TGEVSKDAV 297
>XP_005246354
          Length = 271

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  GQVSKDVM 9
          GQV+KDV+
Sbjct: 4  GQVAKDVL 11
>NP_055672
          Length = 815

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TGQVSKD 7
           TG VSKD
Sbjct: 498 TGDVSKD 504
>NP_075044
          Length = 835

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GQVSKDV 8
           GQV KDV
Sbjct: 793 GQVGKDV 799
>NP_078989
          Length = 304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TGQVSKDV 8
           TG ++KDV
Sbjct: 289 TGNIAKDV 296
>XP_006711756
          Length = 985

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TGQVSKD 7
           TG VSKD
Sbjct: 498 TGDVSKD 504
>XP_005245738
          Length = 1014

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TGQVSKD 7
           TG VSKD
Sbjct: 461 TGDVSKD 467
>XP_006711755
          Length = 1051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TGQVSKD 7
           TG VSKD
Sbjct: 498 TGDVSKD 504
>XP_005245737
          Length = 1051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   TGQVSKD 7
           TG VSKD
Sbjct: 498 TGDVSKD 504
>NP_060797
          Length = 552

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TGQVSKDVM 9
           TG+V KDV+
Sbjct: 155 TGRVIKDVI 163
>NP_116281
          Length = 570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TGQVSKDVM 9
           +G+V+K+VM
Sbjct: 320 SGRVAKEVM 328
>NP_001273419
          Length = 414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TGQVSKDVM 9
           +G+V+K+VM
Sbjct: 226 SGRVAKEVM 234
>NP_001273420
          Length = 336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  TGQVSKDVM 9
          +G+V+K+VM
Sbjct: 86 SGRVAKEVM 94
>XP_005254787
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TGQVSKDVM 9
           +G+V+K+VM
Sbjct: 320 SGRVAKEVM 328
>XP_005254786
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   TGQVSKDVM 9
           +G+V+K+VM
Sbjct: 315 SGRVAKEVM 323
>NP_055627
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 969 TGSPSKDV 976
>NP_001035864
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 871 TGSPSKDV 878
>NP_001035863
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 871 TGSPSKDV 878
>NP_079225
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QVSKDV 8
            QVSKDV
Sbjct: 1148 QVSKDV 1153
>NP_067058
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGQVSKD 7
           TG++SKD
Sbjct: 325 TGKLSKD 331
>NP_001245304
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGQVSKD 7
           TG++SKD
Sbjct: 325 TGKLSKD 331
>NP_001245303
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGQVSKD 7
           TG++SKD
Sbjct: 325 TGKLSKD 331
>NP_005133
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQVSKDVM 9
           GQV KD++
Sbjct: 200 GQVLKDIV 207
>NP_001245305
          Length = 601

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGQVSKD 7
           TG++SKD
Sbjct: 325 TGKLSKD 331
>XP_006725047
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 871 TGSPSKDV 878
>XP_006725046
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 871 TGSPSKDV 878
>XP_006725045
          Length = 1496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 871 TGSPSKDV 878
>XP_006725044
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 969 TGSPSKDV 976
>XP_006725043
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_006725042
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 969 TGSPSKDV 976
>XP_006725041
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_006725040
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_006725039
          Length = 1629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_006725038
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_006725037
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_006722890
          Length = 750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGQVSKD 7
           TG++SKD
Sbjct: 325 TGKLSKD 331
>XP_006722889
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGQVSKD 7
           TG++SKD
Sbjct: 325 TGKLSKD 331
>XP_006722888
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGQVSKD 7
           TG++SKD
Sbjct: 325 TGKLSKD 331
>XP_006722887
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGQVSKD 7
           TG++SKD
Sbjct: 228 TGKLSKD 234
>XP_006722886
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TGQVSKD 7
           TG++SKD
Sbjct: 325 TGKLSKD 331
>XP_005273967
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQVSKDVM 9
           GQV KD++
Sbjct: 175 GQVLKDIV 182
>XP_006714375
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    QVSKDV 8
            QVSKDV
Sbjct: 1164 QVSKDV 1169
>XP_005265836
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGQVSKDVM 9
           TG + K+VM
Sbjct: 436 TGNMQKEVM 444
>XP_005265835
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   TGQVSKDVM 9
           TG + K+VM
Sbjct: 445 TGNMQKEVM 453
>XP_006711915
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 871 TGSPSKDV 878
>XP_006711914
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 871 TGSPSKDV 878
>XP_006711913
          Length = 1496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 871 TGSPSKDV 878
>XP_006711912
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 969 TGSPSKDV 976
>XP_006711911
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_005273418
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   TGQVSKDV 8
           TG  SKDV
Sbjct: 969 TGSPSKDV 976
>XP_006711910
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_006711909
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_006711908
          Length = 1629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_006711907
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
>XP_006711906
          Length = 1656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGQVSKDV 8
            TG  SKDV
Sbjct: 1031 TGSPSKDV 1038
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.121    0.305 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 542,341
Number of extensions: 919
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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