Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001074025                                                           18    1482
XP_005256532                                                           18    1482
NP_659491                                                              18    1482
NP_001265612                                                           17    3301
XP_006721329                                                           17    4312
XP_006721328                                                           17    4312
NP_001265473                                                           16    5631
NP_000057                                                              16    5631
NP_001265472                                                           16    5631
NP_003217                                                              16    5631
XP_006719742                                                           16    5631
XP_005254043                                                           16    5631
XP_005264851                                                           16    5631
XP_005264850                                                           16    5631
XP_006712984                                                           16    5631
XP_005264847                                                           16    5631
XP_005271223                                                           16    5631
XP_006710936                                                           16    5631
NP_001990                                                              16    7355
NP_001243725                                                           16    7355
NP_852147                                                              16    7355
NP_852146                                                              16    7355
NP_001248327                                                           16    7355
NP_002551                                                              16    7355
NP_001003675                                                           16    7355
NP_001263178                                                           16    7355
NP_001003674                                                           16    7355
NP_001263180                                                           16    7355
NP_114120                                                              16    7355
XP_006722418                                                           16    7355
XP_006722417                                                           16    7355
XP_006722416                                                           16    7355
XP_006722415                                                           16    7355
XP_006722414                                                           16    7355
XP_006722413                                                           16    7355
XP_005258197                                                           16    7355
XP_006720336                                                           16    7355
XP_006720335                                                           16    7355
XP_005246213                                                           16    7355
XP_006711941                                                           16    7355
XP_006711940                                                           16    7355
XP_006711939                                                           16    7355
NP_036476                                                              16    7355
NP_001073291                                                           15    9605
NP_000417                                                              15    9605
NP_001074295                                                           15    9605
NP_004548                                                              15    9605
NP_079375                                                              15    9605
NP_060134                                                              15    9605
NP_775780                                                              15    9605
NP_031382                                                              15    9605
NP_009093                                                              15    9605
NP_001161299                                                           15    9605
NP_001258874                                                           15    9605
NP_001258873                                                           15    9605
NP_001258872                                                           15    9605
XP_006721641                                                           15    9605
XP_006721640                                                           15    9605
XP_005272427                                                           15    9605
XP_005272426                                                           15    9605
XP_005250289                                                           15    9605
XP_005267039                                                           15    9605
XP_005267038                                                           15    9605
XP_006715276                                                           15    9605
XP_006715275                                                           15    9605
XP_005249468                                                           15    9605
XP_005249469                                                           15    9605
XP_005244970                                                           15    9605
XP_006711240                                                           15    9605
XP_006711239                                                           15    9605
XP_006711238                                                           15    9605
XP_006711237                                                           15    9605
>NP_001074025
          Length = 552

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SVGVSASRC 9
           S+GVSA RC
Sbjct: 182 SLGVSAIRC 190
>XP_005256532
          Length = 531

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SVGVSASRC 9
           S+GVSA RC
Sbjct: 161 SLGVSAIRC 169
>NP_659491
          Length = 620

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SVGVSASRC 9
           S+GVSA RC
Sbjct: 250 SLGVSAIRC 258
>NP_001265612
          Length = 837

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SVGVSASRC 9
          SVG S +RC
Sbjct: 36 SVGCSGARC 44
>XP_006721329
          Length = 479

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           GVS SRC
Sbjct: 469 GVSLSRC 475
>XP_006721328
          Length = 479

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           GVS SRC
Sbjct: 469 GVSLSRC 475
>NP_001265473
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVGVSASRC 9
           S+GVS  +C
Sbjct: 333 SLGVSVGKC 341
>NP_000057
          Length = 591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVGVSASRC 9
           S+GVS  +C
Sbjct: 395 SLGVSVGKC 403
>NP_001265472
          Length = 539

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVGVSASRC 9
           S+GVS  +C
Sbjct: 343 SLGVSVGKC 351
>NP_003217
          Length = 94

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VGVSASRC 9
          VG+SA++C
Sbjct: 39 VGLSANQC 46
>XP_006719742
          Length = 336

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SVGVSASRC 9
          SVG++ S C
Sbjct: 40 SVGITGSSC 48
>XP_005254043
          Length = 371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SVGVSASRC 9
          SVG++ S C
Sbjct: 40 SVGITGSSC 48
>XP_005264851
          Length = 163

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVGVSAS 7
           SVGVSAS
Sbjct: 102 SVGVSAS 108
>XP_005264850
          Length = 171

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVGVSAS 7
           SVGVSAS
Sbjct: 110 SVGVSAS 116
>XP_006712984
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVGVSAS 7
           SVGVSAS
Sbjct: 260 SVGVSAS 266
>XP_005264847
          Length = 321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   SVGVSAS 7
           SVGVSAS
Sbjct: 260 SVGVSAS 266
>XP_005271223
          Length = 628

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVGVSASRC 9
           S+GVS  +C
Sbjct: 432 SLGVSVGKC 440
>XP_006710936
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SVGVSASRC 9
           S+GVS  +C
Sbjct: 434 SLGVSVGKC 442
>NP_001990
          Length = 2912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    VGVSASRC 9
            VGVS S C
Sbjct: 1599 VGVSRSSC 1606
>NP_001243725
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SVGVSASRC 9
           S GVS  RC
Sbjct: 157 SNGVSTGRC 165
>NP_852147
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 218 GISASTC 224
>NP_852146
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 236 GISASTC 242
>NP_001248327
          Length = 341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SVGVSASRC 9
           S GVS  RC
Sbjct: 141 SNGVSTGRC 149
>NP_002551
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SVGVSASRC 9
           S GVS  RC
Sbjct: 141 SNGVSTGRC 149
>NP_001003675
          Length = 251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 181 GISASTC 187
>NP_001263178
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 159 GISASTC 165
>NP_001003674
          Length = 269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 199 GISASTC 205
>NP_001263180
          Length = 208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 138 GISASTC 144
>NP_114120
          Length = 645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SVGVSASRC 9
           SVG   SRC
Sbjct: 552 SVGQEMSRC 560
>XP_006722418
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 236 GISASTC 242
>XP_006722417
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 236 GISASTC 242
>XP_006722416
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 236 GISASTC 242
>XP_006722415
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 236 GISASTC 242
>XP_006722414
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 236 GISASTC 242
>XP_006722413
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 236 GISASTC 242
>XP_005258197
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SAS C
Sbjct: 236 GISASTC 242
>XP_006720336
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SVGVSASRC 9
           SVG   SRC
Sbjct: 481 SVGQEMSRC 489
>XP_006720335
          Length = 645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SVGVSASRC 9
           SVG   SRC
Sbjct: 552 SVGQEMSRC 560
>XP_005246213
          Length = 250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SA RC
Sbjct: 128 GLSAERC 134
>XP_006711941
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SA RC
Sbjct: 128 GLSAERC 134
>XP_006711940
          Length = 319

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SA RC
Sbjct: 128 GLSAERC 134
>XP_006711939
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SA RC
Sbjct: 128 GLSAERC 134
>NP_036476
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           G+SA RC
Sbjct: 128 GLSAERC 134
>NP_001073291
          Length = 3118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   GVSASRC 9
           GVS  RC
Sbjct: 450 GVSCDRC 456
>NP_000417
          Length = 3122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   GVSASRC 9
           GVS  RC
Sbjct: 450 GVSCDRC 456
>NP_001074295
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           GV+ SRC
Sbjct: 384 GVTPSRC 390
>NP_004548
          Length = 2003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    VGVSASRC 9
            +GV  SRC
Sbjct: 1385 MGVDLSRC 1392
>NP_079375
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SVGVSASRC 9
            S+G+ AS C
Sbjct: 1209 SLGILASSC 1217
>NP_060134
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   SVGVSASRC 9
           SVG +  RC
Sbjct: 207 SVGTNRKRC 215
>NP_775780
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  GVSASRC 9
          GV+AS C
Sbjct: 89 GVAASHC 95
>NP_031382
          Length = 1761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3    GVSASRC 9
            GVS  RC
Sbjct: 1152 GVSGQRC 1158
>NP_009093
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VGVSASRC 9
           VGV++S C
Sbjct: 205 VGVTSSSC 212
>NP_001161299
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VGVSASRC 9
           VGV++S C
Sbjct: 219 VGVTSSSC 226
>NP_001258874
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VGVSASRC 9
           VGV++S C
Sbjct: 205 VGVTSSSC 212
>NP_001258873
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VGVSASRC 9
           VGV++S C
Sbjct: 205 VGVTSSSC 212
>NP_001258872
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VGVSASRC 9
           VGV++S C
Sbjct: 120 VGVTSSSC 127
>XP_006721641
          Length = 1140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SVGVSASRC 9
            S+G+ AS C
Sbjct: 1132 SLGILASSC 1140
>XP_006721640
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SVGVSASRC 9
            S+G+ AS C
Sbjct: 1166 SLGILASSC 1174
>XP_005272427
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           GV+ SRC
Sbjct: 384 GVTPSRC 390
>XP_005272426
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVSASRC 9
           GV+ SRC
Sbjct: 384 GVTPSRC 390
>XP_005250289
          Length = 1761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3    GVSASRC 9
            GVS  RC
Sbjct: 1152 GVSGQRC 1158
>XP_005267039
          Length = 3206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   GVSASRC 9
           GVS  RC
Sbjct: 450 GVSCDRC 456
>XP_005267038
          Length = 3210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   GVSASRC 9
           GVS  RC
Sbjct: 450 GVSCDRC 456
>XP_006715276
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VGVSASRC 9
           VGV++S C
Sbjct: 205 VGVTSSSC 212
>XP_006715275
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VGVSASRC 9
           VGV++S C
Sbjct: 205 VGVTSSSC 212
>XP_005249468
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VGVSASRC 9
           VGV++S C
Sbjct: 205 VGVTSSSC 212
>XP_005249469
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VGVSASRC 9
           VGV++S C
Sbjct: 205 VGVTSSSC 212
>XP_005244970
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  GVSASRC 9
          GV+AS C
Sbjct: 89 GVAASHC 95
>XP_006711240
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  GVSASRC 9
          GV+AS C
Sbjct: 89 GVAASHC 95
>XP_006711239
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  GVSASRC 9
          GV+AS C
Sbjct: 89 GVAASHC 95
>XP_006711238
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  GVSASRC 9
          GV+AS C
Sbjct: 89 GVAASHC 95
>XP_006711237
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  GVSASRC 9
          GV+AS C
Sbjct: 89 GVAASHC 95
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.119    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 427,081
Number of extensions: 854
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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