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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_689810                                                              18    1482
XP_006720481                                                           18    1482
XP_006720480                                                           18    1482
XP_005254266                                                           18    1482
XP_006720479                                                           18    1482
XP_005254265                                                           18    1482
NP_001157717                                                           18    1935
NP_001157718                                                           18    1935
NP_060317                                                              18    1935
XP_006711463                                                           18    1935
XP_006711462                                                           18    1935
NP_003109                                                              16    5631
NP_443075                                                              16    5631
NP_056143                                                              16    5631
NP_001124194                                                           16    5631
NP_001124192                                                           16    5631
NP_001124195                                                           16    5631
XP_005250294                                                           16    5631
XP_006711892                                                           16    5631
XP_006711890                                                           16    5631
XP_005273367                                                           16    5631
XP_005273366                                                           16    5631
NP_061838                                                              16    7355
NP_001258750                                                           16    7355
NP_001273137                                                           16    7355
NP_001273134                                                           16    7355
NP_001472                                                              16    7355
NP_001273138                                                           16    7355
XP_005256366                                                           16    7355
XP_006721238                                                           16    7355
XP_005256361                                                           16    7355
NP_000180                                                              15    9605
NP_000179                                                              15    9605
NP_277033                                                              15    9605
NP_277032                                                              15    9605
NP_277035                                                              15    9605
NP_277031                                                              15    9605
NP_002106                                                              15    9605
NP_612152                                                              15    9605
NP_079406                                                              15    9605
XP_005269794                                                           15    9605
XP_005269793                                                           15    9605
XP_005269792                                                           15    9605
XP_006715715                                                           15    9605
XP_005264337                                                           15    9605

>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TAVVEETIG 9
            TA VEETIG
Sbjct: 1742 TAAVEETIG 1750



>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TAVVEETIG 9
            TA VEETIG
Sbjct: 1742 TAAVEETIG 1750



>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TAVVEETIG 9
            TA VEETIG
Sbjct: 1695 TAAVEETIG 1703



>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TAVVEETIG 9
            TA VEETIG
Sbjct: 1774 TAAVEETIG 1782



>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    TAVVEETIG 9
            TA VEETIG
Sbjct: 1774 TAAVEETIG 1782



>NP_689810
          Length = 581

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV EET+G
Sbjct: 179 TAVSEETVG 187



>XP_006720481
          Length = 406

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV EET+G
Sbjct: 179 TAVSEETVG 187



>XP_006720480
          Length = 581

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV EET+G
Sbjct: 179 TAVSEETVG 187



>XP_005254266
          Length = 581

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV EET+G
Sbjct: 179 TAVSEETVG 187



>XP_006720479
          Length = 581

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV EET+G
Sbjct: 179 TAVSEETVG 187



>XP_005254265
          Length = 581

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV EET+G
Sbjct: 179 TAVSEETVG 187



>NP_001157717
          Length = 431

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TAVVEETIG 9
          T +VEET+G
Sbjct: 4  TYIVEETVG 12



>NP_001157718
          Length = 422

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TAVVEETIG 9
          T +VEET+G
Sbjct: 4  TYIVEETVG 12



>NP_060317
          Length = 454

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TAVVEETIG 9
          T +VEET+G
Sbjct: 4  TYIVEETVG 12



>XP_006711463
          Length = 374

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TAVVEETIG 9
          T +VEET+G
Sbjct: 4  TYIVEETVG 12



>XP_006711462
          Length = 406

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  TAVVEETIG 9
          T +VEET+G
Sbjct: 4  TYIVEETVG 12



>NP_003109
          Length = 303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  TAVVEETI 8
          T VVEET+
Sbjct: 28 TEVVEETV 35



>NP_443075
          Length = 6620

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TAVVEETI 8
            T ++EETI
Sbjct: 6232 TVIIEETI 6239



>NP_056143
          Length = 611

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ ET+G
Sbjct: 239 TAVLMETLG 247



>NP_001124194
          Length = 508

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ ET+G
Sbjct: 136 TAVLMETLG 144



>NP_001124192
          Length = 610

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ ET+G
Sbjct: 238 TAVLMETLG 246



>NP_001124195
          Length = 508

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ ET+G
Sbjct: 136 TAVLMETLG 144



>XP_005250294
          Length = 509

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ ET+G
Sbjct: 137 TAVLMETLG 145



>XP_006711892
          Length = 6865

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TAVVEETI 8
            T ++EETI
Sbjct: 6477 TVIIEETI 6484



>XP_006711890
          Length = 6957

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TAVVEETI 8
            T ++EETI
Sbjct: 6569 TVIIEETI 6576



>XP_005273367
          Length = 7677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TAVVEETI 8
            T ++EETI
Sbjct: 7289 TVIIEETI 7296



>XP_005273366
          Length = 7678

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    TAVVEETI 8
            T ++EETI
Sbjct: 7290 TVIIEETI 7297



>NP_061838
          Length = 230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  TAVVEETIG 9
          TA+ ++T+G
Sbjct: 82 TAITDDTLG 90



>NP_001258750
          Length = 219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  TAVVEETIG 9
          TA+ ++T+G
Sbjct: 82 TAITDDTLG 90



>NP_001273137
          Length = 286

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ +T+G
Sbjct: 267 TAVIGQTLG 275



>NP_001273134
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ +T+G
Sbjct: 376 TAVIGQTLG 384



>NP_001472
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ +T+G
Sbjct: 459 TAVIGQTLG 467



>NP_001273138
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ +T+G
Sbjct: 434 TAVIGQTLG 442



>XP_005256366
          Length = 286

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ +T+G
Sbjct: 267 TAVIGQTLG 275



>XP_006721238
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ +T+G
Sbjct: 376 TAVIGQTLG 384



>XP_005256361
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   TAVVEETIG 9
           TAV+ +T+G
Sbjct: 434 TAVIGQTLG 442



>NP_000180
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 205 AVVNDTVG 212




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 653 AVVNDTVG 660



>NP_000179
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 205 AVVNDTVG 212




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 653 AVVNDTVG 660



>NP_277033
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 209 AVVNDTVG 216




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 657 AVVNDTVG 664



>NP_277032
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 209 AVVNDTVG 216




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 657 AVVNDTVG 664



>NP_277035
          Length = 905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 193 AVVNDTVG 200




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 641 AVVNDTVG 648



>NP_277031
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 204 AVVNDTVG 211




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 652 AVVNDTVG 659



>NP_002106
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 218 AVVNDTVG 225



>NP_612152
          Length = 2849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TAVVEETI 8
           TAV +ETI
Sbjct: 527 TAVTKETI 534



>NP_079406
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 652 AVVNDTVG 659



>XP_005269794
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 177 AVVNDTVG 184




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 625 AVVNDTVG 632



>XP_005269793
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 209 AVVNDTVG 216




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 657 AVVNDTVG 664



>XP_005269792
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 248 AVVNDTVG 255




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 696 AVVNDTVG 703



>XP_006715715
          Length = 2023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   TAVVEETI 8
           TAV +ETI
Sbjct: 479 TAVTKETI 486



>XP_005264337
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 205 AVVNDTVG 212




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AVVEETIG 9
           AVV +T+G
Sbjct: 674 AVVNDTVG 681



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.123    0.299 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 384,662
Number of extensions: 364
Number of successful extensions: 60
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)