Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001276866                                                           18    1935
NP_004439                                                              18    1935
NP_001276865                                                           18    1935
NP_001005862                                                           18    1935
XP_005257197                                                           18    1935
XP_006721828                                                           18    1935
NP_005219                                                              17    2528
NP_001385                                                              16    7355
NP_057336                                                              15    9605
NP_001165375                                                           15    9605
NP_055518                                                              15    9605
XP_005276812                                                           15    9605
XP_006713491                                                           15    9605
XP_005276811                                                           15    9605
XP_006713490                                                           15    9605
XP_005276810                                                           15    9605
XP_005276809                                                           15    9605
XP_006713489                                                           15    9605
XP_005276808                                                           15    9605
XP_006712120                                                           15    9605
XP_005264512                                                           15    9605
XP_005264511                                                           15    9605
XP_006712119                                                           15    9605
XP_005264510                                                           15    9605
XP_006712118                                                           15    9605
XP_005264509                                                           15    9605
XP_005264508                                                           15    9605
XP_006712117                                                           15    9605
XP_005264507                                                           15    9605
XP_005264506                                                           15    9605
>NP_001276866
          Length = 1055

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           STVQLV QL
Sbjct: 792 STVQLVTQL 800
>NP_004439
          Length = 1255

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           STVQLV QL
Sbjct: 792 STVQLVTQL 800
>NP_001276865
          Length = 1240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           STVQLV QL
Sbjct: 777 STVQLVTQL 785
>NP_001005862
          Length = 1225

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           STVQLV QL
Sbjct: 762 STVQLVTQL 770
>XP_005257197
          Length = 1225

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           STVQLV QL
Sbjct: 762 STVQLVTQL 770
>XP_006721828
          Length = 1336

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           STVQLV QL
Sbjct: 873 STVQLVTQL 881
>NP_005219
          Length = 1210

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           STVQL+ QL
Sbjct: 784 STVQLITQL 792
>NP_001385
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   STVQLVIQ 8
           STV LV+Q
Sbjct: 122 STVSLVVQ 129
>NP_057336
          Length = 4857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2626 TSQLIIQL 2633
>NP_001165375
          Length = 1506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           S VQL++QL
Sbjct: 594 SCVQLLLQL 602
>NP_055518
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           S VQL++QL
Sbjct: 595 SCVQLLLQL 603
>XP_005276812
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           S VQL++QL
Sbjct: 595 SCVQLLLQL 603
>XP_006713491
          Length = 1425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           S VQL++QL
Sbjct: 513 SCVQLLLQL 521
>XP_005276811
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           S VQL++QL
Sbjct: 595 SCVQLLLQL 603
>XP_006713490
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           S VQL++QL
Sbjct: 595 SCVQLLLQL 603
>XP_005276810
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           S VQL++QL
Sbjct: 595 SCVQLLLQL 603
>XP_005276809
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           S VQL++QL
Sbjct: 595 SCVQLLLQL 603
>XP_006713489
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           S VQL++QL
Sbjct: 595 SCVQLLLQL 603
>XP_005276808
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   STVQLVIQL 9
           S VQL++QL
Sbjct: 595 SCVQLLLQL 603
>XP_006712120
          Length = 4812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2581 TSQLIIQL 2588
>XP_005264512
          Length = 4840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2609 TSQLIIQL 2616
>XP_005264511
          Length = 4847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2653 TSQLIIQL 2660
>XP_006712119
          Length = 4851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2620 TSQLIIQL 2627
>XP_005264510
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2630 TSQLIIQL 2637
>XP_006712118
          Length = 4864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2653 TSQLIIQL 2660
>XP_005264509
          Length = 4870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2639 TSQLIIQL 2646
>XP_005264508
          Length = 4875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2644 TSQLIIQL 2651
>XP_006712117
          Length = 4878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2647 TSQLIIQL 2654
>XP_005264507
          Length = 4880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2649 TSQLIIQL 2656
>XP_005264506
          Length = 4884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVQLVIQL 9
            T QL+IQL
Sbjct: 2653 TSQLIIQL 2660
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.135    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 243,463
Number of extensions: 325
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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