Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              18    1135
NP_001263689                                                           18    1135
NP_001119584                                                           18    1135
NP_001119586                                                           18    1135
NP_001263625                                                           18    1135
NP_001119590                                                           18    1135
NP_001263690                                                           18    1135
NP_001119585                                                           18    1135
NP_001263624                                                           18    1135
NP_001119588                                                           18    1135
NP_001119587                                                           18    1135
NP_001119589                                                           18    1135
NP_001263627                                                           18    1135
NP_001263628                                                           18    1135
NP_001263626                                                           18    1135
NP_009089                                                              17    2528
NP_001007554                                                           17    2528
NP_001229820                                                           17    2528
NP_001123995                                                           17    2528
NP_001229822                                                           17    2528
NP_001229821                                                           17    2528
NP_778253                                                              17    3301
NP_001069                                                              16    5631
NP_001186763                                                           16    5631
NP_542413                                                              16    5631
NP_001123996                                                           16    5631
NP_859078                                                              16    5631
NP_001007227                                                           15    9605
NP_003554                                                              15    9605
NP_001007230                                                           15    9605
NP_001007228                                                           15    9605
NP_001007231                                                           15    9605
NP_001007229                                                           15    9605
NP_001238774                                                           15    9605
NP_001269404                                                           15    9605
NP_004873                                                              15    9605
NP_003908                                                              15    9605
NP_003295                                                              15    9605
XP_005257781                                                           15    9605
XP_005257780                                                           15    9605
XP_005268239                                                           15    9605
XP_005268238                                                           15    9605
XP_005268237                                                           15    9605
XP_005268236                                                           15    9605
XP_005268234                                                           15    9605
XP_005268235                                                           15    9605
XP_005268233                                                           15    9605
XP_005268231                                                           15    9605
XP_005268232                                                           15    9605
XP_005268230                                                           15    9605
XP_005268229                                                           15    9605
XP_005268228                                                           15    9605
XP_006720364                                                           15    9605
XP_005268227                                                           15    9605
XP_005268226                                                           15    9605
XP_005268225                                                           15    9605
XP_005268224                                                           15    9605
XP_005268223                                                           15    9605
XP_005247797                                                           15    9605
NP_113603                                                              15    9605
>NP_000537
          Length = 393

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 261 SGNLLGRNS 269
>NP_001263689
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 222 SGNLLGRNS 230
>NP_001119584
          Length = 393

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 261 SGNLLGRNS 269
>NP_001119586
          Length = 341

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 261 SGNLLGRNS 269
>NP_001263625
          Length = 302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 222 SGNLLGRNS 230
>NP_001119590
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 222 SGNLLGRNS 230
>NP_001263690
          Length = 354

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 222 SGNLLGRNS 230
>NP_001119585
          Length = 346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 261 SGNLLGRNS 269
>NP_001263624
          Length = 307

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 222 SGNLLGRNS 230
>NP_001119588
          Length = 209

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 129 SGNLLGRNS 137
>NP_001119587
          Length = 261

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 129 SGNLLGRNS 137
>NP_001119589
          Length = 214

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 129 SGNLLGRNS 137
>NP_001263627
          Length = 182

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 102 SGNLLGRNS 110
>NP_001263628
          Length = 187

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 102 SGNLLGRNS 110
>NP_001263626
          Length = 234

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           S NLLGRNS
Sbjct: 102 SGNLLGRNS 110
>NP_009089
          Length = 767

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VNLLGRNS 9
           V LLGRNS
Sbjct: 476 VRLLGRNS 483
>NP_001007554
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VNLLGRNS 9
           V LLGRNS
Sbjct: 507 VRLLGRNS 514
>NP_001229820
          Length = 844

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VNLLGRNS 9
           V LLGRNS
Sbjct: 553 VRLLGRNS 560
>NP_001123995
          Length = 813

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VNLLGRNS 9
           V LLGRNS
Sbjct: 522 VRLLGRNS 529
>NP_001229822
          Length = 767

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VNLLGRNS 9
           V LLGRNS
Sbjct: 476 VRLLGRNS 483
>NP_001229821
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VNLLGRNS 9
           V LLGRNS
Sbjct: 507 VRLLGRNS 514
>NP_778253
          Length = 578

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  SVNLLGRNS 9
          S+NL+GR++
Sbjct: 71 SINLMGRST 79
>NP_001069
          Length = 739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VNLLGRN 8
           VNL+G+N
Sbjct: 294 VNLIGKN 300
>NP_001186763
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VNLLGRN 8
           VNL+G+N
Sbjct: 232 VNLIGKN 238
>NP_542413
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VNLLGRN 8
           VNL+G+N
Sbjct: 294 VNLIGKN 300
>NP_001123996
          Length = 435

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           SVNLLG+
Sbjct: 178 SVNLLGK 184
>NP_859078
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VNLLGRNS 9
           +NLLGR S
Sbjct: 99  INLLGRPS 106
>NP_001007227
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           SVN+ G+N+
Sbjct: 167 SVNISGQNT 175
>NP_003554
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           SVN+ G+N+
Sbjct: 167 SVNISGQNT 175
>NP_001007230
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           SVN+ G+N+
Sbjct: 167 SVNISGQNT 175
>NP_001007228
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           SVN+ G+N+
Sbjct: 167 SVNISGQNT 175
>NP_001007231
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           SVN+ G+N+
Sbjct: 167 SVNISGQNT 175
>NP_001007229
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           SVN+ G+N+
Sbjct: 167 SVNISGQNT 175
>NP_001238774
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VNLLGRNS 9
          V++LGRN+
Sbjct: 80 VDVLGRNA 87
>NP_001269404
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 238 AVNILGR 244
>NP_004873
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NLLGRN 8
           N+LGRN
Sbjct: 184 NVLGRN 189
>NP_003908
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 310 AVNILGR 316
>NP_003295
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VNLLGRNS 9
          V++LGRN+
Sbjct: 80 VDVLGRNA 87
>XP_005257781
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           SVN+ G+N+
Sbjct: 167 SVNISGQNT 175
>XP_005257780
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SVNLLGRNS 9
           SVN+ G+N+
Sbjct: 167 SVNISGQNT 175
>XP_005268239
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 100 AVNILGR 106
>XP_005268238
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 401 AVNILGR 407
>XP_005268237
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 165 AVNILGR 171
>XP_005268236
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 181 AVNILGR 187
>XP_005268234
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 181 AVNILGR 187
>XP_005268235
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 181 AVNILGR 187
>XP_005268233
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 401 AVNILGR 407
>XP_005268231
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 238 AVNILGR 244
>XP_005268232
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 238 AVNILGR 244
>XP_005268230
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 310 AVNILGR 316
>XP_005268229
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 310 AVNILGR 316
>XP_005268228
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 344 AVNILGR 350
>XP_006720364
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 367 AVNILGR 373
>XP_005268227
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 367 AVNILGR 373
>XP_005268226
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 367 AVNILGR 373
>XP_005268225
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 367 AVNILGR 373
>XP_005268224
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 367 AVNILGR 373
>XP_005268223
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           +VN+LGR
Sbjct: 401 AVNILGR 407
>XP_005247797
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VNLLGRNS 9
          V++LGRN+
Sbjct: 80 VDVLGRNA 87
>NP_113603
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SVNLLGR 7
           SVN+LG+
Sbjct: 175 SVNILGK 181
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.127    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 536,768
Number of extensions: 1139
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package