Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     665
XP_005262424                                                           19     665
NP_001124295                                                           17    3301
NP_001370                                                              17    3301
XP_006722744                                                           17    3301
NP_899236                                                              15    9605
NP_056363                                                              15    9605
NP_001138241                                                           15    9605
NP_001138242                                                           15    9605
NP_004037                                                              15    9605
NP_001785                                                              15    9605
NP_061092                                                              15    9605
NP_001032728                                                           15    9605
NP_001001937                                                           15    9605
NP_001398                                                              15    9605
NP_689865                                                              15    9605
NP_001201838                                                           15    9605
NP_001626                                                              15    9605
NP_001244263                                                           15    9605
NP_647477                                                              15    9605
XP_005254804                                                           15    9605
XP_006720791                                                           15    9605
XP_005254803                                                           15    9605
XP_005254800                                                           15    9605
XP_005254799                                                           15    9605
XP_006720281                                                           15    9605
XP_006720280                                                           15    9605
XP_006720279                                                           15    9605
XP_005267972                                                           15    9605
XP_005267971                                                           15    9605
XP_006720278                                                           15    9605
XP_005267970                                                           15    9605
XP_006715754                                                           15    9605
XP_006715753                                                           15    9605
XP_006715752                                                           15    9605
XP_006715232                                                           15    9605
XP_005249382                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
XP_005247642                                                           15    9605
XP_005247641                                                           15    9605
XP_005247640                                                           15    9605
XP_005247639                                                           15    9605
NP_001201835                                                           15    9605
NP_003913                                                              15    9605
NP_065766                                                              15    9605
>NP_722576
          Length = 3080

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TGLVSKNVM 9
            TGLVSK+VM
Sbjct: 1927 TGLVSKDVM 1935
>XP_005262424
          Length = 2875

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    TGLVSKNVM 9
            TGLVSK+VM
Sbjct: 1722 TGLVSKDVM 1730
>NP_001124295
          Length = 1632

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TGLVSKNV 8
           TGL+ KN+
Sbjct: 440 TGLIEKNI 447
>NP_001370
          Length = 1616

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TGLVSKNV 8
           TGL+ KN+
Sbjct: 424 TGLIEKNI 431
>XP_006722744
          Length = 1495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TGLVSKNV 8
           TGL+ KN+
Sbjct: 303 TGLIEKNI 310
>NP_899236
          Length = 5497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 2110 IISKNIM 2116
>NP_056363
          Length = 5171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 1784 IISKNIM 1790
>NP_001138241
          Length = 5675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 2288 IISKNIM 2294
>NP_001138242
          Length = 5537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 2150 IISKNIM 2156
>NP_004037
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GLVSKNVM 9
          GLVS+N +
Sbjct: 19 GLVSRNAL 26
>NP_001785
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  TGLVSKNVM 9
          T L+S+N++
Sbjct: 41 TALISQNIL 49
>NP_061092
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TGLVSKNVM 9
           TG+++ NV+
Sbjct: 170 TGIIAANVL 178
>NP_001032728
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TGLVSKNVM 9
           TG+++ NV+
Sbjct: 170 TGIIAANVL 178
>NP_001001937
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GLVSKNVM 9
          GLVS+N +
Sbjct: 19 GLVSRNAL 26
>NP_001398
          Length = 3312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    GLVSKNVM 9
            GLV+ N+M
Sbjct: 2318 GLVTPNIM 2325
>NP_689865
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TGLVSKNVM 9
          TGL S+NV+
Sbjct: 26 TGLGSENVI 34
>NP_001201838
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TGLVSKNVM 9
          TGL S+NV+
Sbjct: 26 TGLGSENVI 34
>NP_001626
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TGLVSKNV 8
          TG+ +KNV
Sbjct: 6  TGIFAKNV 13
>NP_001244263
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GLVSKNVM 9
          GLVS+N +
Sbjct: 19 GLVSRNAL 26
>NP_647477
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TGLVSKNV 8
          TG+ +KNV
Sbjct: 6  TGIFAKNV 13
>XP_005254804
          Length = 4796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGLVSKNV 8
            TGL  KNV
Sbjct: 4273 TGLQGKNV 4280
>XP_006720791
          Length = 4853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGLVSKNV 8
            TGL  KNV
Sbjct: 4330 TGLQGKNV 4337
>XP_005254803
          Length = 4854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGLVSKNV 8
            TGL  KNV
Sbjct: 4331 TGLQGKNV 4338
>XP_005254800
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGLVSKNV 8
            TGL  KNV
Sbjct: 4338 TGLQGKNV 4345
>XP_005254799
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGLVSKNV 8
            TGL  KNV
Sbjct: 4338 TGLQGKNV 4345
>XP_006720281
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TGLVSKNV 8
          +GLV KNV
Sbjct: 21 SGLVYKNV 28
>XP_006720280
          Length = 945

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TGLVSKNV 8
          +GLV KNV
Sbjct: 29 SGLVYKNV 36
>XP_006720279
          Length = 1191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLVSKNV 8
           +GLV KNV
Sbjct: 275 SGLVYKNV 282
>XP_005267972
          Length = 1325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLVSKNV 8
           +GLV KNV
Sbjct: 461 SGLVYKNV 468
>XP_005267971
          Length = 1344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLVSKNV 8
           +GLV KNV
Sbjct: 461 SGLVYKNV 468
>XP_006720278
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLVSKNV 8
           +GLV KNV
Sbjct: 461 SGLVYKNV 468
>XP_005267970
          Length = 1377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLVSKNV 8
           +GLV KNV
Sbjct: 461 SGLVYKNV 468
>XP_006715754
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TGLVSKNV 8
          TG+ +KNV
Sbjct: 6  TGIFAKNV 13
>XP_006715753
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TGLVSKNV 8
          TG+ +KNV
Sbjct: 6  TGIFAKNV 13
>XP_006715752
          Length = 1225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  TGLVSKNV 8
          TG+ +KNV
Sbjct: 6  TGIFAKNV 13
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4196 IISKNIM 4202
>XP_005249382
          Length = 5732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 2321 IISKNIM 2327
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 3870 IISKNIM 3876
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4196 IISKNIM 4202
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4222 IISKNIM 4228
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4229 IISKNIM 4235
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4236 IISKNIM 4242
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4269 IISKNIM 4275
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4407 IISKNIM 4413
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4312 IISKNIM 4318
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4374 IISKNIM 4380
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4407 IISKNIM 4413
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4407 IISKNIM 4413
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4386 IISKNIM 4392
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4407 IISKNIM 4413
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVSKNVM 9
            ++SKN+M
Sbjct: 4407 IISKNIM 4413
>XP_005247642
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TGLVSKNVM 9
           TG+++ NV+
Sbjct: 170 TGIIAANVL 178
>XP_005247641
          Length = 345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TGLVSKNVM 9
           TG+++ NV+
Sbjct: 170 TGIIAANVL 178
>XP_005247640
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TGLVSKNVM 9
           TG+++ NV+
Sbjct: 170 TGIIAANVL 178
>XP_005247639
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   TGLVSKNVM 9
           TG+++ NV+
Sbjct: 170 TGIIAANVL 178
>NP_001201835
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TGLVSKNVM 9
          TGL S+NV+
Sbjct: 26 TGLGSENVI 34
>NP_003913
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    TGLVSKNV 8
            TGL  KNV
Sbjct: 4338 TGLQGKNV 4345
>NP_065766
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TGLVSKNV 8
           +GLV KNV
Sbjct: 461 SGLVYKNV 468
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.125    0.316 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 391,900
Number of extensions: 550
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package