Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443157                                                              18    1935
XP_005258543                                                           18    1935
XP_006726249                                                           18    1935
XP_005258542                                                           18    1935
XP_005258541                                                           18    1935
XP_005258540                                                           18    1935
XP_006726248                                                           18    1935
XP_005258539                                                           18    1935
XP_005258538                                                           18    1935
XP_005277301                                                           18    1935
XP_006726369                                                           18    1935
XP_005277300                                                           18    1935
XP_005277299                                                           18    1935
XP_005277298                                                           18    1935
XP_006726368                                                           18    1935
XP_005277297                                                           18    1935
XP_005277296                                                           18    1935
XP_006726331                                                           18    1935
XP_005277122                                                           18    1935
XP_005277120                                                           18    1935
XP_006726330                                                           18    1935
XP_005277119                                                           18    1935
XP_005277118                                                           18    1935
XP_006723060                                                           18    1935
XP_005278309                                                           18    1935
XP_005278307                                                           18    1935
XP_006723059                                                           18    1935
XP_005278306                                                           18    1935
XP_005278305                                                           18    1935
NP_000236                                                              17    4312
NP_001120972                                                           17    4312
NP_006284                                                              17    4312
XP_006716052                                                           17    4312
XP_006716051                                                           17    4312
NP_008986                                                              16    5631
NP_001244                                                              16    5631
XP_006717660                                                           16    5631
XP_006715352                                                           16    5631
NP_003144                                                              15    9605
NP_001171549                                                           15    9605
NP_001171550                                                           15    9605
NP_001171551                                                           15    9605
NP_001171552                                                           15    9605
XP_006719638                                                           15    9605
XP_006719637                                                           15    9605
XP_006719636                                                           15    9605
>NP_443157
          Length = 800

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>XP_005258543
          Length = 800

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>XP_006726249
          Length = 819

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 222 SARGNLSGK 230
>XP_005258542
          Length = 837

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 240 SARGNLSGK 248
>XP_005258541
          Length = 837

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 240 SARGNLSGK 248
>XP_005258540
          Length = 856

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 259 SARGNLSGK 267
>XP_006726248
          Length = 856

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 259 SARGNLSGK 267
>XP_005258539
          Length = 874

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>XP_005258538
          Length = 874

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>XP_005277301
          Length = 800

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>XP_006726369
          Length = 819

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 222 SARGNLSGK 230
>XP_005277300
          Length = 837

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 240 SARGNLSGK 248
>XP_005277299
          Length = 837

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 240 SARGNLSGK 248
>XP_005277298
          Length = 856

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 259 SARGNLSGK 267
>XP_006726368
          Length = 856

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 259 SARGNLSGK 267
>XP_005277297
          Length = 874

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>XP_005277296
          Length = 874

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>XP_006726331
          Length = 819

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 222 SARGNLSGK 230
>XP_005277122
          Length = 837

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 240 SARGNLSGK 248
>XP_005277120
          Length = 856

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 259 SARGNLSGK 267
>XP_006726330
          Length = 856

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 259 SARGNLSGK 267
>XP_005277119
          Length = 874

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>XP_005277118
          Length = 874

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>XP_006723060
          Length = 819

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 222 SARGNLSGK 230
>XP_005278309
          Length = 837

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 240 SARGNLSGK 248
>XP_005278307
          Length = 856

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 259 SARGNLSGK 267
>XP_006723059
          Length = 856

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 259 SARGNLSGK 267
>XP_005278306
          Length = 874

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>XP_005278305
          Length = 874

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   STRANLSGK 9
           S R NLSGK
Sbjct: 277 SARGNLSGK 285
>NP_000236
          Length = 1390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   STRANLSG 8
           S++ANLSG
Sbjct: 102 SSKANLSG 109
>NP_001120972
          Length = 1408

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   STRANLSG 8
           S++ANLSG
Sbjct: 102 SSKANLSG 109
>NP_006284
          Length = 890

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TRANLSG 8
           TRANL+G
Sbjct: 377 TRANLTG 383
>XP_006716052
          Length = 1409

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   STRANLSG 8
           S++ANLSG
Sbjct: 121 SSKANLSG 128
>XP_006716051
          Length = 1427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   STRANLSG 8
           S++ANLSG
Sbjct: 121 SSKANLSG 128
>NP_008986
          Length = 1390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RANLSGK 9
           R NLSGK
Sbjct: 353 RGNLSGK 359
>NP_001244
          Length = 802

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TRANLSGK 9
           TRANL+ K
Sbjct: 678 TRANLASK 685
>XP_006717660
          Length = 1369

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RANLSGK 9
           R NLSGK
Sbjct: 332 RGNLSGK 338
>XP_006715352
          Length = 730

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TRANLSGK 9
           TRANL+ K
Sbjct: 678 TRANLASK 685
>NP_003144
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TRANLSGK 9
           TRA+L+G+
Sbjct: 253 TRASLTGR 260
>NP_001171549
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TRANLSGK 9
           TRA+L+G+
Sbjct: 253 TRASLTGR 260
>NP_001171550
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TRANLSGK 9
           TRA+L+G+
Sbjct: 253 TRASLTGR 260
>NP_001171551
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TRANLSGK 9
           TRA+L+G+
Sbjct: 143 TRASLTGR 150
>NP_001171552
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TRANLSGK 9
           TRA+L+G+
Sbjct: 143 TRASLTGR 150
>XP_006719638
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TRANLSGK 9
           TRA+L+G+
Sbjct: 253 TRASLTGR 260
>XP_006719637
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TRANLSGK 9
           TRA+L+G+
Sbjct: 253 TRASLTGR 260
>XP_006719636
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TRANLSGK 9
           TRA+L+G+
Sbjct: 253 TRASLTGR 260
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.110    0.270 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 428,254
Number of extensions: 742
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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