Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1935
XP_006718908                                                           18    1935
XP_005271621                                                           18    1935
XP_006718907                                                           18    1935
XP_006718906                                                           18    1935
XP_005271619                                                           18    1935
XP_005271618                                                           18    1935
NP_001264058                                                           17    3301
NP_001264055                                                           17    3301
NP_653288                                                              17    3301
NP_060941                                                              17    4312
NP_689856                                                              16    5631
NP_055426                                                              16    5631
NP_006659                                                              16    5631
NP_060387                                                              16    5631
XP_006720246                                                           16    5631
XP_006720245                                                           16    5631
XP_005267841                                                           16    5631
XP_006720244                                                           16    5631
XP_005267839                                                           16    5631
XP_005267331                                                           16    5631
XP_006715467                                                           16    5631
NP_150091                                                              16    7355
NP_001121689                                                           16    7355
NP_006637                                                              16    7355
NP_705618                                                              16    7355
NP_036588                                                              16    7355
NP_004289                                                              16    7355
NP_003418                                                              16    7355
NP_001265241                                                           16    7355
XP_005266296                                                           16    7355
XP_005249427                                                           16    7355
XP_005249426                                                           16    7355
XP_005249421                                                           16    7355
NP_001104026                                                           15    9605
NP_000171                                                              15    9605
NP_001447                                                              15    9605
NP_000923                                                              15    9605
NP_001276953                                                           15    9605
NP_001276952                                                           15    9605
NP_005526                                                              15    9605
NP_005098                                                              15    9605
NP_001138936                                                           15    9605
NP_001265435                                                           15    9605
NP_001020107                                                           15    9605
NP_001020106                                                           15    9605
NP_001020105                                                           15    9605
NP_001258547                                                           15    9605
NP_003922                                                              15    9605
NP_060077                                                              15    9605
XP_005259070                                                           15    9605
XP_006722804                                                           15    9605
XP_006720949                                                           15    9605
XP_005274109                                                           15    9605
XP_005267265                                                           15    9605
XP_006715658                                                           15    9605
XP_005267264                                                           15    9605
XP_005267263                                                           15    9605
XP_005267262                                                           15    9605
XP_005267261                                                           15    9605
XP_005267260                                                           15    9605
XP_005248250                                                           15    9605
XP_006713510                                                           15    9605
XP_006713509                                                           15    9605
XP_006713508                                                           15    9605
XP_006713507                                                           15    9605
XP_005265690                                                           15    9605
XP_006713506                                                           15    9605
XP_006713505                                                           15    9605
NP_001171812                                                           15    9605
NP_002475                                                              15    9605
NP_444270                                                              15    9605
>NP_000042
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TEISLQDLL 9
            T ISLQDLL
Sbjct: 1997 TGISLQDLL 2005
>XP_006718908
          Length = 1708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   TEISLQDLL 9
           T ISLQDLL
Sbjct: 649 TGISLQDLL 657
>XP_005271621
          Length = 2708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TEISLQDLL 9
            T ISLQDLL
Sbjct: 1649 TGISLQDLL 1657
>XP_006718907
          Length = 3050

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TEISLQDLL 9
            T ISLQDLL
Sbjct: 1991 TGISLQDLL 1999
>XP_006718906
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TEISLQDLL 9
            T ISLQDLL
Sbjct: 1997 TGISLQDLL 2005
>XP_005271619
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TEISLQDLL 9
            T ISLQDLL
Sbjct: 1997 TGISLQDLL 2005
>XP_005271618
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TEISLQDLL 9
            T ISLQDLL
Sbjct: 1997 TGISLQDLL 2005
>NP_001264058
          Length = 1004

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TEISLQDLL 9
           TE S+QDL+
Sbjct: 260 TECSMQDLI 268
>NP_001264055
          Length = 1062

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TEISLQDLL 9
           TE S+QDL+
Sbjct: 260 TECSMQDLI 268
>NP_653288
          Length = 1061

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TEISLQDLL 9
           TE S+QDL+
Sbjct: 260 TECSMQDLI 268
>NP_060941
          Length = 426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EISLQDLL 9
           EISL+DL+
Sbjct: 229 EISLEDLI 236
>NP_689856
          Length = 1749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ISLQDLL 9
           +SLQDLL
Sbjct: 444 VSLQDLL 450
>NP_055426
          Length = 5596

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EISLQDLL 9
           E+SL+DLL
Sbjct: 544 ELSLRDLL 551
>NP_006659
          Length = 500

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TEISLQDLL 9
           T +S+QD+L
Sbjct: 176 TPVSMQDML 184
>NP_060387
          Length = 453

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EISLQDLL 9
           +ISLQDL+
Sbjct: 405 KISLQDLI 412
>XP_006720246
          Length = 323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EISLQDLL 9
           +ISLQDL+
Sbjct: 275 KISLQDLI 282
>XP_006720245
          Length = 323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EISLQDLL 9
           +ISLQDL+
Sbjct: 275 KISLQDLI 282
>XP_005267841
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EISLQDLL 9
           +ISLQDL+
Sbjct: 295 KISLQDLI 302
>XP_006720244
          Length = 359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EISLQDLL 9
           +ISLQDL+
Sbjct: 311 KISLQDLI 318
>XP_005267839
          Length = 453

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EISLQDLL 9
           +ISLQDL+
Sbjct: 405 KISLQDLI 412
>XP_005267331
          Length = 355

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  TEISLQDLL 9
          T +S+QD+L
Sbjct: 31 TPVSMQDML 39
>XP_006715467
          Length = 5550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EISLQDLL 9
           E+SL+DLL
Sbjct: 544 ELSLRDLL 551
>NP_150091
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TEISLQD 7
           TEISL+D
Sbjct: 519 TEISLKD 525
>NP_001121689
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   TEISLQD 7
           TEISL+D
Sbjct: 519 TEISLKD 525
>NP_006637
          Length = 502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 EVSLQDI 95
>NP_705618
          Length = 1391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TEISLQDLL 9
            TEISLQ  L
Sbjct: 1107 TEISLQQRL 1115
>NP_036588
          Length = 90

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  TEISLQD 7
          TE+S+QD
Sbjct: 70 TELSMQD 76
>NP_004289
          Length = 1332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TEISLQDLL 9
            TEISLQ  L
Sbjct: 1048 TEISLQQRL 1056
>NP_003418
          Length = 570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEISLQDL 8
           TE+ L+DL
Sbjct: 115 TEVGLEDL 122
>NP_001265241
          Length = 1327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    TEISLQDLL 9
            TEISLQ  L
Sbjct: 1043 TEISLQQRL 1051
>XP_005266296
          Length = 499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 EVSLQDI 95
>XP_005249427
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEISLQDL 8
           TE+ L+DL
Sbjct: 115 TEVGLEDL 122
>XP_005249426
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEISLQDL 8
           TE+ L+DL
Sbjct: 115 TEVGLEDL 122
>XP_005249421
          Length = 570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   TEISLQDL 8
           TE+ L+DL
Sbjct: 115 TEVGLEDL 122
>NP_001104026
          Length = 2647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    EISLQDL 8
            EIS+QD+
Sbjct: 2168 EISIQDM 2174
>NP_000171
          Length = 1103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   TEISLQDLL 9
           T  SLQDLL
Sbjct: 623 TRGSLQDLL 631
>NP_001447
          Length = 2639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    EISLQDL 8
            EIS+QD+
Sbjct: 2160 EISIQDM 2166
>NP_000923
          Length = 1234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TEISLQDLL 9
           TE+ L+D+L
Sbjct: 385 TEVPLRDVL 393
>NP_001276953
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TEISLQD 7
           TE+SL+D
Sbjct: 688 TELSLED 694
>NP_001276952
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TEISLQD 7
           TE+SL+D
Sbjct: 648 TELSLED 654
>NP_005526
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TEISLQD 7
           TE+SL+D
Sbjct: 648 TELSLED 654
>NP_005098
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           ++SLQDL
Sbjct: 266 QVSLQDL 272
>NP_001138936
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           ++SLQDL
Sbjct: 216 QVSLQDL 222
>NP_001265435
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           E+SLQD+
Sbjct: 192 EVSLQDV 198
>NP_001020107
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>NP_001020106
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>NP_001020105
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>NP_001258547
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           +ISLQDL
Sbjct: 353 KISLQDL 359
>NP_003922
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>NP_060077
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           +ISLQDL
Sbjct: 353 KISLQDL 359
>XP_005259070
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           +ISLQDL
Sbjct: 353 KISLQDL 359
>XP_006722804
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   TEISLQD 7
           TE+SL+D
Sbjct: 648 TELSLED 654
>XP_006720949
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           E+SLQD+
Sbjct: 203 EVSLQDV 209
>XP_005274109
          Length = 1234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TEISLQDLL 9
           TE+ L+D+L
Sbjct: 385 TEVPLRDVL 393
>XP_005267265
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>XP_006715658
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>XP_005267264
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>XP_005267263
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>XP_005267262
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>XP_005267261
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>XP_005267260
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          E+SLQD+
Sbjct: 89 ELSLQDI 95
>XP_005248250
          Length = 1074

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          +ISLQDL
Sbjct: 68 KISLQDL 74
>XP_006713510
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           ++SLQDL
Sbjct: 126 QVSLQDL 132
>XP_006713509
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           ++SLQDL
Sbjct: 126 QVSLQDL 132
>XP_006713508
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           ++SLQDL
Sbjct: 126 QVSLQDL 132
>XP_006713507
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           ++SLQDL
Sbjct: 126 QVSLQDL 132
>XP_005265690
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           ++SLQDL
Sbjct: 126 QVSLQDL 132
>XP_006713506
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           ++SLQDL
Sbjct: 126 QVSLQDL 132
>XP_006713505
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           ++SLQDL
Sbjct: 163 QVSLQDL 169
>NP_001171812
          Length = 1167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TEISLQDLL 9
           TE+ L+D+L
Sbjct: 318 TEVPLRDVL 326
>NP_002475
          Length = 320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EISLQDL 8
           E+SLQD+
Sbjct: 203 EVSLQDV 209
>NP_444270
          Length = 1074

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  EISLQDL 8
          +ISLQDL
Sbjct: 68 KISLQDL 74
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.135    0.318 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 467,851
Number of extensions: 805
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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